A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Levofloxacin for the Treatment of Sinus Infections in Adults
Public ClinicalTrials.gov record NCT00643409. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-Blind, Double-Dummy Comparative Trial of Azithromycin SR Versus Levofloxacin for the Treatment of Acute Bacterial Maxillary Sinusitis in Adults Undergoing Diagnostic Sinus Aspiration
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objectives of the study were to confirm that a single, 2.0-g dose of azithromycin sustained release (SR) was at least as effective to 10 days of oral levofloxacin 500 mg once a day, when used to treat adults with uncomplicated, acute bacterial sinus infections, and to evaluate the safety of both treatments.
Study identification
- NCT ID
- NCT00643409
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 541 participants
Conditions and interventions
Conditions
Interventions
- azithromycin SR (Zithromax; compound: CP-62,993) Drug
- placebo Other
- levofloxacin Drug
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2003 (Type not available)
- Primary completion
- Not listed
- Completion
- Feb 2004 (Actual)
- Last update posted
- May 11, 2011
2003 – 2004
United States locations
- U.S. sites
- 59
- U.S. states
- 18
- U.S. cities
- 40
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pfizer Investigational Site | Alabaster | Alabama | 35007 | — |
| Pfizer Investigational Site | Birmingham | Alabama | 35205 | — |
| Pfizer Investigational Site | Birmingham | Alabama | 35211 | — |
| Pfizer Investigational Site | Birmingham | Alabama | 35233 | — |
| Pfizer Investigational Site | Hueytown | Alabama | 35023 | — |
| Pfizer Investigational Site | Montgomery | Alabama | 36106 | — |
| Pfizer Investigational Site | Montgomery | Alabama | 36109 | — |
| Pfizer Investigational Site | Pelham | Alabama | 35124 | — |
| Pfizer Investigational Site | Tuscaloosa | Alabama | 35404 | — |
| Pfizer Investigational Site | Tuscaloosa | Alabama | 35406 | — |
| Pfizer Investigational Site | Jonesboro | Arkansas | 72401 | — |
| Pfizer Investigational Site | Clovis | California | 93611 | — |
| Pfizer Investigational Site | Fresno | California | 93710 | — |
| Pfizer Investigational Site | Fresno | California | 93720 | — |
| Pfizer Investigational Site | San Diego | California | 92103 | — |
| Pfizer Investigational Site | San Diego | California | 92117 | — |
| Pfizer Investigational Site | San Diego | California | 92123 | — |
| Pfizer Investigational Site | Bridgeport | Connecticut | 06606 | — |
| Pfizer Investigational Site | Wichita | Kansas | 67208 | — |
| Pfizer Investigational Site | Louisville | Kentucky | 40207 | — |
| Pfizer Investigational Site | New Orleans | Louisiana | 70115 | — |
| Pfizer Investigational Site | Kalamazoo | Michigan | 49008 | — |
| Pfizer Investigational Site | Portage | Michigan | 49024 | — |
| Pfizer Investigational Site | Richland | Michigan | 49083 | — |
| Pfizer Investigational Site | Three Rivers | Michigan | 49093 | — |
| Pfizer Investigational Site | Jefferson City | Missouri | 65101 | — |
| Pfizer Investigational Site | Missoula | Montana | 59801 | — |
| Pfizer Investigational Site | Missoula | Montana | 59804 | — |
| Pfizer Investigational Site | Charlote | North Carolina | 28210 | — |
| Pfizer Investigational Site | Charlotte | North Carolina | 28210 | — |
| Pfizer Investigational Site | Cincinnati | Ohio | 45241 | — |
| Pfizer Investigational Site | Cincinnati | Ohio | 45242 | — |
| Pfizer Investigational Site | Dayton | Ohio | 45402 | — |
| Pfizer Investigational Site | Dayton | Ohio | 45406 | — |
| Pfizer Investigational Site | Eugene | Oregon | 97401 | — |
| Pfizer Investigational Site | Eugene | Oregon | 97404 | — |
| Pfizer Investigational Site | Medford | Oregon | 97504 | — |
| Pfizer Investigational Site | Morrisville | Pennsylvania | 19067 | — |
| Pfizer Investigational Site | Norristown | Pennsylvania | 19401 | — |
| Pfizer Investigational Site | Plymouth Meeting | Pennsylvania | 19462 | — |
| Pfizer Investigational Site | Orangeburg | South Carolina | 29118 | — |
| Pfizer Investigational Site | Nashville | Tennessee | 37203 | — |
| Pfizer Investigational Site | Amarillo | Texas | 79109 | — |
| Pfizer Investigational Site | Amarillo | Texas | 79119 | — |
| Pfizer Investigational Site | Amarillo | Texas | 79124 | — |
| Pfizer Investigational Site | Bryan | Texas | 77802 | — |
| Pfizer Investigational Site | El Paso | Texas | 79902 | — |
| Pfizer Investigational Site | Houston | Texas | 77015 | — |
| Pfizer Investigational Site | Houston | Texas | 77074 | — |
| Pfizer Investigational Site | Pasadena | Texas | 77505 | — |
| Pfizer Investigational Site | San Antonio | Texas | 78205 | — |
| Pfizer Investigational Site | San Antonio | Texas | 78224 | — |
| Pfizer Investigational Site | San Antonio | Texas | 78229 | — |
| Pfizer Investigational Site | Wichita Falls | Texas | 76302 | — |
| Pfizer Investigational Site | Wichita Falls | Texas | 76309 | — |
| Pfizer Investigational Site | Murray | Utah | 84107 | — |
| Pfizer Investigational Site | Salt Lake City | Utah | 84102 | — |
| Pfizer Investigational Site | Salt Lake City | Utah | 84109 | — |
| Pfizer Investigational Site | Salt Lake City | Utah | 84121 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 30 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00643409, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 11, 2011 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00643409 live on ClinicalTrials.gov.