A Phase I Study of ABT-888 in Combination With Conventional Whole Brain Radiation Therapy (WBRT) in Cancer Patients With Brain Metastases
Public ClinicalTrials.gov record NCT00649207. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1 Study Evaluating the Safety, Tolerability and Pharmacokinetics of ABT-888 in Combination With Whole Brain Radiation Therapy in Subjects With Brain Metastases
Study identification
- NCT ID
- NCT00649207
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- AbbVie (prior sponsor, Abbott)
- Industry
- Enrollment
- 80 participants
Conditions and interventions
Conditions
Interventions
- ABT-888 Drug
- Whole Brain Radiation Therapy Radiation
Drug · Radiation
Eligibility (public fields only)
- Age range
- 18 Years to 99 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 29, 2008
- Primary completion
- Feb 28, 2013
- Completion
- Feb 28, 2013
- Last update posted
- Nov 20, 2017
2008 – 2013
United States locations
- U.S. sites
- 7
- U.S. states
- 7
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Site Reference ID/Investigator# 8334 | Atlanta | Georgia | 30322 | — |
| Site Reference ID/Investigator# 52462 | Chicago | Illinois | 60611 | — |
| Site Reference ID/Investigator# 24483 | Kansas City | Kansas | 66160 | — |
| Site Reference ID/Investigator# 7180 | Baltimore | Maryland | 21231-2410 | — |
| Site Reference ID/Investigator# 19021 | Detroit | Michigan | 48202-2689 | — |
| Site Reference ID/Investigator# 6344 | Philadelphia | Pennsylvania | 19111 | — |
| Site Reference ID/Investigator# 6653 | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00649207, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 20, 2017 · Synced Jul 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00649207 live on ClinicalTrials.gov.