ClinicalTrials.gov record
Completed Phase 3 Interventional Results available

Combination Chemotherapy, Radiation Therapy, and an Autologous Peripheral Blood Stem Cell Transplant in Treating Young Patients With Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System

ClinicalTrials.gov ID: NCT00653068

Public ClinicalTrials.gov record NCT00653068. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 29, 2026, 9:19 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Treatment of Atypical Teratoid/Rhabdoid Tumors (AT/RT) of the Central Nervous System With Surgery, Intensive Chemotherapy, and 3-D Conformal Radiation

Study identification

NCT ID
NCT00653068
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Children's Oncology Group
Network
Enrollment
70 participants

Conditions and interventions

Interventions

  • 3-Dimensional Conformal Radiation Therapy Radiation
  • Autologous Hematopoietic Stem Cell Transplantation Procedure
  • Carboplatin Drug
  • Cisplatin Drug
  • Cyclophosphamide Drug
  • Etoposide Drug
  • Filgrastim Biological
  • Laboratory Biomarker Analysis Other
  • Leucovorin Calcium Drug
  • Methotrexate Drug
  • Thiotepa Drug
  • Vincristine Sulfate Drug

Radiation · Procedure · Drug + 2 more

Eligibility (public fields only)

Age range
Up to 21 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 9, 2009
Primary completion
Sep 26, 2016
Completion
Mar 30, 2024
Last update posted
Apr 22, 2024

2009 – 2024

United States locations

U.S. sites
87
U.S. states
35
U.S. cities
75
Facility City State ZIP Site status
Children's Hospital of Alabama Birmingham Alabama 35233
University of Alabama at Birmingham Cancer Center Birmingham Alabama 35233
University of Arkansas for Medical Sciences Little Rock Arkansas 72205
Kaiser Permanente Downey Medical Center Downey California 90242
Miller Children's and Women's Hospital Long Beach Long Beach California 90806
Children's Hospital Los Angeles Los Angeles California 90027
Valley Children's Hospital Madera California 93636
UCSF Benioff Children's Hospital Oakland Oakland California 94609
Children's Hospital of Orange County Orange California 92868
Rady Children's Hospital - San Diego San Diego California 92123
UCSF Medical Center-Parnassus San Francisco California 94143
UCSF Medical Center-Mission Bay San Francisco California 94158
Connecticut Children's Medical Center Hartford Connecticut 06106
Alfred I duPont Hospital for Children Wilmington Delaware 19803
Children's National Medical Center Washington D.C. District of Columbia 20010
Lee Memorial Health System Fort Myers Florida 33901
Golisano Children's Hospital of Southwest Florida Fort Myers Florida 33908
University of Florida Health Science Center - Gainesville Gainesville Florida 32610
Nemours Children's Clinic-Jacksonville Jacksonville Florida 32207
University of Miami Miller School of Medicine-Sylvester Cancer Center Miami Florida 33136
AdventHealth Orlando Orlando Florida 32803
Nemours Children's Clinic - Orlando Orlando Florida 32806
Orlando Health Cancer Institute Orlando Florida 32806
Nemours Children's Clinic - Pensacola Pensacola Florida 32504
Johns Hopkins All Children's Hospital St. Petersburg Florida 33701
Saint Joseph's Hospital/Children's Hospital-Tampa Tampa Florida 33607
Saint Mary's Hospital West Palm Beach Florida 33407
Children's Healthcare of Atlanta - Egleston Atlanta Georgia 30322
University of Hawaii Cancer Center Honolulu Hawaii 96813
Lurie Children's Hospital-Chicago Chicago Illinois 60611
University of Chicago Comprehensive Cancer Center Chicago Illinois 60637
Loyola University Medical Center Maywood Illinois 60153
Riley Hospital for Children Indianapolis Indiana 46202
University of Kentucky/Markey Cancer Center Lexington Kentucky 40536
Norton Children's Hospital Louisville Kentucky 40202
Tulane University School of Medicine New Orleans Louisiana 70112
Children's Hospital New Orleans New Orleans Louisiana 70118
Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore Maryland 21287
Walter Reed National Military Medical Center Bethesda Maryland 20889-5600
Dana-Farber Cancer Institute Boston Massachusetts 02215
Wayne State University/Karmanos Cancer Institute Detroit Michigan 48201
Children's Hospitals and Clinics of Minnesota - Minneapolis Minneapolis Minnesota 55404
Mayo Clinic in Rochester Rochester Minnesota 55905
University of Mississippi Medical Center Jackson Mississippi 39216
Children's Mercy Hospitals and Clinics Kansas City Missouri 64108
Washington University School of Medicine St Louis Missouri 63110
Children's Hospital and Medical Center of Omaha Omaha Nebraska 68114
Hackensack University Medical Center Hackensack New Jersey 07601
Morristown Medical Center Morristown New Jersey 07960
Saint Joseph's Regional Medical Center Paterson New Jersey 07503
Overlook Hospital Summit New Jersey 07902
University of New Mexico Cancer Center Albuquerque New Mexico 87102
Roswell Park Cancer Institute Buffalo New York 14263
Laura and Isaac Perlmutter Cancer Center at NYU Langone New York New York 10016
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center New York New York 10032
Memorial Sloan Kettering Cancer Center New York New York 10065
University of Rochester Rochester New York 14642
Montefiore Medical Center - Moses Campus The Bronx New York 10467
New York Medical College Valhalla New York 10595
Mission Hospital Asheville North Carolina 28801
UNC Lineberger Comprehensive Cancer Center Chapel Hill North Carolina 27599
Carolinas Medical Center/Levine Cancer Institute Charlotte North Carolina 28203
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229
Rainbow Babies and Childrens Hospital Cleveland Ohio 44106
Cleveland Clinic Foundation Cleveland Ohio 44195
Nationwide Children's Hospital Columbus Ohio 43205
Dayton Children's Hospital Dayton Ohio 45404
Mercy Children's Hospital Toledo Ohio 43608
University of Oklahoma Health Sciences Center Oklahoma City Oklahoma 73104
Penn State Children's Hospital Hershey Pennsylvania 17033
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104
Rhode Island Hospital Providence Rhode Island 02903
Medical University of South Carolina Charleston South Carolina 29425
Prisma Health Richland Hospital Columbia South Carolina 29203
BI-LO Charities Children's Cancer Center Greenville South Carolina 29605
Greenville Cancer Treatment Center Greenville South Carolina 29605
East Tennessee Childrens Hospital Knoxville Tennessee 37916
Driscoll Children's Hospital Corpus Christi Texas 78411
Cook Children's Medical Center Fort Worth Texas 76104
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center Houston Texas 77030
Methodist Children's Hospital of South Texas San Antonio Texas 78229
University of Texas Health Science Center at San Antonio San Antonio Texas 78229
Primary Children's Hospital Salt Lake City Utah 84113
Seattle Children's Hospital Seattle Washington 98105
West Virginia University Charleston Division Charleston West Virginia 25304
Marshfield Medical Center-Marshfield Marshfield Wisconsin 54449
Children's Hospital of Wisconsin Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00653068, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 22, 2024 · Synced Apr 29, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00653068 live on ClinicalTrials.gov.

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