Validation of Biomarkers in Amyotrophic Lateral Sclerosis (ALS)
Public ClinicalTrials.gov record NCT00677768. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter Study for the Validation of ALS Biomarkers
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to collect 650 blood and 300 cerebrospinal fluid (CSF) samples from people with amyotrophic lateral sclerosis (ALS), pure lower or upper motor neuron diseases, as well as other neurodegenerative diseases and from people with no neurological disorder. Through comparison of these samples, the researchers hope to learn more about the underlying cause of ALS, as well as find unique biological markers, which could be used to diagnose ALS and monitor disease progression. Additionally, up to 600 blood samples will be collected for a sub-study for DNA analysis. Studying components of the blood, such as DNA, may help us understand what happens when genes function abnormally and how it might be related to disease.
Study identification
- NCT ID
- NCT00677768
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 475 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 30 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2008 (Type not available)
- Primary completion
- Nov 2015 (Actual)
- Completion
- Nov 2015 (Actual)
- Last update posted
- Jun 3, 2016
2008 – 2015
United States locations
- U.S. sites
- 29
- U.S. states
- 19
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Phoenix Neurological Associates, Ltd. | Phoenix | Arizona | 85018 | — |
| University of California Irvine | Orange | California | 92868 | — |
| Mayo Clinic Neurology | Jacksonville | Florida | 32224 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Johns Hopkins University | Baltimore | Maryland | 21205 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02129 | — |
| Lahey Clinic | Burlington | Massachusetts | 01805 | — |
| Saint Mary's Healthcare | Grand Rapids | Michigan | 49503 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55404 | — |
| Saint Louis University | St Louis | Missouri | 63104 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Robert Wood Johnson/UMDNJ | New Brunswick | New Jersey | 08901 | — |
| Upstate Clinical Research, LLC | Albany | New York | 12205 | — |
| Beth Israel Medical Center, PACC | New York | New York | 10003 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| Carolinas Health Care | Charlotte | North Carolina | 28207 | — |
| Duke University Medical Center | Durham | North Carolina | 27705 | — |
| Wake Forest University | Winston-Salem | North Carolina | 27157 | — |
| OSU Medical Center | Columbus | Ohio | 43210 | — |
| Providence ALS Clinic | Portland | Oregon | 97213 | — |
| Oregon Health & Science University | Portland | Oregon | 97233 | — |
| Pennsylvania State University | Hershey | Pennsylvania | 17033 | — |
| Drexel University College of Medicine | Philadelphia | Pennsylvania | 19107 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Methodist Neurological Institute | Houston | Texas | 77030 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00677768, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 3, 2016 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00677768 live on ClinicalTrials.gov.