A Study of the Efficacy and Safety of Ocrelizumab in Patients With Relapsing-Remitting Multiple Sclerosis
Public ClinicalTrials.gov record NCT00676715. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase II, Multicenter, Randomized, Parallel-Group, Partially Blinded, Placebo and Avonex Controlled Dose Finding Study to Evaluate the Efficacy As Measured by Brain MRI Lesions, and Safety of 2 Dose Regimens of Ocrelizumab in Patients With RRMS
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a phase II, multicenter, randomized, parallel-group, partially blinded, placebo and Avonex (interferon beta-1a) controlled dose finding study to evaluate the efficacy as measured by brain MRI lesions, and safety of 2 dose regimens of ocrelizumab in participants with Relapsing Remitting Multiple Sclerosis (RRMS).
Study identification
- NCT ID
- NCT00676715
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 220 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 55 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 17, 2008 (Actual)
- Primary completion
- Mar 9, 2012 (Actual)
- Completion
- Nov 8, 2023 (Actual)
- Last update posted
- Dec 31, 2024
2008 – 2023
United States locations
- U.S. sites
- 26
- U.S. states
- 18
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Phoenix Neurological Associates Ltd | Phoenix | Arizona | 85006 | — |
| Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| East Bay Physicians Med Group;Sutter East Bay Med Foundation | Berkeley | California | 94705 | — |
| University of California San Francisco | San Francisco | California | 94117 | — |
| Advanced Neurology of Colorado, LLC | Fort Collins | Colorado | 80528 | — |
| Bradenton Research Center | Bradenton | Florida | 34205 | — |
| MS Center of Vero Beach | Vero Beach | Florida | 32960 | — |
| Shepherd Center; Multiple Sclerosis Center | Atlanta | Georgia | 30309 | — |
| University of Chicago; Neurology | Chicago | Illinois | 60637 | — |
| Kansas University Medical Center | Kansas City | Kansas | 66103 | — |
| John Hopkins University | Baltimore | Maryland | 21205 | — |
| Michigan Institute for Neurological Disorders | Farmington Hills | Michigan | 48334 | — |
| Dartmouth-Hitchcock Medical Center; Dept of Neurology | Lebanon | New Hampshire | 03756 | — |
| Columbia University Medical Center; The Neurological Institute of New York | New York | New York | 10032 | — |
| Island Neurological Associates, P.C. | Plainview | New York | 11803 | — |
| Suny At Stony Brook; Department Of Neurology | Stony Brook | New York | 11794 | — |
| The Neurological Institute PA | Charlotte | North Carolina | 28204 | — |
| Clinical Research of Winston Salem | Winston-Salem | North Carolina | 27103 | — |
| Cleveland Clinic | Cleveland | Ohio | 44106 | — |
| Ohio State University Med Ctr; MS Center | Columbus | Ohio | 43221 | — |
| Legacy Health System; Clinical Research & Tech Ctr | Tualatin | Oregon | 97062 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37212 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Integra Clinical Research, Llc | San Antonio | Texas | 78229 | — |
| Fletcher Allen Health Care/University of Vermont | Burlington | Vermont | 5405 | — |
| University of Virginia - Fontain Research Park | Charlottesville | Virginia | 22903 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 58 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00676715, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 31, 2024 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00676715 live on ClinicalTrials.gov.