ClinicalTrials.gov record
Axitinib (AG 013736) As Second Line Therapy For Metastatic Renal Cell Cancer
ClinicalTrials.gov ID: NCT00678392
Public ClinicalTrials.gov record NCT00678392. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
AXITINIB (AG-013736) AS SECOND LINE THERAPY FOR METASTATIC RENAL CELL CANCER: AXIS TRIAL
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The study is designed to demonstrate that axitinib (AG-013736) is superior to sorafenib in delaying tumor progression in patients with metastatic renal cell cancer after failure of one first line regimen.
Study identification
- NCT ID
- NCT00678392
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 723 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 3, 2008 (Actual)
- Primary completion
- Aug 31, 2010 (Actual)
- Completion
- Feb 25, 2016 (Actual)
- Last update posted
- Jan 9, 2019
2008 – 2016
United States locations
- U.S. sites
- 161
- U.S. states
- 24
- U.S. cities
- 106
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| East Valley Hematology and Oncology Medical Group | Burbank | California | 91505 | — |
| Maurice Berkowtiz, MD | Burbank | California | 91505 | — |
| Agajanian Institute of Oncology and Hematology | Downey | California | 90241 | — |
| Los Angeles Hematology/Oncology Medical Group | Glendale | California | 91206 | — |
| Los Angeles Hematology/Oncology Medical Group | Los Angeles | California | 90017 | — |
| LAC-USC Medical Center | Los Angeles | California | 90033 | — |
| USC Norris Cancer Hospital and Clinics | Los Angeles | California | 90033 | — |
| Kenmar Research Institute | Los Angeles | California | 90057 | — |
| Metropolitan Hematology/Oncology Medical Group | Los Angeles | California | 90057 | — |
| Ronald Regan UCLA Medical Center | Los Angeles | California | 90095 | — |
| UCLA | Los Angeles | California | 90095 | — |
| Agajanian Institute of Oncology and Hematology | Montebello | California | 90640 | — |
| Brian LeBerthon, MD, A Medical Corporation | West Covina | California | 91790 | — |
| Agajanian Institute of Oncology and Hematology | Whittier | California | 90606 | — |
| Rocky Mountain Cancer Centers | Aurora | Colorado | 80012 | — |
| University of Colorado Cancer Center | Aurora | Colorado | 80045 | — |
| University of Colorado Denver: Division of Medical Oncology | Aurora | Colorado | 80045 | — |
| Rocky Mountain Cancer Centers | Boulder | Colorado | 80303 | — |
| Rocky Mountain Cancer Centers | Colorado Springs | Colorado | 80909 | — |
| Rocky Mountain Cancer Centers, LLP | Denver | Colorado | 80218 | — |
| Rocky Mountain Cancer Centers | Denver | Colorado | 80220 | — |
| Rocky Mountain Cancer Centers | Lakewood | Colorado | 80228 | — |
| Rocky Mountain Cancer Centers | Littleton | Colorado | 80120 | — |
| Rocky Mountain Cancer Centers | Lone Tree | Colorado | 80124 | — |
| Rocky Mountain Cancer Centers | Longmont | Colorado | 80501 | — |
| Rocky Mountain Cancer Centers | Parker | Colorado | 80138 | — |
| Rocky Mountain Cancer Centers | Thornton | Colorado | 80260 | — |
| Georgetown University Hospital, Lombardi Cancer Center | Washington D.C. | District of Columbia | 20007 | — |
| Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007 | — |
| Florida Cancer Specialists | Bonita Springs | Florida | 34135 | — |
| Florida Cancer Specialists | Bradenton | Florida | 34209 | — |
| Florida Cancer Specialists | Cape Coral | Florida | 33914 | — |
| Florida Cancer Specialists | Cape Coral | Florida | 33990 | — |
| University of Miami Sylvester at Deerfield Beach | Deerfield Beach | Florida | 33442 | — |
| Florida Cancer Specialists | Englewood | Florida | 34223 | — |
| Florida Cancer Specialists | Fort Myers | Florida | 33901 | — |
| Florida Cancer Specialists | Fort Myers | Florida | 33905 | — |
| Florida Cancer Specialists | Fort Myers | Florida | 33908 | — |
| Florida Cancer Specialists | Fort Myers | Florida | 33916 | — |
| University of Miami Hospital and Clinics | Miami | Florida | 33136 | — |
| Florida Cancer Specialists | Naples | Florida | 34102 | — |
| Florida Cancer Specialists | Naples | Florida | 34119 | — |
| M.D. Anderson Cancer Center Orlando | Orlando | Florida | 32806 | — |
| Orlando Regional Medical Center | Orlando | Florida | 32806 | — |
| Florida Cancer Specialists | Port Charlotte | Florida | 33980 | — |
| Florida Cancer Specialists | Sarasota | Florida | 34232 | — |
| Florida Cancer Specialists | Sarasota | Florida | 34236 | — |
| Florida Cancer Specialists | Venice | Florida | 34285 | — |
| Florida Cancer Specialists | Venice | Florida | 34292 | — |
| Peachtree Hematology-Oncology Consultants, P.C. | Atlanta | Georgia | 30318 | — |
| Chattanooga Oncology and Hematology Associates, PC | Ringgold | Georgia | 30736 | — |
| Mountain States Tumor Institute | Boise | Idaho | 83712 | — |
| Mountain States Tumor Institute | Fruitland | Idaho | 83619 | — |
| Mountain States Tumor Institute | Meridian | Idaho | 83642 | — |
| Mountain States Tumor Institute | Nampa | Idaho | 83686 | — |
| Mountain States Tumor Institute | Twin Falls | Idaho | 83301 | — |
| Loyola University Chicago Cardinal Bernardin Cancer Center | Maywood | Illinois | 60153 | — |
| Cental Indiana Cancer Centers | Carmel | Indiana | 46032 | — |
| Central Indiana Cancer Centers | Fishers | Indiana | 46037 | — |
| Cental Indiana Cancer Centers | Greenfield | Indiana | 46140 | — |
| Central Indiana Cancer Centers | Indianapolis | Indiana | 46219 | — |
| Central Indiana Cancer Centers | Indianapolis | Indiana | 46227 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| University of Michigan Health System | Ann Arbor | Michigan | 48109-5948 | — |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Weisberg Cancer Treatment Center | Farmington Hills | Michigan | 48334 | — |
| University of Minnesota Medical Center Fairview | Minneapolis | Minnesota | 55455 | — |
| Missouri Cancer Associates | Columbia | Missouri | 65201 | — |
| St. John's Mercy Medical Center | St Louis | Missouri | 63141 | — |
| St. John's Mercy, David C. Pratt Cancer Center | St Louis | Missouri | 63141 | — |
| St. John's Mercy Medical Center | Washington | Missouri | 63090 | — |
| Comprehensive Cancer Centers of Nevada | Henderson | Nevada | 89052 | — |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89128 | — |
| Nevada Cancer Institute | Las Vegas | Nevada | 89135 | — |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89148 | — |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89169 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| The Cancer Center at Hackensack University Medical Center - The Hillcrest Building | Hackensack | New Jersey | 07601 | — |
| The Cancer Center at Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Memorial Sloan Kettering Cancer Center - Sidney Kimmel Center | New York | New York | 10065 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | — |
| Department of Medicine MSG @ SUNY HSC @ Syrcacuse, Inc. | Oneida | New York | 13421 | — |
| Department of Medicine MSG @ SUNY HSC @ Syracuse, Inc. | Oswego | New York | 13126 | — |
| Suny Upstate Medical University | Syracuse | New York | 13210-2306 | — |
| Department of Medicine MSG @ SUNY HSC @ Syracuse, Inc | Syracuse | New York | 13210 | — |
| Montefiore Medical Center | The Bronx | New York | 10466 | — |
| Raleigh Hematology Oncology Associates, DBA | Cary | North Carolina | 27518 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Investigational Chemotherapy Services | Durham | North Carolina | 27710 | — |
| Albermarie Hospitals | Elizabeth City | North Carolina | 27909 | — |
| Virginia Oncology Associates | Elizabeth City | North Carolina | 27909 | — |
| Raleigh Hematology Oncology Associates, P.C. | Raleigh | North Carolina | 27607 | — |
| Case Western Reserve University | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Ohio State University Arthur G. James Cancer Hospital and Richard J. Solove Research Institute | Columbus | Ohio | 43210 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| James Care in Kenny | Columbus | Ohio | 43211 | — |
| Monarch | Mayfield Heights | Ohio | 44124 | — |
| Lake University - Ireland Cancer Center (LUICC) | Mentor | Ohio | 44060 | — |
| UHHS - Chagrin Highlands | Orange | Ohio | 44122 | — |
| UHHS - Westlake | Westlake | Ohio | 44145 | — |
| Oncology Associates of Oregon, P.C. | Eugene | Oregon | 97401-8122 | — |
| Willamette Valley Cancer Institute and Research Center | Springfield | Oregon | 97477 | — |
| Penn State Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111-2497 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Cancer Centers of the Carolinas | Easley | South Carolina | 29605 | — |
| Cancer Centers of the Carolinas | Greenville | South Carolina | 29605 | — |
| Hematology and Oncology Associates of SC, LLC - Eastside Medical Center | Greenville | South Carolina | 29615 | — |
| Cancer Centers of the Carolinas, Seneca | Seneca | South Carolina | 29672 | — |
| Cancer Centers of the Carolinas | Spartanburg | South Carolina | 29307 | — |
| Chattanooga Oncology and Hematology Associates, PC | Chattanooga | Tennessee | 37404 | — |
| Chattanooga Oncology Hematology Associates P.C. | Chattanooga | Tennessee | 37404 | — |
| Tennessee Oncology, PLLC | Franklin | Tennessee | 37067 | — |
| Vanderbilt-Ingram Cancer Center-Cool Springs | Franklin | Tennessee | 37067 | — |
| Tennessee Oncology, PLLC | Gallatin | Tennessee | 37066 | — |
| Tennessee Oncology, PLLC | Hermitage | Tennessee | 37076 | — |
| Chattanooga Oncology & Hematology Associates | Hixson | Tennessee | 37343 | — |
| Tennessee Oncology, PLLC | Lebanon | Tennessee | 37087 | — |
| Tennessee Oncology, PLLC | Murfreesboro | Tennessee | 37130 | — |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37203 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37205 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37207 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37211 | — |
| Vanderbilt-Ingram Cancer Center | Nashville | Tennessee | 37232-6307 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Tennessee Oncology, PLLC | Smyrna | Tennessee | 37167 | — |
| Texas Oncology - Austin Midtown | Austin | Texas | 78705 | — |
| Texas Oncology - Central Midtown | Austin | Texas | 78705 | — |
| Texas Oncology - Austin Central | Austin | Texas | 78731 | — |
| Texas Oncology - South Austin | Austin | Texas | 78745 | — |
| Texas Oncolgoy - Austin North | Austin | Texas | 78758 | — |
| Texas Oncology - Austin Northwest | Austin | Texas | 78759 | — |
| Texas Oncology, P.A. | Bedford | Texas | 76022 | — |
| Texas Oncology - Cedar Park | Cedar Park | Texas | 78613 | — |
| Texas Oncology - Baylor Charles A. Sammons Cancer Center | Dallas | Texas | 75246 | — |
| Investigation Products Center (IPC) | Fort Worth | Texas | 76177 | — |
| Investigational Products Center (IPC) | Fort Worth | Texas | 76177 | — |
| US Oncology Research and Clinical Pharmacy | Fort Worth | Texas | 76177 | — |
| Genitourinary Cancer Center | Houston | Texas | 77030 | — |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Texas Oncology - Seton Williamson | Round Rock | Texas | 78655 | — |
| Texas Oncology - Round Rock | Round Rock | Texas | 78681 | — |
| Texas Oncology, P.A. | Tyler | Texas | 75702 | — |
| Deke Slayton Cancer Center | Webster | Texas | 77598-4420 | — |
| Texas Oncology - Clear Lake | Webster | Texas | 77598 | — |
| Virginia Cancer Specialists, PC | Arlington | Virginia | 22205 | — |
| Virginia Oncology Associates | Chesapeake | Virginia | 23320 | — |
| Virginia Cancer Specialists, PC | Fairfax | Virginia | 22031 | — |
| Virginia Cancer Specialists, PC | Gainesville | Virginia | 20155 | — |
| Virginia Oncology Associates | Hampton | Virginia | 23666 | — |
| Virginia Cancer Specialists, PC | Leesburg | Virginia | 20176 | — |
| Virginia Oncology Associates | Newport News | Virginia | 23606 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
| Virginia Oncology Associates | Virginia Beach | Virginia | 23456 | — |
| Virginia Cancer Specialists, PC | Woodbridge | Virginia | 22191 | — |
| Virginia Mason Medical Center, Section of Hematology/Oncology | Seattle | Washington | 98101 | — |
| Seattle Cancer Care Alliance | Seattle | Washington | 98109-1023 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 133 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00678392, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 9, 2019 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00678392 live on ClinicalTrials.gov.