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Completed Phase 3 Interventional Results available

Efficacy and Safety of Concentration-controlled Everolimus to Eliminate or to Reduce Tacrolimus Compared to Tacrolimus in de Novo Liver Transplant Recipients

ClinicalTrials.gov ID: NCT00622869

Public ClinicalTrials.gov record NCT00622869. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 24, 2026, 3:37 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A 24 Month, Multicenter, Open-label, Randomized, Controlled Study to Evaluate the Efficacy and Safety of Concentration-controlled Everolimus to Eliminate or to Reduce Tacrolimus Compared to Tacrolimus in de Novo Liver Transplant Recipients

Study identification

NCT ID
NCT00622869
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
719 participants

Conditions and interventions

Interventions

  • Tacrolimus (reduced tacrolimus) Drug
  • Tacrolimus (tacrolimus elimination) Drug
  • Tacrolimus (tacrolimus control) Drug
  • Everolimus (reduced tacrolimus) Drug
  • Everolimus (tacrolimus elimination) Drug
  • Corticosteroids Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 70 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 31, 2007
Primary completion
Mar 31, 2012
Completion
Mar 31, 2012
Last update posted
May 26, 2013

2008 – 2012

United States locations

U.S. sites
28
U.S. states
20
U.S. cities
23
Facility City State ZIP Site status
Novartis Investigative Site Los Angeles California 90033
Novartis Investigative Site Los Angeles California 90048
Novartis Investigative Site Los Angeles California 90095
Novartis Investigative Site San Francisco California 94143
Novartis Investigative Site Aurora Colorado 80045
Novartis Investigative Site Washington D.C. District of Columbia 20007-2197
Novartis Investigative Site Tampa Florida 33606
Novartis Investigative Site Atlanta Georgia 30309
Novartis Investigative Site Chicago Illinois 60637
Novartis Investigative Site Lexington Kentucky 40536-0293
Novartis Investigative Site Detroit Michigan 48202-2689
Novartis Investigative Site Rochester Minnesota 55905
Novartis Investigative Site St Louis Missouri 63110
Novartis Investigative Site Newark New Jersey 07101
Novartis Investigative Site New York New York 10016
Novartis Investigative Site New York New York 10032
Novartis Investigative Site Chapel Hill North Carolina 27599
Novartis Investigative Site Durham North Carolina 27710
Novartis Investigative Site Cleveland Ohio 44195
Novartis Investigative Site Oklahoma City Oklahoma 73112
Novartis Investigative Site Portland Oregon 97201-3098
Novartis Investigative Site Philadelphia Pennsylvania 19107
Novartis Investigative Site Charleston South Carolina 29425
Novartis Investigative Site Nashville Tennessee 37232
Novartis Investigative Site Dallas Texas 75208-2312
Novartis Investigative Site Dallas Texas 75246
Novartis Investigative Site Houston Texas 77030-2400
Novartis Investigative Site Houston Texas 77030

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 63 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00622869, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 26, 2013 · Synced Jul 24, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00622869 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →