Transthyretin Amyloidosis Outcome Survey (THAOS)
Public ClinicalTrials.gov record NCT00628745. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Transthyretin Amyloidosis Outcomes Survey (THAOS): A Global, Multi-Center, Longitudinal, Observational Survey of Patients With Documented Transthyretin Gene Mutations or Wild-Type Transthyretin Amyloidosis.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
THAOS is a global, multi-center, longitudinal observational survey open to all patients with transthyretin amyloidosis (ATTR), including ATTR-PN (polyneuropathy), ATTR-CM (cardiomyopathy) and wild-type ATTR-CM. It is open-ended with a minimum duration of 10 years. Patients will be followed as long as they are able to participate. The principal aims of this outcome survey are to better understand and characterize the natural history of the disease by studying a large and heterogenous patient population. Survey data may be used to develop new treatment guidelines and recommendations, and to inform and educate clinicians about the management of this disease.
Study identification
- NCT ID
- NCT00628745
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 6,718 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 4, 2008 (Actual)
- Primary completion
- Jun 16, 2023 (Actual)
- Completion
- Jun 19, 2023 (Actual)
- Last update posted
- Nov 22, 2024
2008 – 2023
United States locations
- U.S. sites
- 47
- U.S. states
- 20
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Mayo Clinic Arizona | Phoenix | Arizona | 85054 | — |
| VA Greater Los Angeles Healthcare System | Los Angeles | California | 90073 | — |
| University of California, Irvine | Orange | California | 92868 | — |
| University of California - San Francisco, UCSF Department of Neurology | San Francisco | California | 94117 | — |
| Office of Sponsored Research | San Francisco | California | 94143 | — |
| Stanford University School of Medicine | Stanford | California | 94305-5406 | — |
| UC Denver | Aurora | Colorado | 80045 | — |
| Smilow Cancer Hospital at Yale-New Haven | New Haven | Connecticut | 06510 | — |
| UHealth Deerfield Beach | Deerfield Beach | Florida | 33442 | — |
| University of Miami Hospital & Clinics | Miami | Florida | 33136 | — |
| UHealth Plantation | Plantation | Florida | 33324 | — |
| Clinical Trials Unit | Chicago | Illinois | 60611 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| University of Chicago Medical Center IRB | Chicago | Illinois | 60637 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Advocate Christ Medical Centre | Oak Lawn | Illinois | 60453 | — |
| John Ochsner Heart & Vascular Institute | New Orleans | Louisiana | 70121 | — |
| University of Maryland School of Medicine | Baltimore | Maryland | 21201 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| Johns Hopkins Hospital | Baltimore | Maryland | 21287 | — |
| Harvard Vanguard Medical Associates | Boston | Massachusetts | 02215 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| NYU Medical Center | New York | New York | 10016 | — |
| Columbia University Medical Center | New York | New York | 10034 | — |
| Cardiology Clinic at Montefiore Hutchinson Campus | The Bronx | New York | 10461 | — |
| Montefiore Medical Center-Jack D. Weiler Hospital | The Bronx | New York | 10461 | — |
| Congestive Heart Failure Clinic | The Bronx | New York | 10467 | — |
| Montefiore Moses Division | The Bronx | New York | 10467 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| The Ohio University College of Medicine | Columbus | Ohio | 43210 | — |
| OSU Wexner Medical Center | Columbus | Ohio | 43221 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Peters Township Health and Wellness Pavillion | McMurray | Pennsylvania | 15317 | — |
| Penn Presbyterian Medical Center-University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| University of Pennsylvania - Perelman Center for Advanced Medicine | Philadelphia | Pennsylvania | 19104 | — |
| Temple University School of Medicine | Philadelphia | Pennsylvania | 19140 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| Admin | Pittsburgh | Pennsylvania | 15213 | — |
| University of Pittsburgh Medical Center (UPMC) | Pittsburgh | Pennsylvania | 15213 | — |
| Wexford Health and Wellness Pavillion | Wexford | Pennsylvania | 15090 | — |
| IRB | Nashville | Tennessee | 37232 | — |
| Vanderbilt University School of Medicine | Nashville | Tennessee | 37232 | — |
| The University of Utah Health Sciences Center | Salt Lake City | Utah | 84132 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 66 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00628745, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 22, 2024 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00628745 live on ClinicalTrials.gov.