Study Evaluating The Efficacy And Safety Of Bapineuzumab In Alzheimer Disease Patients
Public ClinicalTrials.gov record NCT00667810. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Efficacy And Safety Trial Of Bapineuzumab (Aab-001, Eln115727) In Subjects With Mild to Moderate Alzheimer Disease Who Are Apolipoprotein E 4 Non-carriers
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a study to evaluate the efficacy and safety of multiple doses of bapineuzumab in patients with mild to moderate Alzheimer Disease. Patients will receive either bapineuzumab or placebo. Each patient's participation will last approximately 1.5 years.
Study identification
- NCT ID
- NCT00667810
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 901 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years to 89 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2008
- Primary completion
- Sep 30, 2012
- Completion
- Jul 31, 2013
- Last update posted
- Jan 7, 2016
2008 – 2013
United States locations
- U.S. sites
- 164
- U.S. states
- 33
- U.S. cities
- 101
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama-Birmingham | Birmingham | Alabama | 35294 | — |
| Dedicated Clinical Research | Goodyear | Arizona | 85395 | — |
| Banner Alzheimer's Institute | Phoenix | Arizona | 85006 | — |
| Jeffrey S. Gitt, DO, PC | Phoenix | Arizona | 85032 | — |
| The Compounding Center (IP Mixing Only) | Phoenix | Arizona | 85032 | — |
| Hope Research Institute | Phoenix | Arizona | 85050 | — |
| Clinical Trials, Inc. | Little Rock | Arkansas | 72205 | — |
| ATP Clinical Research, Incorporated | Costa Mesa | California | 92626 | — |
| Pharmacology Research Institute | Encino | California | 91316 | — |
| Margolin Brain Institute | Fresno | California | 93720 | — |
| Infusion Care Pharmacey | Laguna Hills | California | 92653 | — |
| Senior Clinical Trials, Incorporated | Laguna Hills | California | 92653 | — |
| Faculty Physicians and Surgeons of Loma Linda University School of Medicine | Loma Linda | California | 92354 | — |
| Loma Linda University Medical Center | Loma Linda | California | 92354 | — |
| Collaborative Neuroscience Network, Inc. | Long Beach | California | 90806 | — |
| Pharmacology Research Institute | Los Alamitos | California | 90720 | — |
| Pharmacology Research Institute | Newport Beach | California | 92660 | — |
| Coordinated Clinical Research | San Diego | California | 92103 | — |
| LabCorp | San Diego | California | 92103 | — |
| Sharp and Children's MRI Center, LLC | San Diego | California | 92123 | — |
| Sharp Infusion Therapy Center | San Diego | California | 92123 | — |
| Sharp Memorial Hospital | San Diego | California | 92123 | — |
| Sharp Mesa Vista Hospital | San Diego | California | 92123 | — |
| San Francisco Clinical Research Center | San Francisco | California | 94109 | — |
| Alpine Clinical Research Center, Inc. | Boulder | Colorado | 80304 | — |
| Associated Neurologists, PC | Boulder | Colorado | 80304 | — |
| The Mile High Research Center | Denver | Colorado | 80218 | — |
| Associated Neurologists, PC | Danbury | Connecticut | 06810 | — |
| Associated Neurologists of Southern Connecticut, P.C. | Fairfield | Connecticut | 06824 | — |
| Bendheim Cancer Center | Greenwich | Connecticut | 06830 | — |
| Center for Healthy Aging | Greenwich | Connecticut | 06830 | — |
| Institute for Neurodegenerative Disorders | New Haven | Connecticut | 06510 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06510 | — |
| Yale-New Haven Hospital | New Haven | Connecticut | 06510 | — |
| Yale-New Haven Hospital | New Haven | Connecticut | 06511 | — |
| Norman S. Werdiger, MD | New Haven | Connecticut | 06519 | — |
| Institutional Review Board / Ethics Committee | New Haven | Connecticut | 06520 | — |
| Yale PET Center | New Haven | Connecticut | 06520 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06520 | — |
| Research Center for Clinical Studies, Inc. | Norwalk | Connecticut | 06851 | — |
| Chase Medical Research, LLC | Waterbury | Connecticut | 06708 | — |
| JEM Research Institute LLC | Atlantis | Florida | 33462 | — |
| Medical Specialists of the Palm Beaches | Atlantis | Florida | 33462 | — |
| Bradenton Research Center, Incorporated | Bradenton | Florida | 34205 | — |
| North Broward Medical Center | Deerfield Beach | Florida | 33064 | — |
| Brain Matters Research | Delray Beach | Florida | 33445 | — |
| Neurologic Consultants, P.A. | Fort Lauderdale | Florida | 33308 | — |
| MD Clinical | Hallandale | Florida | 33009 | — |
| Renstar Medical Research | Ocala | Florida | 34471 | — |
| Advanced Imaging | Ocala | Florida | 34481 | — |
| Compass Research, LLC | Orlando | Florida | 32806 | — |
| Palm Beach Neurological Center | Palm Beach Gardens | Florida | 33410 | — |
| Neurostudies Inc | Port Charlotte | Florida | 33952 | — |
| Roskamp Institute | Sarasota | Florida | 34243 | — |
| South Bay Internal Medicine | Sun City | Florida | 33573 | — |
| Stedman Clinical Trials, LLC | Tampa | Florida | 33613 | — |
| Premiere Research Institute | West Palm Beach | Florida | 33407 | — |
| NeuroTrials Research, Incorporated | Atlanta | Georgia | 30342 | — |
| Columbus Diagnostic Center (MRI) | Columbus | Georgia | 31901 | — |
| Medical Research and Health Education Foundation, Incorporated | Columbus | Georgia | 31909 | — |
| Dekalb Neurology Associates, LLC/NeuroStudies.net, LLC | Decatur | Georgia | 30033 | — |
| NeuroStudies.net | Decatur | Georgia | 30033 | — |
| Neurostudies.net | Lawerenceville | Georgia | 30045 | — |
| Neurostudies.net | Lawrenceville | Georgia | 30046 | — |
| Alexian Brothers Medical Center | Elk Grove Village | Illinois | 60007 | — |
| Alexian Brothers Neurosciences Institute | Elk Grove Village | Illinois | 60007 | — |
| Methodist Center for Senior Health | Peoria | Illinois | 61602 | — |
| Methodist Medical Center Research Department | Peoria | Illinois | 61602 | — |
| Methodist Diagnostic Center | Peoria | Illinois | 61606 | — |
| Methodist Medical Center of Illinois | Peoria | Illinois | 61636 | — |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62702 | — |
| Memorial Medical Center | Springfield | Illinois | 62781 | — |
| Elkhart Clinic, LLC | Elkhart | Indiana | 46514 | — |
| Psychology Associates | Mishawaka | Indiana | 46545 | — |
| KU - Wichita | Wichita | Kansas | 67207 | — |
| Drug Shipment/ Storage | Wichitia | Kansas | 67205 | — |
| Four Rivers Clinical Research, Incorporated | Paducah | Kentucky | 42003 | — |
| Radio Pharmacy | Paducah | Kentucky | 42003 | — |
| Lake Charles Clinical Trials | Lake Charles | Louisiana | 70629 | — |
| Louisiana Research Associates Inc | New Orleans | Louisiana | 70114 | — |
| James Gary Booker, MD, APMC | Shreveport | Louisiana | 71104 | — |
| Foers Medical Arts Pharmacy | Bethesda | Maryland | 20814 | — |
| CBH Health, LLC | Rockville | Maryland | 20850 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 021147 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Bringham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Boston University | Boston | Massachusetts | 02118 | — |
| General Clinical Research Center | Boston | Massachusetts | 02118 | — |
| IDS Pharmacy | Boston | Massachusetts | 02118 | — |
| ActivMed Practices and Research, Inc. | Haverhill | Massachusetts | 01830 | — |
| Neurocare, Incorporated | Newton | Massachusetts | 02459 | — |
| Springfield Neurology Associates, LLC | Springfield | Massachusetts | 01104 | — |
| University of Michigan Health System | Ann Arbor | Michigan | 48109-5872 | — |
| University of Michigan Hospital | Ann Arbor | Michigan | 48109 | — |
| University of Michigan Health System | Ann Arbor | Michigan | 48110 | — |
| Michigan State University | East Lansing | Michigan | 48824 | — |
| Michigan State University | Lansing | Michigan | 48910 | — |
| Marty's Pharmacy | Flowood | Mississippi | 39232 | — |
| Precise Research Centers | Flowood | Mississippi | 39232 | — |
| Hattiesburg Clinic | Hattiesburg | Mississippi | 39401 | — |
| The Center for Pharmaceutical Research | Kansas City | Missouri | 64114 | — |
| Advanced Neurology Specialists | Great Falls | Montana | 59405 | — |
| Spectrum Home Solutions | Great Falls | Montana | 59405 | — |
| Comprehensive Clinical Research | Berlin | New Jersey | 08009 | — |
| Memory Enhancement Center of America, Inc. | Eatontown | New Jersey | 07724 | — |
| Alzheimer's Research Corporation | Paterson | New Jersey | 08759 | — |
| Memory Enhancement Center of New Jersey, Inc. | Toms River | New Jersey | 08755 | — |
| Northeast Radiology | Brewster | New York | 10509 | — |
| Neurological Care of Central New York | Liverpool | New York | 13088 | — |
| AD-CARE, University of Rochester Medical Center | Rochester | New York | 14620 | — |
| University of Rochester/Strong Memorial Hospital | Rochester | New York | 14642 | — |
| Clinical Study Center of Asheville, LLC | Asheville | North Carolina | 28803 | — |
| Alzheimer's Memory Center | Charlotte | North Carolina | 28211 | — |
| Clinical Trials of America, Incorporated | Hickory | North Carolina | 28601 | — |
| The Compounding Pharmacy | Hickory | North Carolina | 28602 | — |
| Carolina Neuropsychological Services, Inc. | Raleigh | North Carolina | 27607 | — |
| Healthsouth Blue Ridge Surgery Center | Raleigh | North Carolina | 27607 | — |
| Raleigh Neurology Associates, PA | Raleigh | North Carolina | 27607 | — |
| Wake Radiology Associates | Raleigh | North Carolina | 27607 | — |
| Ohio State University Imaging at Martha Morehouse | Columbus | Ohio | 43210 | — |
| The Ohio State University Hospitals Clinic | Columbus | Ohio | 43210 | — |
| The Ohio State University Medical Center | Columbus | Ohio | 43210 | — |
| The Ohio State University | Columbus | Ohio | 43210 | — |
| Neurology & Neuroscience Center of Ohio | Toledo | Ohio | 43623 | — |
| Professional Corporation of Psychiatry | Oklahoma City | Oklahoma | 73112 | — |
| Red River Medical Recearch Center, LLC | Oklahoma City | Oklahoma | 73112 | — |
| Flourish Integrative Pharmacy | Oklahoma City | Oklahoma | 73134 | — |
| Providence Brain Institute | Portland | Oregon | 97225 | — |
| Abington Memorial Hospital | Abington | Pennsylvania | 19001 | — |
| Abington Neurological Associates | Abington | Pennsylvania | 19001 | — |
| Clinical Trial Center, LLC | Jenkintown | Pennsylvania | 19046 | — |
| Hospital of the University of Pennslyvania | Philadelphia | Pennsylvania | 19104 | — |
| Hospital of the University of Pennsylvania (PET) | Philadelphia | Pennsylvania | 19104 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Investigational New Drug Services, IDS Pharmacy | Philadelphia | Pennsylvania | 19104 | — |
| Penn Memory Center | Philadelphia | Pennsylvania | 19104 | — |
| UPENN Clinical and Translational Research Center (CTRC) | Philadelphia | Pennsylvania | 19104 | — |
| Clinical Trials Research Services, LLC | Pittsburgh | Pennsylvania | 15206 | — |
| Abington Neurological Associates | Willow Grove | Pennsylvania | 19090 | — |
| Rhode Island Mood and Memory Research Institute | East Providence | Rhode Island | 02914 | — |
| Simpson's Pharmacy | Pawtucket | Rhode Island | 02861 | — |
| Butler Hospital | Providence | Rhode Island | 02906 | — |
| Medical University of South Carolina Hospitals and Clinics | Charleston | South Carolina | 29425 | — |
| Medical University of South Carolina Investigational Drug Service | Charleston | South Carolina | 29425 | — |
| Radiant Research, Incorporated | Greer | South Carolina | 29651 | — |
| Medical University of South Carolina | North Charleston | South Carolina | 29406 | — |
| Neurology Clinic, PC | Cordova | Tennessee | 38018 | — |
| Austin Infusion Centers | Austin | Texas | 78756 | — |
| Senior Adults Specialty Research | Austin | Texas | 78757 | — |
| Texas Neurology, P.A. | Dallas | Texas | 75214 | — |
| University of North Texas Health Science Center | Fort Worth | Texas | 76107 | — |
| Innovative Clinical Trials | San Antonio | Texas | 78229 | — |
| Integra Clinical Research, LLC | San Antonio | Texas | 78231 | — |
| Vista Infusions | San Antonio | Texas | 78231 | — |
| Inventive Infusion Solutions | San Antonio | Texas | 78258 | — |
| Grayline Clinical Drug Trials | Wichita Falls | Texas | 76309 | — |
| Southwestern Vermont Healthcare | Bennington | Vermont | 05201 | — |
| The Memory Clinic | Bennington | Vermont | 05201 | — |
| University of Virginia Neurology | Charlottesville | Virginia | 22903 | — |
| University of Virginia General Clinical Research Center | Charlottesville | Virginia | 22908 | — |
| University of Viriginia Investigational Pharmacy | Charlottesville | Virginia | 22908 | — |
| Pacific Medical Centers | Bothell | Washington | 98021 | — |
| Pacific Medical Centers | Seattle | Washington | 98144 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 182 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00667810, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 7, 2016 · Synced Sep 3, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00667810 live on ClinicalTrials.gov.