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Completed Phase 2 Interventional Results available

APRiCOT-L: Study to Evaluate Efficacy and Safety of Apricoxib With Erlotinib in Patients With Non-small Cell Lung Cancer

ClinicalTrials.gov ID: NCT00652340

Public ClinicalTrials.gov record NCT00652340. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 6, 2026, 6:27 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

APRiCOT-L (Apricoxib in Combination Oncology Treatment - Lung) A Randomized, Double-Blind, Placebo-Controlled Multicenter Phase 2 Study of the Efficacy and Safety of Apricoxib in Combination With Erlotinib in Non-Small Cell Lung Cancer Patients

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will compare the anti-tumor efficacy of apricoxib and erlotinib with placebo and erlotinib as measured by time to disease progression to test the hypothesis that down regulation of COX-2 and EGFR pathways in patients with up-regulated COX-2 expression in tumor will have a clinical benefit compared with erlotinib alone.

Study identification

NCT ID
NCT00652340
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Tragara Pharmaceuticals, Inc.
Industry
Enrollment
120 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2008
Primary completion
May 31, 2010
Completion
Feb 29, 2012
Last update posted
Apr 8, 2012

2008 – 2012

United States locations

U.S. sites
47
U.S. states
24
U.S. cities
47
Facility City State ZIP Site status
Not listed Tucson Arizona
Not listed Bakersfield California
Not listed Los Angeles California
Not listed Rancho Mirage California
Not listed San Diego California
Not listed San Dimas California
Not listed Stockton California
Not listed Norwich Connecticut
Not listed Lake North Florida
Not listed Lakeland Florida
Not listed Miami Florida
Not listed Savannah Georgia
Not listed Chicago Illinois
Not listed Kokomo Indiana
Not listed New Albany Indiana
Not listed Waterloo Iowa
Not listed Louisville Kentucky
Not listed New Orleans Louisiana
Not listed Ann Arbor Michigan
Not listed Jackson Michigan
Not listed Lansing Michigan
Not listed Livonia Michigan
Not listed Saginaw Michigan
Not listed Saint Joseph Michigan
Not listed Robbinsdale Minnesota
Not listed St Louis Missouri
Not listed Neptune City New Jersey
Not listed Elmhurst New York
Not listed Stony Brook New York
Not listed Gastonia North Carolina
Not listed Wilmington North Carolina
Not listed Akron Ohio
Not listed Canton Ohio
Not listed Columbus Ohio
Not listed Jefferson Ohio
Not listed Sylvania Ohio
Not listed Corvallis Oregon
Not listed Portland Oregon
Not listed Upland Pennsylvania
Not listed Charleston South Carolina
Not listed Arlington Texas
Not listed Galveston Texas
Not listed Newport News Virginia
Not listed Richmond Virginia
Not listed Tacoma Washington
Not listed Huntington West Virginia
Not listed Morgantown West Virginia

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00652340, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 8, 2012 · Synced Sep 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00652340 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →