Long Term Administration of Inhaled Mannitol in Cystic Fibrosis
Public ClinicalTrials.gov record NCT00630812. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Long Term Administration of Inhaled Mannitol in Cystic Fibrosis- A Safety and Efficacy Study
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to examine the efficacy and safety of 26 weeks treatment with inhaled mannitol in subjects with cystic fibrosis. Previous studies have demonstrated improvements in lung function, mucociliary clearance, changes in physical properties of mucus, 24 hour sputum weight and quality of life. The results of this study are to further investigate and confirm these findings in addition to examine the effect on antibiotic use and chest infections. It is hypothesised that inhaled mannitol will have beneficial effects compared to a control treatment. An open label phase of 26 weeks duration will follow the blinded 26 week phase. During the open label phase all subjects will receive active treatment.
Study identification
- NCT ID
- NCT00630812
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 318 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 6 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2008 (Type not available)
- Primary completion
- Apr 2010 (Actual)
- Completion
- Nov 2010 (Actual)
- Last update posted
- Oct 9, 2020
2008 – 2010
United States locations
- U.S. sites
- 28
- U.S. states
- 22
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arizona | Tucson | Arizona | 85724 | — |
| Central Connecticut Cystic Fibrosis Center | Hartford | Connecticut | 66106 | — |
| Nemours Childrens Clinic | Jacksonville | Florida | 32207 | — |
| Batchelor Children's Research Institute - University of Miami | Miami | Florida | 33136 | — |
| Nemours Children's Clinic Orlando | Orlando | Florida | 32801 | — |
| St Lukes CF Center of Idaho | Idaho City | Idaho | 83712 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611 | — |
| Louisiana State University Health Sciences Center | Shreveport | Louisiana | 71130-3932 | — |
| Maine Pediatric Specialty Group | Portland | Maine | 4102 | — |
| John Hopkins | Baltimore | Maryland | 21287 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 62114 | — |
| University of Missouri | Columbia | Missouri | 65212 | — |
| Nebraska Medical Center - Nebraska Regional CF Center | Omaha | Nebraska | 68198-5300 | — |
| Women and Childrens Hospital of Buffalo | Buffalo | New York | 14222 | — |
| The Toledo Hospital and Toledo Childrens Hospital | Toledo | Ohio | 43606 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| St Christopher's Hospital for Children | Philadelphia | Pennsylvania | 19134 | — |
| Medical University of SC | Charleston | South Carolina | 29425 | — |
| Sanford Children's Specialty Clinic | Sioux Falls | South Dakota | 57117 | — |
| Le Bonheur Children's Medical Center | Memphis | Tennessee | 38105 | — |
| Children's Chest Associates of Austin | Austin | Texas | 78723 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Alamo Clinical Research Associates | San Antonio | Texas | 78212 | — |
| Christus Santa Rosa Children's Hospital Cystic Fibrosis Center | San Antonio | Texas | 78229-3900 | — |
| Pediatric Research, VCU Medical Centre | Richmond | Virginia | 23298 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
| University of Washington medical centre | Seattle | Washington | 58103 | — |
| University of Wisconsin | Madison | Wisconsin | 53972 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 25 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00630812, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 9, 2020 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00630812 live on ClinicalTrials.gov.