Evaluating The Safety Of Donepezil Hydrochloride (Aricept) For Up To 1 Year In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome - Follow-Up To A 10-Week, Double-Blind, Placebo-Controlled Trial
Public ClinicalTrials.gov record NCT00675025. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-label Study to Evaluate the Safety of Donepezil Hydrochloride((Aricept®) for up to 1 Year in the Treatment of Cognitive Dysfunction Exhibited by Children With Down Syndrome-Follow-up to a 10-Week,Double-Blind,Placebo-Controlled Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the safety of donepezil hydrochloride (Aricept) in children with Down syndrome who have finished the preceding 10-week, double-blind study of donepezil hydrochloride. Medical tests for drug safety will be conducted at each clinic visit.
Study identification
- NCT ID
- NCT00675025
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 117 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 10 Years to 17 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 4, 2008 (Actual)
- Primary completion
- Nov 13, 2008 (Actual)
- Completion
- Dec 15, 2008 (Actual)
- Last update posted
- Mar 29, 2021
2008
United States locations
- U.S. sites
- 31
- U.S. states
- 18
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Phoenix Children's Hospital | Phoenix | Arizona | 85016 | — |
| Child Neurology Associates, PC | Little Rock | Arkansas | 72205 | — |
| Midwest Children's Health Research Institute | Los Angeles | California | 90048 | — |
| Children's Hospital and Research Center at Oakland | Oakland | California | 94609 | — |
| University of California, Irvine Medical Center | Orange | California | 92868 | — |
| UCSD Pediatric Pharmacology Research Unit | San Diego | California | 92123 | — |
| Rocky Mountain Pediatrics, P.C. | Lakewood | Colorado | 80214 | — |
| Neufeld Medical Group, Inc. | Fort Myers | Florida | 33912 | — |
| Miami Children's Hospital | Miami | Florida | 33155-3009 | — |
| Miami Children's Hospital - Medical Genetics and Neuro-Developmental Center | Miami | Florida | 33155 | — |
| Phoenix Children's Hospital | Miami | Florida | 33155 | — |
| Clinical Studies Centers, LLC | St. Petersburg | Florida | 33709 | — |
| Northwest Clinical Research Center | West Palm Beach | Florida | 33407 | — |
| Road Runner Research | Atlanta | Georgia | 30342 | — |
| Hurley Medical Center | Flint | Michigan | 48503 | — |
| Saint Mary's Health Care | Grand Rapids | Michigan | 49503 | — |
| Washington University School of Medicine | Grand Rapids | Michigan | 49503 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101-2595 | — |
| Northwest Clinical Research Center | St Louis | Missouri | 63110 | — |
| Meridien Research | Lincoln | Nebraska | 68504 | — |
| Clinical Research Center of New Jersey | Voorhees Township | New Jersey | 08043 | — |
| Division of Genetics and Developmental Behavior | Durham | North Carolina | 27710 | — |
| Metrohealth Medical Center | Cleveland | Ohio | 44109 | — |
| Valko and Associates | Toledo | Ohio | 43606 | — |
| Office of Lazlo Mate | Tulsa | Oklahoma | 74104 | — |
| Medical Univ of South Carolina | Charleston | South Carolina | 29425 | — |
| Vanderbilt Children's Hospital | Nashville | Tennessee | 37232-9225 | — |
| Down Syndrome Clinic of Houston | Houston | Texas | 77030 | — |
| Alamo City Clinical Research, LLC | San Antonio | Texas | 78258 | — |
| Community Research Foundation | San Antonio | Texas | 78258 | — |
| Neuropsychiatric Research Center of Southwest Florida | Bellevue | Washington | 98004 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00675025, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 29, 2021 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00675025 live on ClinicalTrials.gov.