Efficacy and Safety Study of R935788 Tablets to Treat Rheumatoid Arthritis
Public ClinicalTrials.gov record NCT00665925. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of Two Doses of R935788 in Rheumatoid Arthritis Patients Failing to Respond to Methotrexate
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether the Spleen Tyrosine Kinase (Syk) inhibitor, R935788 (R788), at a dose of 100 mg, orally, twice-a-day, and/or a dose of of 150 mg, orally, once-a-day is effective in the treatment of Rheumatoid Arthrits in patients who have had an inadequate clinical response to methotrexate.
Study identification
- NCT ID
- NCT00665925
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 457 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 30, 2008
- Primary completion
- May 31, 2009
- Completion
- May 31, 2009
- Last update posted
- Sep 15, 2016
2008 – 2009
United States locations
- U.S. sites
- 24
- U.S. states
- 16
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Divison of Rheumatology Allergy and Immunology | La Jolla | California | 92037 | — |
| Desert Medical Advances | Palm Desert | California | 92260 | — |
| Arthritis & Osteoporosis Center, PC | Hamden | Connecticut | 06518 | — |
| Cynthia Morgan | Washington D.C. | District of Columbia | 20003 | — |
| Florida Medical Research Institute | Gainsville | Florida | 32607 | — |
| Paddock Park Clinical Research | Ocala | Florida | 34474 | — |
| Jeffrey Poiley, MD | Orlando | Florida | 32804 | — |
| Lovelace Scientific Resources | Sarasota | Florida | 34233 | — |
| Rheumatology Associates, SC | Chicago | Illinois | 60612 | — |
| Memorial Medical Group Clinical Research Inst | South Bend | Indiana | 46601 | — |
| Center for Arthritis & Osteoporosis | Elizabethtown | Kentucky | 42701 | — |
| The Osteoporosis & Clinical Trials Center | Hagerstown | Maryland | 21740 | — |
| Fiechtner Research, Inc. | Lansing | Michigan | 48910 | — |
| Westroads Medical Group | Omaha | Nebraska | 68114 | — |
| North Carolina Arthritis & Allergy Care Center | Raleigh | North Carolina | 27609 | — |
| Wake Forest University | Winston-Salem | North Carolina | 27157 | — |
| Health Research of Oklahoma | Oklahoma City | Oklahoma | 73103 | — |
| Rheumatology Associates | Erie | Pennsylvania | 16508 | — |
| Clinical Research Center of Reading, LLP | West Reading | Pennsylvania | 19611 | — |
| Rheumatic Disease Associates | Willow Grove | Pennsylvania | 19090 | — |
| Rheumatology Associates | Charleston | South Carolina | 29407 | — |
| Austin Rheumatology & Research | Austin | Texas | 78705 | — |
| Arthritis Center of South Texas | San Antonio | Texas | 78232 | — |
| Arthritis Northwest, PLLC | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 41 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00665925, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 15, 2016 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00665925 live on ClinicalTrials.gov.