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Terminated Phase 3 Interventional Results available

Study Evaluating The Efficacy And Safety Of Bapineuzumab In Alzheimer Disease Patients

ClinicalTrials.gov ID: NCT00667810

Public ClinicalTrials.gov record NCT00667810. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 11:32 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Efficacy And Safety Trial Of Bapineuzumab (Aab-001, Eln115727) In Subjects With Mild to Moderate Alzheimer Disease Who Are Apolipoprotein E 4 Non-carriers

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a study to evaluate the efficacy and safety of multiple doses of bapineuzumab in patients with mild to moderate Alzheimer Disease. Patients will receive either bapineuzumab or placebo. Each patient's participation will last approximately 1.5 years.

Study identification

NCT ID
NCT00667810
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Pfizer
Industry
Enrollment
901 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
50 Years to 89 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 2008 (Type not available)
Primary completion
Oct 2012 (Actual)
Completion
Aug 2013 (Actual)
Last update posted
Jan 8, 2016

2008 – 2013

United States locations

U.S. sites
164
U.S. states
33
U.S. cities
101
Facility City State ZIP Site status
University of Alabama-Birmingham Birmingham Alabama 35294 —
Dedicated Clinical Research Goodyear Arizona 85395 —
Banner Alzheimer's Institute Phoenix Arizona 85006 —
Jeffrey S. Gitt, DO, PC Phoenix Arizona 85032 —
The Compounding Center (IP Mixing Only) Phoenix Arizona 85032 —
Hope Research Institute Phoenix Arizona 85050 —
Clinical Trials, Inc. Little Rock Arkansas 72205 —
ATP Clinical Research, Incorporated Costa Mesa California 92626 —
Pharmacology Research Institute Encino California 91316 —
Margolin Brain Institute Fresno California 93720 —
Infusion Care Pharmacey Laguna Hills California 92653 —
Senior Clinical Trials, Incorporated Laguna Hills California 92653 —
Faculty Physicians and Surgeons of Loma Linda University School of Medicine Loma Linda California 92354 —
Loma Linda University Medical Center Loma Linda California 92354 —
Collaborative Neuroscience Network, Inc. Long Beach California 90806 —
Pharmacology Research Institute Los Alamitos California 90720 —
Pharmacology Research Institute Newport Beach California 92660 —
Coordinated Clinical Research San Diego California 92103 —
LabCorp San Diego California 92103 —
Sharp and Children's MRI Center, LLC San Diego California 92123 —
Sharp Infusion Therapy Center San Diego California 92123 —
Sharp Memorial Hospital San Diego California 92123 —
Sharp Mesa Vista Hospital San Diego California 92123 —
San Francisco Clinical Research Center San Francisco California 94109 —
Alpine Clinical Research Center, Inc. Boulder Colorado 80304 —
Associated Neurologists, PC Boulder Colorado 80304 —
The Mile High Research Center Denver Colorado 80218 —
Associated Neurologists, PC Danbury Connecticut 06810 —
Associated Neurologists of Southern Connecticut, P.C. Fairfield Connecticut 06824 —
Bendheim Cancer Center Greenwich Connecticut 06830 —
Center for Healthy Aging Greenwich Connecticut 06830 —
Institute for Neurodegenerative Disorders New Haven Connecticut 06510 —
Yale University School of Medicine New Haven Connecticut 06510 —
Yale-New Haven Hospital New Haven Connecticut 06510 —
Yale-New Haven Hospital New Haven Connecticut 06511 —
Norman S. Werdiger, MD New Haven Connecticut 06519 —
Institutional Review Board / Ethics Committee New Haven Connecticut 06520 —
Yale PET Center New Haven Connecticut 06520 —
Yale University School of Medicine New Haven Connecticut 06520 —
Research Center for Clinical Studies, Inc. Norwalk Connecticut 06851 —
Chase Medical Research, LLC Waterbury Connecticut 06708 —
JEM Research Institute LLC Atlantis Florida 33462 —
Medical Specialists of the Palm Beaches Atlantis Florida 33462 —
Bradenton Research Center, Incorporated Bradenton Florida 34205 —
North Broward Medical Center Deerfield Beach Florida 33064 —
Brain Matters Research Delray Beach Florida 33445 —
Neurologic Consultants, P.A. Fort Lauderdale Florida 33308 —
MD Clinical Hallandale Florida 33009 —
Renstar Medical Research Ocala Florida 34471 —
Advanced Imaging Ocala Florida 34481 —
Compass Research, LLC Orlando Florida 32806 —
Palm Beach Neurological Center Palm Beach Gardens Florida 33410 —
Neurostudies Inc Port Charlotte Florida 33952 —
Roskamp Institute Sarasota Florida 34243 —
South Bay Internal Medicine Sun City Florida 33573 —
Stedman Clinical Trials, LLC Tampa Florida 33613 —
Premiere Research Institute West Palm Beach Florida 33407 —
NeuroTrials Research, Incorporated Atlanta Georgia 30342 —
Columbus Diagnostic Center (MRI) Columbus Georgia 31901 —
Medical Research and Health Education Foundation, Incorporated Columbus Georgia 31909 —
Dekalb Neurology Associates, LLC/NeuroStudies.net, LLC Decatur Georgia 30033 —
NeuroStudies.net Decatur Georgia 30033 —
Neurostudies.net Lawerenceville Georgia 30045 —
Neurostudies.net Lawrenceville Georgia 30046 —
Alexian Brothers Medical Center Elk Grove Village Illinois 60007 —
Alexian Brothers Neurosciences Institute Elk Grove Village Illinois 60007 —
Methodist Center for Senior Health Peoria Illinois 61602 —
Methodist Medical Center Research Department Peoria Illinois 61602 —
Methodist Diagnostic Center Peoria Illinois 61606 —
Methodist Medical Center of Illinois Peoria Illinois 61636 —
Southern Illinois University School of Medicine Springfield Illinois 62702 —
Memorial Medical Center Springfield Illinois 62781 —
Elkhart Clinic, LLC Elkhart Indiana 46514 —
Psychology Associates Mishawaka Indiana 46545 —
KU - Wichita Wichita Kansas 67207 —
Drug Shipment/ Storage Wichitia Kansas 67205 —
Four Rivers Clinical Research, Incorporated Paducah Kentucky 42003 —
Radio Pharmacy Paducah Kentucky 42003 —
Lake Charles Clinical Trials Lake Charles Louisiana 70629 —
Louisiana Research Associates Inc New Orleans Louisiana 70114 —
James Gary Booker, MD, APMC Shreveport Louisiana 71104 —
Foers Medical Arts Pharmacy Bethesda Maryland 20814 —
CBH Health, LLC Rockville Maryland 20850 —
Massachusetts General Hospital Boston Massachusetts 021147 —
Massachusetts General Hospital Boston Massachusetts 02114 —
Brigham and Women's Hospital Boston Massachusetts 02115 —
Bringham and Women's Hospital Boston Massachusetts 02115 —
Boston University Boston Massachusetts 02118 —
General Clinical Research Center Boston Massachusetts 02118 —
IDS Pharmacy Boston Massachusetts 02118 —
ActivMed Practices and Research, Inc. Haverhill Massachusetts 01830 —
Neurocare, Incorporated Newton Massachusetts 02459 —
Springfield Neurology Associates, LLC Springfield Massachusetts 01104 —
University of Michigan Health System Ann Arbor Michigan 48109-5872 —
University of Michigan Hospital Ann Arbor Michigan 48109 —
University of Michigan Health System Ann Arbor Michigan 48110 —
Michigan State University East Lansing Michigan 48824 —
Michigan State University Lansing Michigan 48910 —
Marty's Pharmacy Flowood Mississippi 39232 —
Precise Research Centers Flowood Mississippi 39232 —
Hattiesburg Clinic Hattiesburg Mississippi 39401 —
The Center for Pharmaceutical Research Kansas City Missouri 64114 —
Advanced Neurology Specialists Great Falls Montana 59405 —
Spectrum Home Solutions Great Falls Montana 59405 —
Comprehensive Clinical Research Berlin New Jersey 08009 —
Memory Enhancement Center of America, Inc. Eatontown New Jersey 07724 —
Alzheimer's Research Corporation Paterson New Jersey 08759 —
Memory Enhancement Center of New Jersey, Inc. Toms River New Jersey 08755 —
Northeast Radiology Brewster New York 10509 —
Neurological Care of Central New York Liverpool New York 13088 —
AD-CARE, University of Rochester Medical Center Rochester New York 14620 —
University of Rochester/Strong Memorial Hospital Rochester New York 14642 —
Clinical Study Center of Asheville, LLC Asheville North Carolina 28803 —
Alzheimer's Memory Center Charlotte North Carolina 28211 —
Clinical Trials of America, Incorporated Hickory North Carolina 28601 —
The Compounding Pharmacy Hickory North Carolina 28602 —
Carolina Neuropsychological Services, Inc. Raleigh North Carolina 27607 —
Healthsouth Blue Ridge Surgery Center Raleigh North Carolina 27607 —
Raleigh Neurology Associates, PA Raleigh North Carolina 27607 —
Wake Radiology Associates Raleigh North Carolina 27607 —
Ohio State University Imaging at Martha Morehouse Columbus Ohio 43210 —
The Ohio State University Hospitals Clinic Columbus Ohio 43210 —
The Ohio State University Medical Center Columbus Ohio 43210 —
The Ohio State University Columbus Ohio 43210 —
Neurology & Neuroscience Center of Ohio Toledo Ohio 43623 —
Professional Corporation of Psychiatry Oklahoma City Oklahoma 73112 —
Red River Medical Recearch Center, LLC Oklahoma City Oklahoma 73112 —
Flourish Integrative Pharmacy Oklahoma City Oklahoma 73134 —
Providence Brain Institute Portland Oregon 97225 —
Abington Memorial Hospital Abington Pennsylvania 19001 —
Abington Neurological Associates Abington Pennsylvania 19001 —
Clinical Trial Center, LLC Jenkintown Pennsylvania 19046 —
Hospital of the University of Pennslyvania Philadelphia Pennsylvania 19104 —
Hospital of the University of Pennsylvania (PET) Philadelphia Pennsylvania 19104 —
Hospital of the University of Pennsylvania Philadelphia Pennsylvania 19104 —
Investigational New Drug Services, IDS Pharmacy Philadelphia Pennsylvania 19104 —
Penn Memory Center Philadelphia Pennsylvania 19104 —
UPENN Clinical and Translational Research Center (CTRC) Philadelphia Pennsylvania 19104 —
Clinical Trials Research Services, LLC Pittsburgh Pennsylvania 15206 —
Abington Neurological Associates Willow Grove Pennsylvania 19090 —
Rhode Island Mood and Memory Research Institute East Providence Rhode Island 02914 —
Simpson's Pharmacy Pawtucket Rhode Island 02861 —
Butler Hospital Providence Rhode Island 02906 —
Medical University of South Carolina Hospitals and Clinics Charleston South Carolina 29425 —
Medical University of South Carolina Investigational Drug Service Charleston South Carolina 29425 —
Radiant Research, Incorporated Greer South Carolina 29651 —
Medical University of South Carolina North Charleston South Carolina 29406 —
Neurology Clinic, PC Cordova Tennessee 38018 —
Austin Infusion Centers Austin Texas 78756 —
Senior Adults Specialty Research Austin Texas 78757 —
Texas Neurology, P.A. Dallas Texas 75214 —
University of North Texas Health Science Center Fort Worth Texas 76107 —
Innovative Clinical Trials San Antonio Texas 78229 —
Integra Clinical Research, LLC San Antonio Texas 78231 —
Vista Infusions San Antonio Texas 78231 —
Inventive Infusion Solutions San Antonio Texas 78258 —
Grayline Clinical Drug Trials Wichita Falls Texas 76309 —
Southwestern Vermont Healthcare Bennington Vermont 05201 —
The Memory Clinic Bennington Vermont 05201 —
University of Virginia Neurology Charlottesville Virginia 22903 —
University of Virginia General Clinical Research Center Charlottesville Virginia 22908 —
University of Viriginia Investigational Pharmacy Charlottesville Virginia 22908 —
Pacific Medical Centers Bothell Washington 98021 —
Pacific Medical Centers Seattle Washington 98144 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 182 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00667810, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 8, 2016 · Synced Oct 19, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00667810 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →