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Completed Phase 2 Interventional Results available

Mitoxantrone ± Cetuximab 2nd Line Androgen Independent Prostate Cancer (AIPC)

ClinicalTrials.gov ID: NCT00661492

Public ClinicalTrials.gov record NCT00661492. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 5:05 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized Phase II Study of Mitoxantrone vs. Mitoxantrone With Cetuximab in Metastatic Androgen Independent Prostate Cancer (AIPC) Previously Treated With Docetaxel-based Chemotherapy

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

To determine the time to progression produced by the combination of Novantrone (mitoxantrone) and Erbitux (cetuximab) versus Novantrone alone in metastatic AIPC patients previously treated with docetaxel-based chemotherapy. TTP is defined as time from the start of treatment date to the date the patient is first recorded as having disease progression, even in patients who discontinue study treatment early due to toxicity.

Study identification

NCT ID
NCT00661492
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
US Oncology Research
Industry
Enrollment
115 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
Male
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 30, 2008
Primary completion
Feb 28, 2011
Completion
May 31, 2011
Last update posted
Dec 8, 2016

2008 – 2011

United States locations

U.S. sites
55
U.S. states
18
U.S. cities
52
Facility City State ZIP Site status
Hematology Oncology Associates Phoenix Arizona 85012
Northern AZ Hematology & Oncology Assoc Sedona Arizona 86336
Rocky Mountain Cancer Center-Midtown Denver Colorado 80218
Melbourne Internal Medicine Associates Melbourne Florida 32901
Florida Cancer Institute - New Hope New Port Richey Florida 34655
Ocala Oncology Center Ocala Florida 34474
Cancer Centers of Florida, P.A. Ocoee Florida 34761
Cancer Care & Hematology Specialists of Chicagoland Niles Illinois 60714
Central Indiana Cancer Centers Indianapolis Indiana 46277
Hope Center Terre Haute Indiana 47802
Minnesota Oncology Hematology, P.A. Minneapolis Minnesota 55404
Missouri Cancer Associates Columbia Missouri 65201
St. Joseph Oncology, Inc. Saint Joseph Missouri 64507
Comprehensive Cancer Centers of Nevada Las Vegas Nevada 89169
NH Oncology-Hematology PA Hooksett New Hampshire 03106
Hematology-Oncology Associates of NNJ, P Morristown New Jersey 07960
Albany Medical Cancer Center Albany New York 12208
Interlakes Oncology Hematology, PC Rochester New York 14623
Cancer Centers of North Carolina Raleigh North Carolina 27607
Greater Dayton Cancer Center Kettering Ohio 45409
Willamette Valley Cancer Center Eugene Oregon 97401
Oregon Health & Science University Portland Oregon 97239
Cancer Centers of the Carolinas Greenville South Carolina 29605
Texas Oncology, P.A. -Amarillo Amarillo Texas 79106
Texas Oncology, P.A. Arlington Texas 76012
Texas Oncology - Central Austin Cancer Center Austin Texas 78731
Mamie McFaddin Ward Cancer Center Beaumont Texas 77702
Texas Cancer Center at Medical City Dallas Texas 75230
Texas Oncology, P.A. Dallas Texas 75231
Methodist Charlton Cancer Ctr. Dallas Texas 75237
Texas Oncology, P.A. Dallas Texas 75246
Texas Cancer Center Denton Texas 76210
El Paso Cancer Treatment Ctr El Paso Texas 79915
Texas Oncology, P.A. Fort Worth Texas 76104
Texas Oncology, P.A Garland Texas 75042
Longview Cancer Center Longview Texas 75601
South Texas Cancer Center - McAllen McAllen Texas 78503
Texas Cancer Center of Mesquite Mesquite Texas 75150
Allison Cancer Center Midland Texas 79701
Texas Oncology - Odessa Odessa Texas 79761
Paris Regional Cancer Center Paris Texas 75460
Texas Cancer Center - Sherman Sherman Texas 75090
Texas Oncology Cancer Center-Sugar Land Sugar Land Texas 77479
Tyler Cancer Center Tyler Texas 75702
Texas Oncology, P.A. Webster Texas 77598
Fairfax Northern VA Hem-Onc PC Fairfax Virginia 22031
Virginia Oncology Associates Norfolk Virginia 23502
Onc and Hem Associates of SW VA, Inc. Salem Virginia 24153
Highline Medical Oncology Burien Washington 98166
Puget Sound Cancer Center-Edmonds Edmonds Washington 98026
Columbia Basin Hematology and Oncology Kennewick Washington 99336
Puget Sound Cancer Center-Seattle Seattle Washington 98133
Cancer Care Northwest-South Spokane Washington 99202
Northwest Cancer Specialists-Vancouver Vancouver Washington 98684
Yakima Valley Mem Hosp/North Star Lodge Yakima Washington 98902

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00661492, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 8, 2016 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00661492 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →