Study Evaluating the Safety and Efficacy of Bapineuzumab in Alzheimer Disease Patients
Public ClinicalTrials.gov record NCT00676143. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase Iii, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group, Efficacy And Safety Trial Of Bapineuzumab (Aab 001, Eln115727) In Subjects With Mild To Moderate Alzheimer Disease Who Are Apolipoprotein E 4 Carriers
Study identification
- NCT ID
- NCT00676143
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Pfizer
- Industry
- Enrollment
- 1,100 participants
Conditions and interventions
Conditions
Interventions
- bapineuzumab Drug
- placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 50 Years to 88 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 31, 2007
- Primary completion
- Sep 30, 2012
- Completion
- Oct 31, 2012
- Last update posted
- Jun 9, 2016
2008 – 2012
United States locations
- U.S. sites
- 111
- U.S. states
- 26
- U.S. cities
- 57
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Center for Psychiatric Medicine | Birmingham | Alabama | 35294 | — |
| Participant and Clinical Interactions Resources | Birmingham | Alabama | 35294 | — |
| UAB Clinical Research Pharmacy-Russell Clinic | Birmingham | Alabama | 35294 | — |
| University of Alabama-Birmingham | Birmingham | Alabama | 35294 | — |
| Dedicated Clinical Research | Goodyear | Arizona | 85395 | — |
| Banner Alzheimer's Institute | Phoenix | Arizona | 85006 | — |
| Jeffrey S. Gitt, DO, PC | Phoenix | Arizona | 85032 | — |
| The Compounding Center | Phoenix | Arizona | 85032 | — |
| HOPE Research Institute | Phoenix | Arizona | 85050 | — |
| Clinical Trials, Inc. | Little Rock | Arkansas | 72205 | — |
| AC Institute, Incorporated | Carson | California | 90746 | — |
| Collaborative Neuroscience Network, Inc | Long Beach | California | 90806 | — |
| San Francisco Clinical Research Center | San Francisco | California | 94109 | — |
| Alpine Clinical Research Center, Inc. | Boulder | Colorado | 80304 | — |
| Associated Neurologists, PC | Boulder | Colorado | 80304 | — |
| Mile HIgh Research Center | Denver | Colorado | 80218 | — |
| Associated Neurologists of Southern Connecticut, P.C. | Fairfield | Connecticut | 06824 | — |
| Bendheim Cancer Center | Greenwich | Connecticut | 06830 | — |
| Center for Healthy Aging | Greenwich | Connecticut | 06830 | — |
| Alzheimer's Disease Research Unit | New Haven | Connecticut | 06510 | — |
| Hospital Research Unit | New Haven | Connecticut | 06510 | — |
| Investigational Drug Service | New Haven | Connecticut | 06511 | — |
| Moshe Hasbani, MD | New Haven | Connecticut | 06511 | — |
| Norman S. Werdiger, MD | New Haven | Connecticut | 06519 | — |
| MR Research Center | New Haven | Connecticut | 06520 | — |
| Yale PET Center | New Haven | Connecticut | 06520 | — |
| Research Center for Clinical Studies, Inc. | Norwalk | Connecticut | 06851 | — |
| JEM Research Institute, LLC | Atlantis | Florida | 33462 | — |
| JEM Research Institute | Atlantis | Florida | 33462 | — |
| Medical Specialist of the Palm Beaches | Atlantis | Florida | 33462 | — |
| Brain Matters Research | Delray Beach | Florida | 33445 | — |
| Compass Research, LLC | Orlando | Florida | 32806 | — |
| Palm Beach Neurological Center | Palm Beach Gardens | Florida | 33418 | — |
| Neurostudies Inc | Port Charlotte | Florida | 33952 | — |
| Roskamp Institute | Sarasota | Florida | 34243 | — |
| University of South Florida | Tampa | Florida | 33613 | — |
| Dekalb Neurology Associates, LLC/NeuroStudies.net, LLC | Decatur | Georgia | 30033 | — |
| Neurostudies.net | Decatur | Georgia | 30033 | — |
| NeuroStudies.net | Lawrenceville | Georgia | 30045 | — |
| Alexian Brothers Medical Center | Elk Grove Village | Illinois | 60007 | — |
| Southern Illinois University School of Medicine Department | Springfield | Illinois | 62702 | — |
| Memorial Medical Center | Springfield | Illinois | 62781 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Lake Charles Clinical Trials | Lake Charles | Louisiana | 70629 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Massachusetts General Hosptial | Boston | Massachusetts | 02114 | — |
| Brigham & Womens Hospital | Boston | Massachusetts | 02115 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Boston Univeristy ADCRP | Boston | Massachusetts | 02118 | — |
| General Clincial Research Center (Infusion Location) | Boston | Massachusetts | 02118 | — |
| IDS Pharmacy (Drug Receipt). Attn:Hyesson Hong | Boston | Massachusetts | 02118 | — |
| Neuroscience Research of the Berkshires | Pittsfield | Massachusetts | 01201 | — |
| Shields MRI | Russells Mills | Massachusetts | 02747 | — |
| Springfield Neurology Associates, LLC | Springfield | Massachusetts | 01104 | — |
| University of Michigan Hospital and Health System | Ann Arbor | Michigan | 48105-2945 | — |
| University of Michigan Health System | Ann Arbor | Michigan | 48109-5872 | — |
| University of Michigan Health System | Ann Arbor | Michigan | 48109 | — |
| University of Michigan Health System | Ann Arbor | Michigan | 48110 | — |
| Michigan State University | East Lansing | Michigan | 48824 | — |
| Hattiesburg Clinic | Hattiesburg | Mississippi | 39401 | — |
| The Center for Pharmaceutical Research P.C. | Kansas City | Missouri | 64114 | — |
| Memory Enhancement Center of America, Inc. | Eatontown | New Jersey | 07724 | — |
| Pharmcare USA | Edison | New Jersey | 08837 | — |
| Alzheimer's Research Corp./Merician Institute for Aging | Paterson | New Jersey | 08759 | — |
| Neurological Care of Central New York | Liverpool | New York | 13088 | — |
| Carolina Neuropsychological Services, Inc | Raleigh | North Carolina | 27607 | — |
| Healthsouth Blue Ridge Surgery Center | Raleigh | North Carolina | 27607 | — |
| Raleigh Neurology Associates | Raleigh | North Carolina | 27607 | — |
| Wake Radiology Associates | Raleigh | North Carolina | 27607 | — |
| Ohio State University Imaging@Martha Moorehouse | Columbs | Ohio | 43210 | — |
| The Ohio State University | Columbs | Ohio | 43210 | — |
| The Ohio State University | Columbus | Ohio | 43210 | — |
| Summit Research Network(Oregon) Inc. | Portland | Oregon | 97210 | — |
| Providence Brain Institute | Portland | Oregon | 97225 | — |
| Providence Cognitive Assessment Clinic | Portland | Oregon | 97225 | — |
| Providence St. Vincent Medical Center | Portland | Oregon | 97225 | — |
| Dr. Michael Gabe (Clinic) | Silverton | Oregon | 97381 | — |
| Abington Memorial Hosptial | Abington | Pennsylvania | 19001 | — |
| Abington Neurological Associates | Abington | Pennsylvania | 19001 | — |
| Abington Neurological Assoc | Abington | Pennsylvania | 19001 | — |
| Andorra MRI of Flourtown | Flourtown | Pennsylvania | 19031 | — |
| The Clinical Trial Center, LLC | Jenkintown | Pennsylvania | 19046 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Investigational New Drug Services | Philadelphia | Pennsylvania | 19104 | — |
| University of Pennsylvania-Penn Memory Center | Philadelphia | Pennsylvania | 19104 | — |
| UPENN Clinical and Transitional Research Center | Philadelphia | Pennsylvania | 19104 | — |
| Jefferson Hospital for Neuroscience | Philadelphia | Pennsylvania | 19107 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Abington Neurological Associates | Willow Grove | Pennsylvania | 19090 | — |
| Rhode Island Mood and Memory Research Institute | East Providence | Rhode Island | 02914 | — |
| Simpson's Pharmacy | Pawtucket | Rhode Island | 02861 | — |
| Butler Hospital | Providence | Rhode Island | 02906 | — |
| Medical University of South Carolina Hospitals and Clinics | Charleston | South Carolina | 29425 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| MUSC | Charleston | South Carolina | 29425 | — |
| Medical University of South Carolina | North Charleston | South Carolina | 29406 | — |
| Texas Neurology, P.A. | Dallas | Texas | 75214 | — |
| Innovative Clinical Trials | San Antonio | Texas | 78229 | — |
| Integra Clinical Research | San Antonio | Texas | 78229 | — |
| Integra Clinical Research, LLC | San Antonio | Texas | 78231 | — |
| Integra Clinical Research | San Antonio | Texas | 78231 | — |
| Vista Infusions | San Antonio | Texas | 78231 | — |
| Inventive Infusion Solutions | San Antonio | Texas | 78258 | — |
| Inventive Infusions Solutions | San Antonio | Texas | 78258 | — |
| The Memory Clinic | Bennington | Vermont | 05201 | — |
| The Pharmacy | Bennington | Vermont | 05201 | — |
| Waisman Center (PET only) | Madison | Wisconsin | 53705-2280 | — |
| University of Wisconsin School of Medicine and Public Health | Madison | Wisconsin | 53705 | — |
| Wm S. Middleton Memorial Veterans Hospital | Madison | Wisconsin | 53705 | — |
| University of Wisconsin Hospitals and Clinics | Madison | Wisconsin | 53792 | — |
| University of Wisconsin School of Medicine and Public Health | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 177 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00676143, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 9, 2016 · Synced Jul 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00676143 live on ClinicalTrials.gov.