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Active, not recruiting Phase 2 Interventional Results available

Carboplatin and Nab-Paclitaxel With or Without Vorinostat in Treating Women With Newly Diagnosed Operable Breast Cancer

ClinicalTrials.gov ID: NCT00616967

Public ClinicalTrials.gov record NCT00616967. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 20, 2026, 5:21 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multi-Institutional Double-Blind Phase II Study Evaluating Response and Surrogate Biomarkers to Carboplatin and Nab-Paclitaxel (CP) With or Without Vorinostat as Preoperative Chemotherapy in HER2-negative Primary Operable Breast Cancer

Study identification

NCT ID
NCT00616967
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Enrollment
68 participants

Conditions and interventions

Conditions

Interventions

  • carboplatin Drug
  • paclitaxel albumin-stabilized nanoparticle formulation Drug
  • placebo Other
  • vorinostat Drug

Drug · Other

Eligibility (public fields only)

Age range
18 Years and older
Sex
Female
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 30, 2008
Primary completion
May 31, 2014
Completion
Jan 31, 2027
Last update posted
Mar 4, 2026

2008 – 2027

United States locations

U.S. sites
5
U.S. states
4
U.S. cities
5
Facility City State ZIP Site status
University of Alabama Comprehensive Cancer Center Birmingham Alabama 35249
Indiana University Purdue University of Indianapolis Indianapolis Indiana 46202
Anne Arundel Health System Annapolis Maryland 21401
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore Maryland 21231-2410
Mayo Clinic Cancer Center Rochester Minnesota 55905

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00616967, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 4, 2026 · Synced May 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00616967 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →