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Terminated Phase 3 Interventional Results available

Study Evaluating the Safety and Efficacy of Bapineuzumab in Alzheimer Disease Patients

ClinicalTrials.gov ID: NCT00676143

Public ClinicalTrials.gov record NCT00676143. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 31, 2026, 7:25 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase Iii, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group, Efficacy And Safety Trial Of Bapineuzumab (Aab 001, Eln115727) In Subjects With Mild To Moderate Alzheimer Disease Who Are Apolipoprotein E 4 Carriers

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a study to evaluate the efficacy and safety of multiple doses of bapineuzumab in patients with mild to moderate Alzheimer Disease. Patients will receive either bapineuzumab or placebo. Each patient's participation will last approximately 1.5 years.

Study identification

NCT ID
NCT00676143
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Pfizer
Industry
Enrollment
1,100 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
50 Years to 88 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 2008 (Type not available)
Primary completion
Oct 2012 (Actual)
Completion
Nov 2012 (Actual)
Last update posted
Jun 10, 2016

2008 – 2012

United States locations

U.S. sites
111
U.S. states
26
U.S. cities
57
Facility City State ZIP Site status
Center for Psychiatric Medicine Birmingham Alabama 35294 —
Participant and Clinical Interactions Resources Birmingham Alabama 35294 —
UAB Clinical Research Pharmacy-Russell Clinic Birmingham Alabama 35294 —
University of Alabama-Birmingham Birmingham Alabama 35294 —
Dedicated Clinical Research Goodyear Arizona 85395 —
Banner Alzheimer's Institute Phoenix Arizona 85006 —
Jeffrey S. Gitt, DO, PC Phoenix Arizona 85032 —
The Compounding Center Phoenix Arizona 85032 —
HOPE Research Institute Phoenix Arizona 85050 —
Clinical Trials, Inc. Little Rock Arkansas 72205 —
AC Institute, Incorporated Carson California 90746 —
Collaborative Neuroscience Network, Inc Long Beach California 90806 —
San Francisco Clinical Research Center San Francisco California 94109 —
Alpine Clinical Research Center, Inc. Boulder Colorado 80304 —
Associated Neurologists, PC Boulder Colorado 80304 —
Mile HIgh Research Center Denver Colorado 80218 —
Associated Neurologists of Southern Connecticut, P.C. Fairfield Connecticut 06824 —
Bendheim Cancer Center Greenwich Connecticut 06830 —
Center for Healthy Aging Greenwich Connecticut 06830 —
Alzheimer's Disease Research Unit New Haven Connecticut 06510 —
Hospital Research Unit New Haven Connecticut 06510 —
Investigational Drug Service New Haven Connecticut 06511 —
Moshe Hasbani, MD New Haven Connecticut 06511 —
Norman S. Werdiger, MD New Haven Connecticut 06519 —
MR Research Center New Haven Connecticut 06520 —
Yale PET Center New Haven Connecticut 06520 —
Research Center for Clinical Studies, Inc. Norwalk Connecticut 06851 —
JEM Research Institute, LLC Atlantis Florida 33462 —
JEM Research Institute Atlantis Florida 33462 —
Medical Specialist of the Palm Beaches Atlantis Florida 33462 —
Brain Matters Research Delray Beach Florida 33445 —
Compass Research, LLC Orlando Florida 32806 —
Palm Beach Neurological Center Palm Beach Gardens Florida 33418 —
Neurostudies Inc Port Charlotte Florida 33952 —
Roskamp Institute Sarasota Florida 34243 —
University of South Florida Tampa Florida 33613 —
Dekalb Neurology Associates, LLC/NeuroStudies.net, LLC Decatur Georgia 30033 —
Neurostudies.net Decatur Georgia 30033 —
NeuroStudies.net Lawrenceville Georgia 30045 —
Alexian Brothers Medical Center Elk Grove Village Illinois 60007 —
Southern Illinois University School of Medicine Department Springfield Illinois 62702 —
Memorial Medical Center Springfield Illinois 62781 —
University of Kansas Medical Center Kansas City Kansas 66160 —
Lake Charles Clinical Trials Lake Charles Louisiana 70629 —
Massachusetts General Hospital Boston Massachusetts 02114 —
Massachusetts General Hosptial Boston Massachusetts 02114 —
Brigham & Womens Hospital Boston Massachusetts 02115 —
Brigham and Women's Hospital Boston Massachusetts 02115 —
Boston Univeristy ADCRP Boston Massachusetts 02118 —
General Clincial Research Center (Infusion Location) Boston Massachusetts 02118 —
IDS Pharmacy (Drug Receipt). Attn:Hyesson Hong Boston Massachusetts 02118 —
Neuroscience Research of the Berkshires Pittsfield Massachusetts 01201 —
Shields MRI Russells Mills Massachusetts 02747 —
Springfield Neurology Associates, LLC Springfield Massachusetts 01104 —
University of Michigan Hospital and Health System Ann Arbor Michigan 48105-2945 —
University of Michigan Health System Ann Arbor Michigan 48109-5872 —
University of Michigan Health System Ann Arbor Michigan 48109 —
University of Michigan Health System Ann Arbor Michigan 48110 —
Michigan State University East Lansing Michigan 48824 —
Hattiesburg Clinic Hattiesburg Mississippi 39401 —
The Center for Pharmaceutical Research P.C. Kansas City Missouri 64114 —
Memory Enhancement Center of America, Inc. Eatontown New Jersey 07724 —
Pharmcare USA Edison New Jersey 08837 —
Alzheimer's Research Corp./Merician Institute for Aging Paterson New Jersey 08759 —
Neurological Care of Central New York Liverpool New York 13088 —
Carolina Neuropsychological Services, Inc Raleigh North Carolina 27607 —
Healthsouth Blue Ridge Surgery Center Raleigh North Carolina 27607 —
Raleigh Neurology Associates Raleigh North Carolina 27607 —
Wake Radiology Associates Raleigh North Carolina 27607 —
Ohio State University Imaging@Martha Moorehouse Columbs Ohio 43210 —
The Ohio State University Columbs Ohio 43210 —
The Ohio State University Columbus Ohio 43210 —
Summit Research Network(Oregon) Inc. Portland Oregon 97210 —
Providence Brain Institute Portland Oregon 97225 —
Providence Cognitive Assessment Clinic Portland Oregon 97225 —
Providence St. Vincent Medical Center Portland Oregon 97225 —
Dr. Michael Gabe (Clinic) Silverton Oregon 97381 —
Abington Memorial Hosptial Abington Pennsylvania 19001 —
Abington Neurological Associates Abington Pennsylvania 19001 —
Abington Neurological Assoc Abington Pennsylvania 19001 —
Andorra MRI of Flourtown Flourtown Pennsylvania 19031 —
The Clinical Trial Center, LLC Jenkintown Pennsylvania 19046 —
Hospital of the University of Pennsylvania Philadelphia Pennsylvania 19104 —
Investigational New Drug Services Philadelphia Pennsylvania 19104 —
University of Pennsylvania-Penn Memory Center Philadelphia Pennsylvania 19104 —
UPENN Clinical and Transitional Research Center Philadelphia Pennsylvania 19104 —
Jefferson Hospital for Neuroscience Philadelphia Pennsylvania 19107 —
Thomas Jefferson University Hospital Philadelphia Pennsylvania 19107 —
Abington Neurological Associates Willow Grove Pennsylvania 19090 —
Rhode Island Mood and Memory Research Institute East Providence Rhode Island 02914 —
Simpson's Pharmacy Pawtucket Rhode Island 02861 —
Butler Hospital Providence Rhode Island 02906 —
Medical University of South Carolina Hospitals and Clinics Charleston South Carolina 29425 —
Medical University of South Carolina Charleston South Carolina 29425 —
MUSC Charleston South Carolina 29425 —
Medical University of South Carolina North Charleston South Carolina 29406 —
Texas Neurology, P.A. Dallas Texas 75214 —
Innovative Clinical Trials San Antonio Texas 78229 —
Integra Clinical Research San Antonio Texas 78229 —
Integra Clinical Research, LLC San Antonio Texas 78231 —
Integra Clinical Research San Antonio Texas 78231 —
Vista Infusions San Antonio Texas 78231 —
Inventive Infusion Solutions San Antonio Texas 78258 —
Inventive Infusions Solutions San Antonio Texas 78258 —
The Memory Clinic Bennington Vermont 05201 —
The Pharmacy Bennington Vermont 05201 —
Waisman Center (PET only) Madison Wisconsin 53705-2280 —
University of Wisconsin School of Medicine and Public Health Madison Wisconsin 53705 —
Wm S. Middleton Memorial Veterans Hospital Madison Wisconsin 53705 —
University of Wisconsin Hospitals and Clinics Madison Wisconsin 53792 —
University of Wisconsin School of Medicine and Public Health Madison Wisconsin 53792 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 177 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00676143, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 10, 2016 · Synced Oct 31, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00676143 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →