Safety and Efficacy of Sildenafil in Cystic Fibrosis (CF) Lung Disease

ClinicalTrials.gov ID: NCT00659529

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Official title

The Role of Phosphodiesterase Inhibitors in CF Lung Disease

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine whether sildenafil can decrease inflammation in CF lung disease.

Study identification

NCT ID: NCT00659529
Recruitment status: Completed
Study type: Interventional
Phase: Phase 1, Phase 2
Lead sponsor: National Jewish Health; Other
Enrollment: 36 participants

Conditions and interventions

Conditions

Cystic Fibrosis

Interventions

sildenafil Drug

Drug

Eligibility (public fields only)

Age range: 14 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Aug 2008 (Actual)
Primary completion: Aug 2012 (Actual)
Completion: Dec 2012 (Actual)
Last update posted: May 14, 2026

2008 – 2012

United States locations

U.S. sites: 1
U.S. states: 1
U.S. cities: 1

Facility	City	State	ZIP	Site status
National Jewish Health	Denver	Colorado	80206	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT00659529, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted May 14, 2026 · Synced Nov 15, 2026