Efficacy and Safety of TAK-442 in Subjects Undergoing Total Knee Replacement
Public ClinicalTrials.gov record NCT00641732. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Active Comparator-Controlled, Dose-Ranging Study to Evaluate the Efficacy and Safety of TAK-442 in Subjects Undergoing Total Knee Replacement
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine if TAK-442, once daily (QD) or twice daily (BID), is as safe and effective as enoxaparin in preventing the development of blood clots after knee replacement surgery.
Study identification
- NCT ID
- NCT00641732
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 1,045 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 30, 2007
- Primary completion
- Sep 30, 2008
- Completion
- Sep 30, 2008
- Last update posted
- Apr 12, 2016
2007 – 2008
United States locations
- U.S. sites
- 38
- U.S. states
- 17
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Birmingham | Alabama | — | — |
| Not listed | Tuscaloosa | Alabama | — | — |
| Not listed | Phoenix | Arizona | — | — |
| Not listed | Little Rock | Arkansas | — | — |
| Not listed | Bakersfield | California | — | — |
| Not listed | Fountain Valley | California | — | — |
| Not listed | Long Beach | California | — | — |
| Not listed | Montclair | California | — | — |
| Not listed | Oceanside | California | — | — |
| Not listed | Vista | California | — | — |
| Not listed | Yuba City | California | — | — |
| Not listed | Aurora | Colorado | — | — |
| Not listed | Centennial | Colorado | — | — |
| Not listed | Denver | Colorado | — | — |
| Not listed | Bay Pines | Florida | — | — |
| Not listed | Clearwater | Florida | — | — |
| Not listed | DeLand | Florida | — | — |
| Not listed | Gulf Breeze | Florida | — | — |
| Not listed | Hollywood | Florida | — | — |
| Not listed | Pinellas Park | Florida | — | — |
| Not listed | Tamarac | Florida | — | — |
| Not listed | Atlanta | Georgia | — | — |
| Not listed | Boise | Idaho | — | — |
| Not listed | Meridian | Idaho | — | — |
| Not listed | Springfield | Illinois | — | — |
| Not listed | Towson | Maryland | — | — |
| Not listed | Charlotte | North Carolina | — | — |
| Not listed | Greensboro | North Carolina | — | — |
| Not listed | Cincinnati | Ohio | — | — |
| Not listed | Tulsa | Oklahoma | — | — |
| Not listed | Altoona | Pennsylvania | — | — |
| Not listed | Johnstown | Pennsylvania | — | — |
| Not listed | Charleston | South Carolina | — | — |
| Not listed | Dallas | Texas | — | — |
| Not listed | Grapenne | Texas | — | — |
| Not listed | Lubbock | Texas | — | — |
| Not listed | San Antonio | Texas | — | — |
| Not listed | Spokane | Washington | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 26 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00641732, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 12, 2016 · Synced Sep 1, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00641732 live on ClinicalTrials.gov.