Independent directory Public ClinicalTrials.gov records United States
ClinicalTrials.gov record
Completed Phase 3 Interventional Results available

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Active Systemic Juvenile Idiopathic Arthritis (JIA)

ClinicalTrials.gov ID: NCT00642460

Public ClinicalTrials.gov record NCT00642460. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 2:58 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Placebo-controlled Study to Evaluate the Effect of Tocilizumab on Disease Response in Patients With Active Systemic Juvenile Idiopathic Arthritis (JIA), With an Open-label Extension to Examine the Long Term Use of Tocilizumab

Study identification

NCT ID
NCT00642460
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
112 participants

Conditions and interventions

Interventions

  • tocilizumab [RoActemra/Actemra] Drug
  • Placebo Drug
  • Non-steroidal anti-inflammatory drugs (NSAIDs) Drug
  • methotrexate Drug
  • corticosteroids Drug

Drug

Eligibility (public fields only)

Age range
2 Years to 17 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 30, 2008
Primary completion
Aug 31, 2009
Completion
Jul 31, 2014
Last update posted
Jul 24, 2016

2008 – 2014

United States locations

U.S. sites
13
U.S. states
11
U.S. cities
13
Facility City State ZIP Site status
Not listed Little Rock Arkansas 45229-3039
Not listed Los Angeles California 90027
Not listed Hartford Connecticut 06106
Not listed Augusta Georgia 30912
Not listed Chicago Illinois
Not listed Louisville Kentucky 40202-3906
Not listed Hackensack New Jersey 07601
Not listed Livingston New Jersey 07039
Not listed Durham North Carolina 27710
Not listed Cincinnati Ohio 45229
Not listed Cleveland Ohio 44195
Not listed Oklahoma City Oklahoma 73104
Not listed Houston Texas 77030

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 41 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00642460, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 24, 2016 · Synced Jul 22, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00642460 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →