ClinicalTrials.gov record
Paclitaxel, Cisplatin, and Radiation Therapy With or Without Cetuximab in Treating Patients With Locally Advanced Esophageal Cancer
ClinicalTrials.gov ID: NCT00655876
Public ClinicalTrials.gov record NCT00655876. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 21, 2026, 12:57 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Trial Evaluating the Addition of Cetuximab to Paclitaxel, Cisplatin, and Radiation for Patients With Esophageal Cancer Who Are Treated Without Surgery
Study identification
- NCT ID
- NCT00655876
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Radiation Therapy Oncology Group
- Network
- Enrollment
- 344 participants
Conditions and interventions
Conditions
Interventions
- cetuximab Drug
- cisplatin Drug
- paclitaxel Drug
- radiation therapy Radiation
Drug · Radiation
Eligibility (public fields only)
- Age range
- 18 Years to 74 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2008
- Primary completion
- Mar 31, 2015
- Completion
- May 19, 2022
- Last update posted
- Jun 13, 2022
2008 – 2022
United States locations
- U.S. sites
- 173
- U.S. states
- 41
- U.S. cities
- 143
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Oncology - Tucson | Tucson | Arizona | 85704 | — |
| Auburn Radiation Oncology | Auburn | California | 95603 | — |
| Radiation Oncology Centers - Cameron Park | Cameron Park | California | 95682 | — |
| Mercy Cancer Center at Mercy San Juan Medical Center | Carmichael | California | 95608 | — |
| Enloe Cancer Center at Enloe Medical Center | Chico | California | 95926 | — |
| California Cancer Center - Woodward Park Office | Fresno | California | 93720 | — |
| Saint Agnes Cancer Center at Saint Agnes Medical Center | Fresno | California | 93720 | — |
| Memorial Medical Center | Modesto | California | 95355 | — |
| Radiation Oncology Center - Roseville | Roseville | California | 95661 | — |
| Radiological Associates of Sacramento Medical Group, Incorporated | Sacramento | California | 95815 | — |
| University of California Davis Cancer Center | Sacramento | California | 95817 | — |
| Mercy General Hospital | Sacramento | California | 95819 | — |
| Solano Radiation Oncology Center | Vacaville | California | 95687 | — |
| Sutter Solano Medical Center | Vallejo | California | 94589 | — |
| Rocky Mountain Cancer Centers - Aurora | Aurora | Colorado | 80012 | — |
| Porter Adventist Hospital | Denver | Colorado | 80210 | — |
| George Bray Cancer Center at the Hospital of Central Connecticut - New Britain Campus | New Britain | Connecticut | 06050 | — |
| William W. Backus Hospital | Norwich | Connecticut | 06360 | — |
| CCOP - Christiana Care Health Services | Newark | Delaware | 19713 | — |
| University of Florida Shands Cancer Center | Gainesville | Florida | 32610-0232 | — |
| Ella Milbank Foshay Cancer Center at Jupiter Medical Center | Jupiter | Florida | 33458 | — |
| Center for Cancer Care and Research at Watson Clinic, LLP | Lakeland | Florida | 33805 | — |
| Baptist-South Miami Regional Cancer Program | Miami | Florida | 33176 | — |
| CCOP - Mount Sinai Medical Center | Miami Beach | Florida | 33140 | — |
| M.D. Anderson Cancer Center at Orlando | Orlando | Florida | 32806 | — |
| John B. Amos Cancer Center | Columbus | Georgia | 31904 | — |
| Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler | Savannah | Georgia | 31405 | — |
| Cancer Research Center of Hawaii | Honolulu | Hawaii | 96813 | — |
| Queen's Cancer Institute at Queen's Medical Center | Honolulu | Hawaii | 96813 | — |
| Hawaii Medical Center - East | Honolulu | Hawaii | 96817 | — |
| Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center | Boise | Idaho | 83706 | — |
| Robert H. Lurie Comprehensive Cancer Center at Northwestern University | Chicago | Illinois | 60611-3013 | — |
| University of Chicago Cancer Research Center | Chicago | Illinois | 60637-1470 | — |
| Cardinal Bernardin Cancer Center at Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| Advocate Lutheran General Cancer Care Center | Park Ridge | Illinois | 60068-1174 | — |
| Swedish-American Regional Cancer Center | Rockford | Illinois | 61104-2315 | — |
| Cancer Institute at St. John's Hospital | Springfield | Illinois | 62702 | — |
| Saint John's Cancer Center at Saint John's Medical Center | Anderson | Indiana | 46016 | — |
| Bloomington Hospital Regional Cancer Institute | Bloomington | Indiana | 47403 | — |
| Radiation Oncology Associates Southwest | Fort Wayne | Indiana | 46804 | — |
| Parkview Regional Cancer Center at Parkview Health | Fort Wayne | Indiana | 46805 | — |
| Methodist Cancer Center at Methodist Hospital | Indianapolis | Indiana | 46202 | — |
| Central Indiana Cancer Centers - East | Indianapolis | Indiana | 46219 | — |
| Cancer Center at Ball Memorial Hospital | Muncie | Indiana | 47303-3499 | — |
| Memorial Hospital of South Bend | South Bend | Indiana | 46601 | — |
| McFarland Clinic, PC | Ames | Iowa | 50010 | — |
| John Stoddard Cancer Center at Iowa Methodist Medical Center | Des Moines | Iowa | 50309 | — |
| Mercy Cancer Center at Mercy Medical Center - Des Moines | Des Moines | Iowa | 50314 | — |
| Mercy Cancer Center at Mercy Medical Center - North Iowa | Mason City | Iowa | 50401 | — |
| Siouxland Hematology-Oncology Associates, LLP | Sioux City | Iowa | 51101 | — |
| James Graham Brown Cancer Center at University of Louisville | Louisville | Kentucky | 40202 | — |
| Mary Bird Perkins Cancer Center - Baton Rouge | Baton Rouge | Louisiana | 70809 | — |
| Greenebaum Cancer Center at University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Greater Baltimore Medical Center Cancer Center | Baltimore | Maryland | 21204 | — |
| St. Agnes Hospital Cancer Center | Baltimore | Maryland | 21229 | — |
| Hudner Oncology Center at Saint Anne's Hospital - Fall River | Fall River | Massachusetts | 02721 | — |
| Saint Joseph Mercy Cancer Center | Ann Arbor | Michigan | 48106-0995 | — |
| Josephine Ford Cancer Center at Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Genesys Hurley Cancer Institute | Flint | Michigan | 48503 | — |
| Lacks Cancer Center at Saint Mary's Health Care | Grand Rapids | Michigan | 49503 | — |
| Van Elslander Cancer Center at St. John Hospital and Medical Center | Grosse Pointe Woods | Michigan | 48236 | — |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007-3731 | — |
| St. Mary Mercy Hospital | Livonia | Michigan | 48154 | — |
| Mercy Regional Cancer Center at Mercy Hospital | Port Huron | Michigan | 48060 | — |
| Seton Cancer Institute at Saint Mary's - Saginaw | Saginaw | Michigan | 48601 | — |
| MeritCare Bemidji | Bemidji | Minnesota | 56601 | — |
| Mercy and Unity Cancer Center at Mercy Hospital | Coon Rapids | Minnesota | 55433 | — |
| Minnesota Oncology - Maplewood | Maplewood | Minnesota | 55109 | — |
| Regions Hospital Cancer Care Center | Saint Paul | Minnesota | 55101 | — |
| United Hospital | Saint Paul | Minnesota | 55102 | — |
| University of Mississippi Cancer Clinic | Jackson | Mississippi | 39216 | — |
| Cancer Institute of Cape Girardeau, LLC | Cape Girardeau | Missouri | 63703 | — |
| Saint Louis University Cancer Center | St Louis | Missouri | 63110 | — |
| Missouri Baptist Cancer Center | St Louis | Missouri | 63131 | — |
| David C. Pratt Cancer Center at St. John's Mercy | St Louis | Missouri | 63141 | — |
| Billings Clinic - Downtown | Billings | Montana | 59107-7000 | — |
| Sletten Cancer Institute at Benefis Healthcare | Great Falls | Montana | 59405 | — |
| Methodist Estabrook Cancer Center | Omaha | Nebraska | 68114 | — |
| Lakeside Hospital | Omaha | Nebraska | 68130 | — |
| CCOP - Nevada Cancer Research Foundation | Las Vegas | Nevada | 89106 | — |
| Payson Center for Cancer Care at Concord Hospital | Concord | New Hampshire | 03301 | — |
| Seacoast Cancer Center at Wentworth - Douglass Hospital | Dover | New Hampshire | 03820 | — |
| Center for Cancer Care at Exeter Hospital | Exeter | New Hampshire | 03833 | — |
| Kingsbury Center for Cancer Care at Cheshire Medical Center | Keene | New Hampshire | 03431 | — |
| Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756-0002 | — |
| Elliot Regional Cancer Center at Elliot Hospital | Manchester | New Hampshire | 03103 | — |
| Monmouth Medical Center | Long Branch | New Jersey | 07740-6395 | — |
| Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital Marlton | Marlton | New Jersey | 08053 | — |
| Frederick R. and Betty M. Smith Cancer Treatment Center | Sparta | New Jersey | 07871 | — |
| J. Phillip Citta Regional Cancer Center at Community Medical Center | Toms River | New Jersey | 08755 | — |
| Cancer Institute of New Jersey at Cooper - Voorhees | Voorhees Township | New Jersey | 08043 | — |
| New York Oncology Hematology, PC at Albany Regional Cancer Care | Albany | New York | 12206 | — |
| Lourdes Regional Cancer Center | Binghamton | New York | 13905 | — |
| Charles R. Wood Cancer Center at Glens Falls Hospital | Glens Falls | New York | 12801 | — |
| Beth Israel Medical Center - Petrie Division | New York | New York | 10003-3803 | — |
| St. Luke's - Roosevelt Hospital Center - St.Luke's Division | New York | New York | 10025 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10065 | — |
| Memorial Sloan-Kettering Cancer Center at Phelps Memorial Hospital Center | Sleepy Hollow | New York | 10591 | — |
| Mission Hospitals - Memorial Campus | Asheville | North Carolina | 28801 | — |
| Alamance Cancer Center at Alamance Regional Medical Center | Burlington | North Carolina | 27216 | — |
| Presbyterian Cancer Center at Presbyterian Hospital | Charlotte | North Carolina | 28233-3549 | — |
| Kinston Medical Specialists | Kinston | North Carolina | 28501 | — |
| CCOP - MeritCare Hospital | Fargo | North Dakota | 58122 | — |
| McDowell Cancer Center at Akron General Medical Center | Akron | Ohio | 44307 | — |
| Summa Center for Cancer Care at Akron City Hospital | Akron | Ohio | 44309-2090 | — |
| Barberton Citizens Hospital | Barberton | Ohio | 44203 | — |
| Mercy Cancer Center at Mercy Medical Center | Canton | Ohio | 44708 | — |
| Aultman Cancer Center at Aultman Hospital | Canton | Ohio | 44710-1799 | — |
| Case Comprehensive Cancer Center | Cleveland | Ohio | 44106-5065 | — |
| MetroHealth Cancer Care Center at MetroHealth Medical Center | Cleveland | Ohio | 44109 | — |
| Lake/University Ireland Cancer Center | Mentor | Ohio | 44060 | — |
| Southwest General Health Center | Middleburg Heights | Ohio | 44130 | — |
| UHHS Chagrin Highlands Medical Center | Orange | Ohio | 44122 | — |
| Robinson Radiation Oncology | Ravenna | Ohio | 44266 | — |
| UHHS Westlake Medical Center | Westlake | Ohio | 44145 | — |
| Oklahoma University Cancer Institute | Oklahoma City | Oklahoma | 73104 | — |
| Natalie Warren Bryant Cancer Center at St. Francis Hospital | Tulsa | Oklahoma | 74136 | — |
| Clackamas Radiation Oncology Center | Clackamas | Oregon | 97015 | — |
| Willamette Valley Cancer Center - Eugene | Eugene | Oregon | 97401 | — |
| Providence Cancer Center at Providence Portland Medical Center | Portland | Oregon | 97213-2967 | — |
| Providence St. Vincent Medical Center | Portland | Oregon | 97225 | — |
| UPMC Cancer Center at Beaver Medical Center | Beaver | Pennsylvania | 15009 | — |
| UPMC Cancer Center at Jefferson Regional Medical Center | Clairton | Pennsylvania | 15025 | — |
| Delaware County Regional Cancer Center at Delaware County Memorial Hospital | Drexel Hill | Pennsylvania | 19026 | — |
| Regional Cancer Center - Erie | Erie | Pennsylvania | 16505 | — |
| Adams Cancer Center | Gettysburg | Pennsylvania | 17325 | — |
| UPMC Cancer Center - Arnold Palmer Pavilion | Greensburg | Pennsylvania | 15601 | — |
| Frankford Hospital Cancer Center - Torresdale Campus | Philadelphia | Pennsylvania | 19114 | — |
| Albert Einstein Cancer Center | Philadelphia | Pennsylvania | 19141 | — |
