Phase III Lucanix™ Vaccine Therapy in Advanced Non-small Cell Lung Cancer (NSCLC) Following Front-line Chemotherapy
Public ClinicalTrials.gov record NCT00676507. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase III Study of Lucanix™ (Belagenpumatucel-L) in Advanced Non-small Cell Lung Cancer: An International Multicenter, Randomized, Double-blinded, Placebo-controlled Study of Lucanix™ Maintenance Therapy for Stages III/IV NSCLC Subjects Who Have Responded to or Have Stable Disease Following One Regimen of Front-line, Platinum-based Combination Chemotherapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Rationale: Vaccines made from gene-modified tumor cells may help the body build an immune response to kill tumor cells. It is not yet known whether vaccine therapy is more effective than a placebo as maintenance therapy in treatment of subjects with non-small cell lung cancer. Purpose: This randomized phase III trial is studying vaccine therapy to see how well it works compared with a placebo in treating subjects with stage III or stage IV non-small cell lung cancer.
Study identification
- NCT ID
- NCT00676507
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 532 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 2008 (Type not available)
- Primary completion
- Jan 2013 (Actual)
- Completion
- Jan 2013 (Actual)
- Last update posted
- May 8, 2015
2008 – 2013
United States locations
- U.S. sites
- 53
- U.S. states
- 29
- U.S. cities
- 49
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Southern Cancer Center | Mobile | Alabama | 36608 | — |
| Alaska Regional Hospital | Anchorage | Alaska | 99508 | — |
| Mayo Clinic Cancer Center | Scottsdale | Arizona | 85259 | — |
| Clopton Clinic Hematology/Oncology | Jonesboro | Arkansas | 72401 | — |
| Comprehensive Blood and Cancer Center | Bakersfield | California | 93309 | — |
| University of California, San Diego | La Jolla | California | 92093 | — |
| UCLA Pasadena Oncology | Pasadena | California | 91105 | — |
| Cancer Care Associates | Redondo | California | 90277 | — |
| Innovative Research Center of California | San Diego | California | 92103 | — |
| Sansum Clinic | Santa Barbara | California | 93105 | — |
| Santa Barbara Hematology Oncology Medical Group, Inc. | Santa Barbara | California | 93105 | — |
| Central Coast Medical Oncology Corporation | Santa Maria | California | 93454 | — |
| UCLA Cancer Center | Santa Monica | California | 90404 | — |
| UCLA Cancer Center-Valencia | Valencia | California | 91355 | — |
| UCLA Cancer Center | Westlake Village | California | 91361 | — |
| University of Colorado Health Science Center | Aurora | Colorado | 80045 | — |
| Pasco Hernando Oncology Associates, P.A. | Brooksville | Florida | 34613 | — |
| Medical Specialist of Palm Beaches | Lake Worth | Florida | 33467 | — |
| Ocala Oncology | Ocala | Florida | 34471 | — |
| Space Coast Medical Center | Titusville | Florida | 32796 | — |
| Atlanta Cancer Care | Roswell | Georgia | 30076 | — |
| Kootenai Cancer Center | Coeur d'Alene | Idaho | 83814q | — |
| St. Francis Medical Group Oncology and Hematology Specialists | Indianapolis | Indiana | 46237 | — |
| Iowa Blood and Cancer Center | Cedar Rapids | Iowa | 52402 | — |
| James Graham Brown Cancer Center | Louisville | Kentucky | 40202 | — |
| Hematology Oncology Life Center | Alexandria | Louisiana | 71301 | — |
| National Cancer Institute Center for Cancer Research, Medical Oncology Branch | Bethesda | Maryland | 20892-1182 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| University of Minnesota Medical Center | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic Cancer Center | Rochester | Minnesota | 55905 | — |
| University of Tennessee Cancer Institute | Southaven | Mississippi | 38671 | — |
| Comprehensive Cancer Centers of Nevada | Henderson | Nevada | 89052 | — |
| Comprehensive Cancer Centers of Nevada | Henderson | Nevada | 89074 | — |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89128 | — |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89169 | — |
| Cancer Center at Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Richmond University Medical Center | Staten Island | New York | 10310 | — |
| Eastchester Center for Cancer Care | The Bronx | New York | 10469 | — |
| Allergy Partners of West North Carolina | Asheville | North Carolina | 28801 | — |
| Cancer Care of WNC | Asheville | North Carolina | 28801 | — |
| Gabrail Cancer Center Research LLC | Canton | Ohio | 44718 | — |
| Optim Oncology | Midwest City | Oklahoma | 73110 | — |
| Cancer Center of the Carolinas | Greenville | South Carolina | 29605 | — |
| University of Tennessee Cancer Institute | Bartlett | Tennessee | 38133 | — |
| University of Tennessee Cancer Institute | Germantown | Tennessee | 38138 | — |
| University of Tennessee Cancer Institute | Memphis | Tennessee | 38104 | — |
| Texas Cancer Center Abilene, Texas Oncology P.A. | Abilene | Texas | 79606 | — |
| Mary Crowley Cancer Research Centers | Dallas | Texas | 75230 | — |
| Allison Cancer Center, Texas Oncology, P.A. | Midland | Texas | 79701 | — |
| Tyler Cancer Center, Texas Oncology | Tyler | Texas | 75702 | — |
| Seattle Cancer Care Alliance/Fred Hutchinson Cancer Res Ctr/Univ. of Washington Med Ctr | Seattle | Washington | 98109 | — |
| Davis Memorial Cancer Care Center | Elkins | West Virginia | 26241 | — |
| Marshfield Clinic Weston Center | Weston | Wisconsin | 54476 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 29 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00676507, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 8, 2015 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00676507 live on ClinicalTrials.gov.