Open-label Leucovorin Pharmacokinetic Study in Patients Receiving High Dose Methotrexate With or Without Voraxaze
Public ClinicalTrials.gov record NCT00634504. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label Study to Assess the Pharmacokinetics of Leucovorin in Patients Receiving High Dose Methotrexate, With or Without Voraxaze Treatment
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to investigate whether the administration of Voraxaze reduces exposure to leucovorin and its active metabolite to below the level achieved in patients who have not received Voraxaze.
Study identification
- NCT ID
- NCT00634504
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 20 participants
Conditions and interventions
Conditions
Interventions
Drug
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2008 (Type not available)
- Primary completion
- Aug 2009 (Actual)
- Completion
- Aug 2009 (Actual)
- Last update posted
- Jun 6, 2022
2008 – 2009
United States locations
- U.S. sites
- 25
- U.S. states
- 19
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Phoenix Children's Hospital | Phoenix | Arizona | 85016 | — |
| Good Samaritan Hospital | Los Angeles | California | 90017 | — |
| Children's Hospital of Los Angeles | Los Angeles | California | 90027 | — |
| Children's Hospital of Orange County | Los Angeles | California | 92868 | — |
| Oakland's Children's Hospital | Oakland | California | 94609 | — |
| Stanford University Medical Center & Lucile Packard Children's Hospital | Palo Alto | California | 94304-1812 | — |
| California Pacific Medical Center | San Francisco | California | 94115 | — |
| Children's Hospital for Cancer & Blood Disorders | Aurora | Colorado | 80045 | — |
| St. Joseph's Hospital | Tampa | Florida | 33607 | — |
| NorthShore University Health System | Evanston | Illinois | 60201 | — |
| Riley Hospital for Children | Indianapolis | Indiana | 46202 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| University of Massachusetts - Umass Memorial Medical Center | Worcester | Massachusetts | 04655 | — |
| University of MS Medical Center | Jackson | Mississippi | 39216 | — |
| University of Missouri-Columbia | Columbia | Missouri | 65212 | — |
| Washington University Medical Center | St Louis | Missouri | 63110 | — |
| St. Elizabeth Regional Medical Center | Lincoln | Nebraska | 68506 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| ECU Brody School of Medicine | Greenville | North Carolina | 27834 | — |
| Gabrail Cancer Center | Canton | Ohio | 44718 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| St. Jude Children's Research Hospital | Memphis | Tennessee | 38105 | — |
| Texas Children's Hospital | Houston | Texas | 77030 | — |
| Huntsman Cancer Center | Salt Lake City | Utah | 84112 | — |
| Children's Hospital and Regional Medical Center | Seattle | Washington | 98105 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00634504, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 6, 2022 · Synced Nov 1, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00634504 live on ClinicalTrials.gov.