A Study to Compare the Glycemic Effects, Safety, and Tolerability of Exenatide Once Weekly to Those of Sitagliptin and Pioglitazone,in Subjects With Type 2 Diabetes Treated With Metformin (DURATION - 2)
Public ClinicalTrials.gov record NCT00637273. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Parallel-Group, Multicenter Study to Compare the Glycemic Effects, Safety, and Tolerability of Exenatide Long-Acting Release(Once Weekly) to Those of Sitagliptin and a Thiazolidinedione in Subjects With Type 2 Diabetes Mellitus Treated With Metformin
Study identification
- NCT ID
- NCT00637273
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- AstraZeneca
- Industry
- Enrollment
- 514 participants
Conditions and interventions
Conditions
Interventions
- exenatide once weekly Drug
- sitagliptin Drug
- pioglitazone Drug
- placebo tablet Drug
- placebo once weekly Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 31, 2007
- Primary completion
- Jan 31, 2009
- Completion
- Jun 30, 2009
- Last update posted
- Apr 6, 2015
2008 – 2009
United States locations
- U.S. sites
- 51
- U.S. states
- 27
- U.S. cities
- 51
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Peoria | Arizona | — | — |
| Research Site | Artesia | California | — | — |
| Research Site | Concord | California | — | — |
| Research Site | Encino | California | — | — |
| Research Site | Greenbrae | California | — | — |
| Research Site | La Mesa | California | — | — |
| Research Site | Orange | California | — | — |
| Research Site | Walnut Creek | California | — | — |
| Research Site | Whittier | California | — | — |
| Research Site | Colorado Springs | Colorado | — | — |
| Research Site | Washington D.C. | District of Columbia | — | — |
| Research Site | Coral Gables | Florida | — | — |
| Research Site | DeLand | Florida | — | — |
| Research Site | Melbourne | Florida | — | — |
| Research Site | Miami | Florida | — | — |
| Research Site | New Port Richey | Florida | — | — |
| Research Site | Decatur | Georgia | — | — |
| Research Site | Avon | Indiana | — | — |
| Research Site | Wichita | Kansas | — | — |
| Research Site | Paducah | Kentucky | — | — |
| Research Site | Baton Rouge | Louisiana | — | — |
| Research Site | New Orleans | Louisiana | — | — |
| Research Site | Oxon Hill | Maryland | — | — |
| Research Site | Boston | Massachusetts | — | — |
| Research Site | Chelsea | Michigan | — | — |
| Research Site | Ypsilanti | Michigan | — | — |
| Research Site | Saint Louis Park | Minnesota | — | — |
| Research Site | St Louis | Missouri | — | — |
| Research Site | Butte | Montana | — | — |
| Research Site | Lincoln | Nebraska | — | — |
| Research Site | Las Vegas | Nevada | — | — |
| Research Site | New Hyde Park | New York | — | — |
| Research Site | New Windsor | New York | — | — |
| Research Site | New York | New York | — | — |
| Research Site | Rochester | New York | — | — |
| Research Site | Durham | North Carolina | — | — |
| Research Site | Statesville | North Carolina | — | — |
| Research Site | Winston-Salem | North Carolina | — | — |
| Research Site | Athens | Ohio | — | — |
| Research Site | Cincinnati | Ohio | — | — |
| Research Site | Dayton | Ohio | — | — |
| Research Site | Philadelphia | Pennsylvania | — | — |
| Research Site | Rapid City | South Dakota | — | — |
| Research Site | Memphis | Tennessee | — | — |
| Research Site | Austin | Texas | — | — |
| Research Site | Dallas | Texas | — | — |
| Research Site | San Antonio | Texas | — | — |
| Research Site | Richmond | Virginia | — | — |
| Research Site | Olympia | Washington | — | — |
| Research Site | Spokane | Washington | — | — |
| Research Site | Tacoma | Washington | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00637273, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 6, 2015 · Synced Jul 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00637273 live on ClinicalTrials.gov.