Effectiveness and Safety of BIO-11006 Inhalation Solution to Treat the Overproduction of Mucus and Inflammation in COPD
Public ClinicalTrials.gov record NCT00648245. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a, Double Blind, Placebo Controlled, Multicenter, Dose Escalation Study to Evaluate the Safety and Efficacy of BIO 11006 Inhalation Solution in Subjects With Chronic Obstructive Pulmonary Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The symptoms associated with COPD include overproduction of mucus and inflammation in the lungs. Overproduction of mucus results in impaired lung function and it encourages bacterial growth and associated COPD exacerbations. Therefore, a treatment that inhibits mucus overproduction or blocks inflammation could benefit COPD patients. The drug under evaluation in this study, BIO-11006 Inhalation Solution, is a new drug that may inhibit overproduction of mucus and may have important anti-inflammatory properties.
Study identification
- NCT ID
- NCT00648245
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 172 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 45 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2008
- Primary completion
- Jun 30, 2010
- Completion
- Jun 30, 2010
- Last update posted
- Feb 9, 2011
2008 – 2010
United States locations
- U.S. sites
- 14
- U.S. states
- 9
- U.S. cities
- 13
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pulmonary Associates | Glendale | Arizona | 85306 | — |
| Greater Los Angeles Healthcare System | Los Angeles | California | 91343 | — |
| Bay Pines VA Heatlhcare System | Bay Pines | Florida | 33744 | — |
| Florida Pulmonary Research Institute, LLC | Winter Park | Florida | 32789 | — |
| Southeastern Lung Care | Decatur | Georgia | 30033 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| VA Sierra Nevada Health Care System | Reno | Nevada | 89502 | — |
| Duke University Medical Center | Durham | North Carolina | 27704 | — |
| North Carolina Clinical Research | Raleigh | North Carolina | 27607 | — |
| Southeastern Research Center, LLC | Winston-Salem | North Carolina | 27103 | — |
| Spartanburg Medical Research | Spartanburg | South Carolina | 29303 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Michael E. DeBakey VAMC | Houston | Texas | 77030 | — |
| Diagnostics Research Group | San Antonio | Texas | 78229 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00648245, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 9, 2011 · Synced Sep 7, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00648245 live on ClinicalTrials.gov.