To Assess the Effect of Naproxcinod Versus Naproxen and Ibuprofen on Arterial Blood Pressure in Osteoarthritis Patients With Controlled Essential Hypertension
Public ClinicalTrials.gov record NCT00662896. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 16-week, Phase 1, Multicenter, Double-Blind, Randomized, Naproxen and Ibuprofen-controlled, Parallel-Group Pharmacological Study, to Assess the Effect of Naproxcinod (375mg and750mg, Bid) Compared to Doses of Naproxen (250mg and 500mg, Bid) and to Ibuprofen (600mg, Tid) on Arterial Blood Pressure as Measured by Ambulatory Blood Pressure Monitoring in Osteoarthritis Patients With Controlled Essential Hypertension.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To assess the effect of naproxcinod vs. naproxen and ibuprofen on arterial blood pressure in patients with osteoarthritis and controlled essential hypertension
Study identification
- NCT ID
- NCT00662896
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 300 participants
Conditions and interventions
Conditions
Interventions
- naproxcinod 375 mg bid Drug
- naproxcinod 750 mg bid Drug
- naproxen 250 mg bid Drug
- naproxen 500 mg bid Drug
- ibuprofen 600 mg tid Drug
Drug
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 2008 (Type not available)
- Primary completion
- Sep 2008 (Actual)
- Completion
- Dec 2008 (Actual)
- Last update posted
- Jun 17, 2011
2008
United States locations
- U.S. sites
- 57
- U.S. states
- 28
- U.S. cities
- 57
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Birmingham | Alabama | — | — |
| Not listed | Huntsville | Alabama | — | — |
| Not listed | Sierra Vista | Arizona | — | — |
| Not listed | Carmichael | California | — | — |
| Not listed | Fair Oaks | California | — | — |
| Not listed | Long Beach | California | — | — |
| Not listed | Pico Rivera | California | — | — |
| Not listed | Upland | California | — | — |
| Not listed | Denver | Colorado | — | — |
| Not listed | Farmington | Connecticut | — | — |
| Not listed | Milford | Connecticut | — | — |
| Not listed | Washington D.C. | District of Columbia | — | — |
| Not listed | Clearwater | Florida | — | — |
| Not listed | DeLand | Florida | — | — |
| Not listed | Fort Myers | Florida | — | — |
| Not listed | Gainesville | Florida | — | — |
| Not listed | Jupiter | Florida | — | — |
| Not listed | Kissimmee | Florida | — | — |
| Not listed | Miami | Florida | — | — |
| Not listed | Ormond Beach | Florida | — | — |
| Not listed | Pembroke Pines | Florida | — | — |
| Not listed | West Palm Beach | Florida | — | — |
| Not listed | Atlanta | Georgia | — | — |
| Not listed | Decatur | Georgia | — | — |
| Not listed | Marietta | Georgia | — | — |
| Not listed | Arlington Heights | Illinois | — | — |
| Not listed | Peoria | Illinois | — | — |
| Not listed | Elizabethtown | Kentucky | — | — |
| Not listed | Erlanger | Kentucky | — | — |
| Not listed | Metairie | Louisiana | — | — |
| Not listed | Shreveport | Louisiana | — | — |
| Not listed | Auburn | Maine | — | — |
| Not listed | Baltimore | Maryland | — | — |
| Not listed | Towson | Maryland | — | — |
| Not listed | Florissant | Missouri | — | — |
| Not listed | Missoula | Montana | — | — |
| Not listed | Grand Island | Nebraska | — | — |
| Not listed | Henderson | Nevada | — | — |
| Not listed | Albuquerque | New Mexico | — | — |
| Not listed | Rochester | New York | — | — |
| Not listed | Charlotte | North Carolina | — | — |
| Not listed | Concord | North Carolina | — | — |
| Not listed | Hickory | North Carolina | — | — |
| Not listed | Lenoir | North Carolina | — | — |
| Not listed | Cincinnati | Ohio | — | — |
| Not listed | Oklahoma City | Oklahoma | — | — |
| Not listed | Havertown | Pennsylvania | — | — |
| Not listed | Tipton | Pennsylvania | — | — |
| Not listed | Charleston | South Carolina | — | — |
| Not listed | Kingsport | Tennessee | — | — |
| Not listed | New Tazewell | Tennessee | — | — |
| Not listed | Dallas | Texas | — | — |
| Not listed | Irving | Texas | — | — |
| Not listed | Longview | Texas | — | — |
| Not listed | San Antonio | Texas | — | — |
| Not listed | Salt Lake City | Utah | — | — |
| Not listed | Madison | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00662896, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 17, 2011 · Synced Oct 29, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00662896 live on ClinicalTrials.gov.