Extension to Safety and Efficacy of Probuphine in the Treatment of Opioid Dependence
Public ClinicalTrials.gov record NCT00630201. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label, Multi-Center Extension Study Of Probuphine in Patients With Opioid Dependence
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Buprenorphine (BPN) is an approved treatment for opioid dependence; however, in taking oral tablets, patients experience withdrawal and cravings when the variable BPN levels in the blood are low. Probuphine (buprenorphine implant) is an implant placed just beneath the skin that contains BPN. It is designed to provide 6 months of stable BPN blood levels. This study will test the safety and efficacy of Probuphine in the treatment of patient with opioid dependence. Patients who have completed 24 weeks of treatment in the Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study of Probuphine in Patients with Opioid Dependence, will be re-treated with Probuphine over an additional 24 weeks.
Study identification
- NCT ID
- NCT00630201
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 62 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2007 (Type not available)
- Primary completion
- Feb 2009 (Actual)
- Completion
- Feb 2009 (Actual)
- Last update posted
- Dec 31, 2018
2007 – 2009
United States locations
- U.S. sites
- 15
- U.S. states
- 11
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| David Geffen School of Medicine at UCLA | Los Angeles | California | — | — |
| Synergy Clinical Research Center | National City | California | 91950 | — |
| Amit Vijapura, MD | Jacksonville | Florida | 32256 | — |
| Fidelity Clinical Research, Inc. | Lauderhill | Florida | — | — |
| Scientific Clinical Research, Inc. | North Miami | Florida | 33161 | — |
| Behavioral Biology Research Unit, Johns Hopkins Bayview Campus | Baltimore | Maryland | — | — |
| Dual Diagnosis Unit, SSTAR: Stanley Street Treatment and Resources, Inc. | Fall River | Massachusetts | — | — |
| Wayne State Univ. School of Medicine, Dept of Psychiatry & Behavioral Neuroscience | Detroit | Michigan | — | — |
| Psych Care Consultants Research | St Louis | Missouri | 63128 | — |
| New York VA Medical Center, NYU School of Medicine | New York | New York | — | — |
| Duke Addictions Program | Durham | North Carolina | 27705 | — |
| Pahl Pharmaceutical Research, LLC | Oklahoma City | Oklahoma | 73118 | — |
| University of Pennsylvania, Treatment Research Center | Philadelphia | Pennsylvania | 19104 | — |
| Providence Behavioral Health Services | Everett | Washington | 98201-1067 | — |
| Puget Sound Health CareSystem | Seattle | Washington | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00630201, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 31, 2018 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00630201 live on ClinicalTrials.gov.