| UPMC - Shadyside | Pittsburgh | Pennsylvania | 15213-2582 | — |
| UPMC Cancer Center at UPMC St. Margaret | Pittsburgh | Pennsylvania | 15215 | — |
| UPMC Cancer Center at UPMC Passavant | Pittsburgh | Pennsylvania | 15237 | — |
| McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center | Reading | Pennsylvania | 19612-6052 | — |
| UPMC Cancer Center at UPMC Northwest | Seneca | Pennsylvania | 16346 | — |
| York Cancer Center at Apple Hill Medical Center | York | Pennsylvania | 17405 | — |
| Rhode Island Hospital Comprehensive Cancer Center | Providence | Rhode Island | 02903 | — |
| Northmain Radiation Oncology | Providence | Rhode Island | 02904 | — |
| Hollings Cancer Center at Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Cancer Centers of the Carolinas - Faris Road | Greenville | South Carolina | 29605 | — |
| CCOP - Greenville | Greenville | South Carolina | 29615 | — |
| Cancer Centers of the Carolinas - Seneca | Seneca | South Carolina | 29672 | — |
| CCOP - Upstate Carolina | Spartanburg | South Carolina | 29303 | — |
| Gibbs Regional Cancer Center at Spartanburg Regional Medical Center | Spartanburg | South Carolina | 29303 | — |
| Cancer Centers of the Carolinas - Spartanburg | Spartanburg | South Carolina | 29307 | — |
| Rapid City Regional Hospital | Rapid City | South Dakota | 57701 | — |
| Sanford Cancer Center at Sanford USD Medical Center | Sioux Falls | South Dakota | 57117-5039 | — |
| Thompson Cancer Survival Center | Knoxville | Tennessee | 37916 | — |
| Harrington Cancer Center | Amarillo | Texas | 79106 | — |
| Texas Oncology, PA at Harris Center HEB | Bedford | Texas | 76022 | — |
| Texas Oncology, PA at Texas Cancer Center - Denton South | Denton | Texas | 76210 | — |
| Klabzuba Cancer Center at Harris Methodist Fort Worth Hospital | Fort Worth | Texas | 76104 | — |
| Memorial Hermann Hospital - Memorial City | Houston | Texas | 77024 | — |
| Longview Cancer Center | Longview | Texas | 75601 | — |
| Joe Arrington Cancer Research and Treatment Center | Lubbock | Texas | 79410-1894 | — |
| Cancer Care Centers of South Texas - Northeast | San Antonio | Texas | 78217 | — |
| Texas Oncology, PA at Texas Cancer Center - Sherman | Sherman | Texas | 75090 | — |
| Texas Oncology, PA at Texas Oncology Cancer Center Sugar Land | Sugar Land | Texas | 77479 | — |
| Tyler Cancer Center | Tyler | Texas | 75702 | — |
| Texas Oncology, PA - Wichita Falls | Wichita Falls | Texas | 76310 | — |
| Jon and Karen Huntsman Cancer Center at Intermountain Medical Center | Murray | Utah | 84157 | — |
| Utah Cancer Specialists at UCS Cancer Center | Salt Lake City | Utah | 84106 | — |
| Huntsman Cancer Institute at University of Utah | Salt Lake City | Utah | 84112 | — |
| Dixie Regional Medical Center - East Campus | St. George | Utah | 84770 | — |
| Northwest Cancer Specialists at Vancouver Cancer Center | Vancouver | Washington | 98684 | — |
| Schiffler Cancer Center at Wheeling Hospital | Wheeling | West Virginia | 26003 | — |
| St. Mary's Hospital Medical Center - Green Bay | Green Bay | Wisconsin | 54303 | — |
| St. Vincent Hospital Regional Cancer Center | Green Bay | Wisconsin | 54307-3508 | — |
| Bay Area Cancer Care Center at Bay Area Medical Center | Marinette | Wisconsin | 54143 | — |
| Veterans Affairs Medical Center - Milwaukee | Milwaukee | Wisconsin | 53295 | — |
| Regional Cancer Center at Oconomowoc Memorial Hospital | Oconomowoc | Wisconsin | 53066 | — |
| Door County Cancer Center at Door County Memorial Hospital | Sturgeon Bay | Wisconsin | 54235-1495 | — |
| Waukesha Memorial Hospital Regional Cancer Center | Waukesha | Wisconsin | 53188 | — |
| University of Wisconcin Cancer Center at Aspirus Wausau Hospital | Wausau | Wisconsin | 54401 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00655876, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 13, 2022 · Synced May 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00655876 live on ClinicalTrials.gov.