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Completed Phase 2 Interventional Results available

Study to Examine Safety, Tolerability, and Effect on Body Weight of Metreleptin Administered in Conjunction With Pramlintide in Obese and Overweight Subjects

ClinicalTrials.gov ID: NCT00673387

Public ClinicalTrials.gov record NCT00673387. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 9:12 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Examine the Safety, Tolerability, and Effect on Body Weight of Metreleptin Administered in Conjunction With Pramlintide in Obese and Overweight Subjects.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

A randomized, double-blind, placebo-controlled, dose-ranging study to examine the safety, tolerability and effect on body weight of a range of doses of metreleptin and pramlintide, each administered by a separate subcutaneous (SC) injection in obese and overweight subjects.

Study identification

NCT ID
NCT00673387
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
AstraZeneca
Industry
Enrollment
636 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2008
Primary completion
Mar 31, 2009
Completion
Sep 30, 2009
Last update posted
Apr 14, 2015

2008 – 2009

United States locations

U.S. sites
36
U.S. states
24
U.S. cities
36
Facility City State ZIP Site status
Research Site Birmingham Alabama
Research Site Chandler Arizona
Research Site Santa Rosa California
Research Site Walnut Creek California
Research Site Denver Colorado
Research Site Jacksonville Florida
Research Site Miami Florida
Research Site Pembrook Pines Florida
Research Site Plantation Florida
Research Site Atlanta Georgia
Research Site Chicago Illinois
Research Site Springfield Illinois
Research Site Overland Park Kansas
Research Site Baton Rouge Louisiana
Research Site Auburn Maine
Research Site Boston Massachusetts
Research Site Edina Minnesota
Research Site St Louis Missouri
Research Site Butte Montana
Research Site New York New York
Research Site Statesville North Carolina
Research Site Cincinnati Ohio
Research Site Columbus Ohio
Research Site Eugene Oregon
Research Site Medford Oregon
Research Site Anderson South Carolina
Research Site Greer South Carolina
Research Site Mt. Pleasant South Carolina
Research Site Nashville Tennessee
Research Site Austin Texas
Research Site Dallas Texas
Research Site San Antonio Texas
Research Site Salt Lake City Utah
Research Site Norfolk Virginia
Research Site Belingham Washington
Research Site Olympia Washington

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00673387, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 14, 2015 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00673387 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →