Study to Evaluate Exemestane With and Without Entinostat (SNDX-275) in Treatment of Postmenopausal Women With Advanced Breast Cancer
Public ClinicalTrials.gov record NCT00676663. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-Blind, Multicenter Study of Exemestane With and Without SNDX-275 in Postmenopausal Women With Locally Recurrent or Metastatic Estrogen Receptor-Positive Breast Cancer, Progressing on Treatment With a Non-Steroidal Aromatase Inhibitor
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the safety and efficacy of entinostat in combination with exemestane in the treatment of advanced breast cancer.
Study identification
- NCT ID
- NCT00676663
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 130 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 13, 2008 (Actual)
- Primary completion
- Jan 29, 2011 (Actual)
- Completion
- Nov 26, 2012 (Actual)
- Last update posted
- May 11, 2022
2008 – 2012
United States locations
- U.S. sites
- 24
- U.S. states
- 15
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| California Cancer Care | Greenbrae | California | — | — |
| Moores UCSD Cancer Center | La Jolla | California | — | — |
| Scripps Health | La Jolla | California | — | — |
| University of Colorado | Aurora | Colorado | — | — |
| Rocky Mountain Cancer Center | Denver | Colorado | — | — |
| Florida Cancer Specialists | Fort Myers | Florida | — | — |
| Memorial Cancer Institute | Hollywood | Florida | — | — |
| University of Southern Florida -Moffitt Cancer Center | Tampa | Florida | — | — |
| Palm Beach Cancer Institute | West Palm Beach | Florida | — | — |
| Medical College of Georgia | Augusta | Georgia | — | — |
| Indiana University Indiana Cancer Pavilion | Indianapolis | Indiana | — | — |
| University of Maryland Greenebaum Cancer Center | Baltimore | Maryland | — | — |
| Kansas City Cancer Center | Kansas City | Missouri | — | — |
| Hematology-Oncology Associates of Northern New Jersey | Morristown | New Jersey | — | — |
| Carolinas Healthcare System Clinical Trials | Charlotte | North Carolina | — | — |
| Wake Forest University Baptist Medical Center | Winston-Salem | North Carolina | — | — |
| Oncology Hematology Care | Cincinnati | Ohio | — | — |
| Cancer Centers of the Carolinas | Greenville | South Carolina | — | — |
| Chattanooga Oncology Hematology Associates | Chattanooga | Tennessee | — | — |
| Sarah Cannon Cancer Center | Nashville | Tennessee | — | — |
| South Texas Cancer Center | McAllen | Texas | — | — |
| Virginia Cancer Institute | Richmond | Virginia | — | — |
| Columbia Basin Hematology & Oncology | Kennewick | Washington | — | — |
| Puget Sound Cancer Center | Seattle | Washington | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00676663, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 11, 2022 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00676663 live on ClinicalTrials.gov.