Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-angle Glaucoma or Ocular Hypertension
Public ClinicalTrials.gov record NCT00650338. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-masked, Placebo- and Active- Controlled, Parallel-group, Multi-center, Dose-response Trial of DE-104 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension
Study identification
- NCT ID
- NCT00650338
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Santen Inc.
- Industry
- Enrollment
- 165 participants
Conditions and interventions
Conditions
Interventions
- DE-104 ophthalmic solution, low concentration Drug
- DE-104 ophthalmic solution, medium concentration Drug
- DE-104 ophthalmic solution, high concentration Drug
- Placebo Drug
- 0.005% latanoprost Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 29, 2008
- Primary completion
- Aug 31, 2008
- Completion
- Sep 30, 2008
- Last update posted
- Nov 2, 2011
2008
United States locations
- U.S. sites
- 14
- U.S. states
- 9
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Sall Research Medical Center | Artesia | California | 90701 | — |
| USC Department of Ophthalmology | Los Angeles | California | 90033 | — |
| Wolstan Eye Associates | Torrance | California | 90505 | — |
| East Florida Eye Institute | Stuart | Florida | 34994 | — |
| Seidenberg Protzko Eye Associates | Bel Air | Maryland | 21014 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198-5540 | — |
| Rochester Ophthalmological Group, PC | Rochester | New York | 14618 | — |
| Cornerstone Eye Care | High Point | North Carolina | 27262 | — |
| Associated Glaucoma Consultants | Philadelphia | Pennsylvania | 19107 | — |
| Keystone Research, Ltd. | Austin | Texas | 78731 | — |
| David Shulman, MD P-A | San Antonio | Texas | 78209 | — |
| Eye Clinics of South Texas | San Antonio | Texas | 78209 | — |
| Medical Center Ophthalmology Associates | San Antonio | Texas | 78240 | — |
| Virginia Eye Consultants | Norfolk | Virginia | 23507 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00650338, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 2, 2011 · Synced Jul 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00650338 live on ClinicalTrials.gov.