ClinicalTrials.gov record
S0709: Erlotinib With or Without Carboplatin and Paclitaxel in Stage IIIB or Stage IV Non-Small Cell Lung Cancer
ClinicalTrials.gov ID: NCT00661193
Public ClinicalTrials.gov record NCT00661193. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Selection Design of Pharmacodynamic Separation of Carboplatin/Paclitaxel/OSI-774 (Erlotinib; NSC-718781) or OSI-774 Alone in Advanced Non-Small Cell Lung Cancer (NSCLC) Patients With Performance Status 2 (PS-2)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Erlotinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as carboplatin and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving erlotinib together with carboplatin and paclitaxel may kill more tumor cells. PURPOSE: This randomized phase II trial is studying how well erlotinib works when given alone or together with carboplatin and paclitaxel in treating patients with stage IIIB or stage IV non-small cell lung cancer.
Study identification
- NCT ID
- NCT00661193
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 59 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 120 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 30, 2008
- Primary completion
- Nov 30, 2015
- Completion
- Nov 30, 2016
- Last update posted
- Feb 19, 2020
2008 – 2016
United States locations
- U.S. sites
- 124
- U.S. states
- 19
- U.S. cities
- 93
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arkansas Cancer Research Center at University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Kaiser Permanente - Deer Valley | Antioch | California | 94531 | — |
| Alta Bates Summit Comprehensive Cancer Center | Berkeley | California | 94704 | — |
| Peninsula Medical Center | Burlingame | California | 94010 | — |
| Kaiser Permanente - Fremont | Fremont | California | 94538 | — |
| Kaiser Permanente Medical Center - Hayward | Hayward | California | 94545 | — |
| USC/Norris Comprehensive Cancer Center and Hospital | Los Angeles | California | 90089-9181 | — |
| Contra Costa Regional Medical Center | Martinez | California | 94553-3156 | — |
| Tibotec Therapeutics - Division of Ortho Biotech Products, LP | Marysville | California | 95901 | — |
| El Camino Hospital Cancer Center | Mountain View | California | 94040 | — |
| Sutter Health - Western Division Cancer Research Group | Novato | California | 94945 | — |
| Highland General Hospital | Oakland | California | 94602 | — |
| Alta Bates Summit Medical Center - Summit Campus | Oakland | California | 94609 | — |
| CCOP - Bay Area Tumor Institute | Oakland | California | 94609 | — |
| Kaiser Permanente Medical Center - Oakland | Oakland | California | 94611 | — |
| Epic Care - Oakland | Oakland | California | 94612 | — |
| Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center | Orange | California | 92868 | — |
| Kaiser Permanente Medical Center - Redwood City | Redwood City | California | 94063 | — |
| Kaiser Permanente Medical Center - Richmond | Richmond | California | 94801 | — |
| Kaiser Permanente Medical Center - Roseville | Roseville | California | 95661 | — |
| University of California Davis Cancer Center | Sacramento | California | 95817 | — |
| South Sacramento Kaiser-Permanente Medical Center | Sacramento | California | 95823 | — |
| Kaiser Permanente Medical Center - Sacramento | Sacramento | California | 95825 | — |
| Kaiser Permanente Medical Center - San Francisco Geary Campus | San Francisco | California | 94115 | — |
| California Pacific Medical Center - California Campus | San Francisco | California | 94118 | — |
| Kaiser Permanente Medical Center - Santa Teresa | San Jose | California | 95119 | — |
| Doctors Medical Center - San Pablo Campus | San Pablo | California | 94806 | — |
| Kaiser Foundation Hospital - San Rafael | San Rafael | California | 94903 | — |
| Kaiser Permanente Medical Center - Santa Clara Kiely Campus | Santa Clara | California | 95051 | — |
| Kaiser Permanente Medical Center - Santa Rosa | Santa Rosa | California | 95403 | — |
| Kaiser Permanente Medical Center - South San Francisco | South San Francisco | California | 94080 | — |
| Kaiser Permanente Medical Facility - Stockton | Stockton | California | 95210 | — |
| Tahoe Forest Cancer Center | Truckee | California | 96161 | — |
| Kaiser Permanente Medical Center - Vacaville | Vacaville | California | 95688 | — |
| Kaiser Permanente Medical Center - Vallejo | Vallejo | California | 94589 | — |
| Sutter Solano Medical Center | Vallejo | California | 94589 | — |
| Kaiser Permanente Medical Center - Walnut Creek | Walnut Creek | California | 94596 | — |
| Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center | Hartford | Connecticut | 06105 | — |
| Pearlman Comprehensive Cancer Center at South Georgia Medical Center | Valdosta | Georgia | 31602 | — |
| Kaiser Permanente - Moanalua Medical Center and Clinic | Honolulu | Hawaii | 96819 | — |
| Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center | Boise | Idaho | 83706 | — |
| Mountain States Tumor Institute at St. Luke's Regional Medical Center | Boise | Idaho | 83712 | — |
| Saint Luke's Mountain States Tumor Institute - Fruitland | Fruitland | Idaho | 83619 | — |
| Mountain States Tumor Institute - Meridian | Meridian | Idaho | 83642 | — |
| Saint Luke's Mountain States Tumor Institute | Nampa | Idaho | 83686 | — |
| Mountain States Tumor Institute at St. Luke's | Twin Falls | Idaho | 83301 | — |
| Decatur Memorial Hospital Cancer Care Institute | Decatur | Illinois | 62526 | — |
| Regional Cancer Center at Memorial Medical Center | Springfield | Illinois | 62781-0001 | — |
| St. Rose Ambulatory and Surgery Center | Great Bend | Kansas | 67530 | — |
| Hays Medical Center | Hays | Kansas | 67601 | — |
| Hutchinson Hospital Corporation | Hutchinson | Kansas | 67502 | — |
| Kansas City Cancer Centers - West | Kansas City | Kansas | 66112 | — |
| Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center | Kansas City | Kansas | 66160-7357 | — |
| Kansas City Cancer Centers - Southwest | Overland Park | Kansas | 66210 | — |
| Mount Carmel Regional Cancer Center | Pittsburg | Kansas | 66762 | — |
| Tammy Walker Cancer Center at Salina Regional Health Center | Salina | Kansas | 67401 | — |
| Kansas City Cancer Center - Shawnee Mission | Shawnee Mission | Kansas | 66204 | — |
| St. Francis Comprehensive Cancer Center | Topeka | Kansas | 66606 | — |
| Veterans Affairs Medical Center - Topeka (O'Neil) | Topeka | Kansas | 66622 | — |
| Cancer Center of Kansas, PA - Winfield | Winfield | Kansas | 67156 | — |
| Lahey Clinic Medical Center - Burlington | Burlington | Massachusetts | 01805 | — |
| Saint Joseph Mercy Cancer Center | Ann Arbor | Michigan | 48106-0995 | — |
| CCOP - Michigan Cancer Research Consortium | Ann Arbor | Michigan | 48106 | — |
| Oakwood Cancer Center at Oakwood Hospital and Medical Center | Dearborn | Michigan | 48123-2500 | — |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201-1379 | — |
| Genesys Hurley Cancer Institute | Flint | Michigan | 48503 | — |
| Hurley Medical Center | Flint | Michigan | 48503 | — |
| Van Elslander Cancer Center at St. John Hospital and Medical Center | Grosse Pointe Woods | Michigan | 48236 | — |
| Foote Memorial Hospital | Jackson | Michigan | 49201 | — |
| Sparrow Regional Cancer Center | Lansing | Michigan | 48912-1811 | — |
| St. Mary Mercy Hospital | Livonia | Michigan | 48154 | — |
| St. Joseph Mercy Oakland | Pontiac | Michigan | 48341-2985 | — |
| Mercy Regional Cancer Center at Mercy Hospital | Port Huron | Michigan | 48060 | — |
| Seton Cancer Institute at Saint Mary's - Saginaw | Saginaw | Michigan | 48601 | — |
| St. John Macomb Hospital | Warren | Michigan | 48093 | — |
| Regional Cancer Center at Singing River Hospital | Pascagoula | Mississippi | 39581 | — |
| Truman Medical Center - Hospital Hill | Kansas City | Missouri | 64108 | — |
| Veterans Affairs Medical Center - Kansas City | Kansas City | Missouri | 64128 | — |
| Kansas City Cancer Centers - South | Kansas City | Missouri | 64131 | — |
| Kansas City Cancer Centers - North | Kansas City | Missouri | 64154 | — |
| Kansas City Cancer Centers - East | Lee's Summit | Missouri | 64064 | — |
| CCOP - Cancer Research for the Ozarks | Springfield | Missouri | 65802 | — |
| St. John's Regional Health Center | Springfield | Missouri | 65804 | — |
| Hulston Cancer Center at Cox Medical Center South | Springfield | Missouri | 65807 | — |
| CCOP - Montana Cancer Consortium | Billings | Montana | 59101 | — |
| St. Vincent Healthcare Cancer Care Services | Billings | Montana | 59101 | — |
| Hematology-Oncology Centers of the Northern Rockies - Billings | Billings | Montana | 59102 | — |
| Billings Clinic - Downtown | Billings | Montana | 59107-7000 | — |
| Bozeman Deaconess Cancer Center | Bozeman | Montana | 59715 | — |
| Great Falls Clinic - Main Facility | Great Falls | Montana | 59405 | — |
| Sletten Cancer Institute at Benefis Healthcare | Great Falls | Montana | 59405 | — |
| St. Peter's Hospital | Helena | Montana | 59601 | — |
| Glacier Oncology, PLLC | Kalispell | Montana | 59901 | — |
| Kalispell Regional Medical Center | Kalispell | Montana | 59901 | — |
| Montana Cancer Specialists at Montana Cancer Center | Missoula | Montana | 59807-7877 | — |
| Montana Cancer Center at St. Patrick Hospital and Health Sciences Center | Missoula | Montana | 59807 | — |
| Randolph Hospital | Asheboro | North Carolina | 27203-5400 | — |
| Presbyterian Cancer Center at Presbyterian Hospital | Charlotte | North Carolina | 28233-3549 | — |
| Wayne Memorial Hospital, Incorporated | Goldsboro | North Carolina | 27534 | — |
| Moses Cone Regional Cancer Center at Wesley Long Community Hospital | Greensboro | North Carolina | 27403-1198 | — |
| Harrington Cancer Center | Amarillo | Texas | 79106 | — |
| Huntsman Cancer Institute at University of Utah | Salt Lake City | Utah | 84112 | — |
| Danville Regional Medical Center | Danville | Virginia | 24541 | — |
| Ravenel Oncology Center at Memorial Hospital of Martinsville and Henry County | Martinsville | Virginia | 24115 | — |
| Island Hospital Cancer Care Center at Island Hospital | Anacortes | Washington | 98221 | — |
| St. Joseph Cancer Center | Bellingham | Washington | 98225 | — |
| Olympic Hematology and Oncology | Bremerton | Washington | 98310 | — |
| Highline Medical Center Cancer Center | Burien | Washington | 98166 | — |
| Swedish Medical Center - Issaquah Campus | Issaquah | Washington | 98029 | — |
| Columbia Basin Hematology | Kennewick | Washington | 99336 | — |
| Skagit Valley Hospital Cancer Care Center | Mount Vernon | Washington | 98274 | — |
| Harrison Poulsbo Hematology and Onocology | Poulsbo | Washington | 98370 | — |
| Harborview Medical Center | Seattle | Washington | 98104 | — |
| Minor and James Medical, PLLC | Seattle | Washington | 98104 | — |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109 | — |
| Group Health Central Hospital | Seattle | Washington | 98112 | — |
| Swedish Cancer Institute at Swedish Medical Center - First Hill Campus | Seattle | Washington | 98122-4307 | — |
| Polyclinic First Hill | Seattle | Washington | 98122 | — |
| University Cancer Center at University of Washington Medical Center | Seattle | Washington | 98195 | — |
| North Puget Oncology at United General Hospital | Sedro-Woolley | Washington | 98284 | — |
| Cancer Care Northwest - Spokane South | Spokane | Washington | 99202 | — |
| Evergreen Hematology and Oncology, PS | Spokane | Washington | 99218 | — |
| Wenatchee Valley Medical Center | Wenatchee | Washington | 98801-2028 | — |
| Rocky Mountain Oncology | Casper | Wyoming | 82609 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00661193, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 19, 2020 · Synced Sep 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00661193 live on ClinicalTrials.gov.