A Randomized Study of Amplimexon (Imexon) With Gemcitabine in Pancreatic Cancer
Public ClinicalTrials.gov record NCT00637247. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Randomized, Double-Blind, Multicenter Trial of Amplimexon® Plus Gemcitabine Versus Gemcitabine Plus Placebo in Patients With Metastatic Chemotherapy Naïve Pancreatic Adenocarcinoma (Stage IV)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine if imexon in combination with gemcitabine could improve overall survival as compared to gemcitabine alone in subjects with pancreatic cancer that has spread to other organs such as the liver or lungs. The study will also look at the safety of the combination as compared to gemcitabine alone. Participants in the study will be randomly assigned to either treatment and neither the participant or their doctors will know which treatment they will be receiving.
Study identification
- NCT ID
- NCT00637247
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 142 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2008 (Actual)
- Primary completion
- May 2010 (Actual)
- Completion
- Jun 2010 (Actual)
- Last update posted
- Mar 20, 2019
2008 – 2010
United States locations
- U.S. sites
- 48
- U.S. states
- 22
- U.S. cities
- 44
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Birmingham Hematology and Oncology- US Oncology | Birmingham | Alabama | 35205 | — |
| AZ Onc Associates D.B.A. Hematology Oncology- US Oncology | Tucson | Arizona | 85704 | — |
| Arizona Clinical Research Center | Tucson | Arizona | 85715 | — |
| Rocky Mountain Cancer Center- US Oncology | Denver | Colorado | 80218 | — |
| Ocala Oncology Center- US Oncology | Ocala | Florida | 34471 | — |
| Cancer Centers of Florida- US Oncology | Orlando | Florida | 34761 | — |
| Peachtree Hematology and Oncology Consultants | Atlanta | Georgia | 30309 | — |
| Hematology Oncology Associates of Illinois- US Oncology | Chicago | Illinois | 60611 | — |
| Cancer Care & Hematolog Specialists of Chicagoland- US Oncology | Niles | Illinois | 60714 | — |
| Central Indiana Cancer Centers- US Oncology | Indianapolis | Indiana | 46227 | — |
| Northern Indiana Cancer Research Consortium | South Bend | Indiana | 46601 | — |
| Hope Center- US Oncology | Terre Haute | Indiana | 47802 | — |
| University of Kentucky, Hematology/Oncology/BMT Clinical Research | Lexington | Kentucky | 40536-0093 | — |
| Lahey Clinic | Burlington | Massachusetts | 01805 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Kansas City Cancer Center, LLC- US Oncology | Kansas City | Missouri | 64131 | — |
| Comprehensive Cancer Centers of Nevada- US Oncology | Las Vegas | Nevada | 89169 | — |
| Hunterdon Regional Cancer Center | Flemington | New Jersey | 08822 | — |
| Hematology Oncology Associates | Mount Holly | New Jersey | 08060 | — |
| Hematology Oncology Associates | Albuquerque | New Mexico | 87106 | — |
| University of New Mexico | Albuquerque | New Mexico | 87131 | — |
| University of New Mexico Cancer Center South | Las Cruces | New Mexico | 88011 | — |
| New Mexico Cancer Care Associates- US Oncology | Santa Fe | New Mexico | 87505 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | — |
| Cancer Center of North Carolina- US Oncology | Raleigh | North Carolina | 27607 | — |
| Medical Onc Assoc of Wyoming Valley, PC- US Oncology | Kingston | Pennsylvania | 18704 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| University of Pittsburgh Cancer Institute | Pittsburgh | Pennsylvania | 15232 | — |
| Pottstown Memorial Medical Center | Pottstown | Pennsylvania | 19464 | — |
| Associates in Hematology-Oncology P.C. US Oncology | Upland | Pennsylvania | 19013 | — |
| Reading Hospital Regional Medical Center | West Reading | Pennsylvania | 19611 | — |
| Sanford Clinic | Sioux Falls | South Dakota | 57104 | — |
| Texas Oncology - Amarillo- US Oncology | Amarillo | Texas | 79106 | — |
| Mamie Mcfaddin Ward Cancer Center, Texas Oncology- US Oncology | Beaumont | Texas | 77702 | — |
| Texas Oncology P.A.- Bedford- US Oncology | Bedford | Texas | 76022 | — |
| Texas Cancer Center at Medical City- US Oncology | Dallas | Texas | 75230 | — |
| Texas Oncology P.A. - Dallas- US Oncology | Dallas | Texas | 75231 | — |
| Methodist Charlton Cancer Center - Texas Oncology- US Oncology | Dallas | Texas | 75237 | — |
| Texas Oncology - Odessa- US Oncology | Odessa | Texas | 79761 | — |
| Scott and White Hospital and Clinics | Temple | Texas | 76508 | — |
| Texas Oncology Cancer Care and Research Center- US Oncology | Waco | Texas | 76712 | — |
| Texoma Cancer Center- US Oncology | Wichita Falls | Texas | 76310 | — |
| Virginia Oncology Associates- US Oncology | Norfolk | Virginia | 23502 | — |
| Onc & Hematology Assoc. of Southern VA, Inc D.B.A. - US Oncology | Salem | Virginia | 24153 | — |
| Swedish Cancer Institute | Seattle | Washington | 98104 | — |
| Cancer Care Northwest- US Oncology | Spokane | Washington | 99202 | — |
| Northwest Cancer Specialists- US Oncology | Vancouver | Washington | 98684 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00637247, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 20, 2019 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00637247 live on ClinicalTrials.gov.