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Completed Phase 2 Interventional Results available

APRiCOT-L: Study to Evaluate Efficacy and Safety of Apricoxib With Erlotinib in Patients With Non-small Cell Lung Cancer

ClinicalTrials.gov ID: NCT00652340

Public ClinicalTrials.gov record NCT00652340. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 22, 2026, 3:54 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

APRiCOT-L (Apricoxib in Combination Oncology Treatment - Lung) A Randomized, Double-Blind, Placebo-Controlled Multicenter Phase 2 Study of the Efficacy and Safety of Apricoxib in Combination With Erlotinib in Non-Small Cell Lung Cancer Patients

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will compare the anti-tumor efficacy of apricoxib and erlotinib with placebo and erlotinib as measured by time to disease progression to test the hypothesis that down regulation of COX-2 and EGFR pathways in patients with up-regulated COX-2 expression in tumor will have a clinical benefit compared with erlotinib alone.

Study identification

NCT ID
NCT00652340
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Tragara Pharmaceuticals, Inc.
Industry
Enrollment
120 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 2008 (Type not available)
Primary completion
Jun 2010 (Actual)
Completion
Mar 2012 (Actual)
Last update posted
Apr 9, 2012

2008 – 2012

United States locations

U.S. sites
47
U.S. states
24
U.S. cities
47
Facility City State ZIP Site status
Not listed Tucson Arizona — —
Not listed Bakersfield California — —
Not listed Los Angeles California — —
Not listed Rancho Mirage California — —
Not listed San Diego California — —
Not listed San Dimas California — —
Not listed Stockton California — —
Not listed Norwich Connecticut — —
Not listed Lake North Florida — —
Not listed Lakeland Florida — —
Not listed Miami Florida — —
Not listed Savannah Georgia — —
Not listed Chicago Illinois — —
Not listed Kokomo Indiana — —
Not listed New Albany Indiana — —
Not listed Waterloo Iowa — —
Not listed Louisville Kentucky — —
Not listed New Orleans Louisiana — —
Not listed Ann Arbor Michigan — —
Not listed Jackson Michigan — —
Not listed Lansing Michigan — —
Not listed Livonia Michigan — —
Not listed Saginaw Michigan — —
Not listed Saint Joseph Michigan — —
Not listed Robbinsdale Minnesota — —
Not listed St Louis Missouri — —
Not listed Neptune City New Jersey — —
Not listed Elmhurst New York — —
Not listed Stony Brook New York — —
Not listed Gastonia North Carolina — —
Not listed Wilmington North Carolina — —
Not listed Akron Ohio — —
Not listed Canton Ohio — —
Not listed Columbus Ohio — —
Not listed Jefferson Ohio — —
Not listed Sylvania Ohio — —
Not listed Corvallis Oregon — —
Not listed Portland Oregon — —
Not listed Upland Pennsylvania — —
Not listed Charleston South Carolina — —
Not listed Arlington Texas — —
Not listed Galveston Texas — —
Not listed Newport News Virginia — —
Not listed Richmond Virginia — —
Not listed Tacoma Washington — —
Not listed Huntington West Virginia — —
Not listed Morgantown West Virginia — —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00652340, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 9, 2012 · Synced Oct 22, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00652340 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →