A Phase I/II Study of Carboplatin and Etoposide With or Without Obatoclax in Extensive-stage Small Cell Lung Cancer (ES-SCLC)
Public ClinicalTrials.gov record NCT00682981. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Phase I Followed by a Randomized, Phase II Study of Carboplatin and Etoposide With or Without Obatoclax Administered Every 3 Weeks to Patients With Extensive- Stage Small Cell Lung Cancer (ES-SCLC)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The Phase I portion of this protocol will determine the best phase II dose and schedule of obatoclax with carboplatin and etoposide in patients with extensive-stage small cell lung cancer. The Phase II portion will evaluate the response rate to this regimen.
Study identification
- NCT ID
- NCT00682981
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 218 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2008 (Type not available)
- Primary completion
- Nov 2011 (Actual)
- Completion
- Nov 2011 (Actual)
- Last update posted
- Jul 21, 2016
2008 – 2011
United States locations
- U.S. sites
- 32
- U.S. states
- 20
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clearview Cancer Institute | Huntsville | Alabama | 35805 | — |
| Northwest Alabama Cancer Center | Muscle Shoals | Alabama | 35661 | — |
| Mayo Clinic-Arizona | Scottsdale | Arizona | 85259 | — |
| Arizona Clinical Research Center | Tucson | Arizona | 85715 | — |
| City of Hope and Beckman Research Institute | Duarte | California | 91010 | — |
| University of California-San Diego Moores Cancer Center | La Jolla | California | 92093-0987 | — |
| Georgetown University Hospital-Lombardi Comprehensive Cancer Center | Washington D.C. | District of Columbia | 20007 | — |
| Integrated Community Oncology Network | Jacksonville | Florida | 32256 | — |
| University of Miami-Sylvester Cancer Center | Miami | Florida | 33136 | — |
| Florida Cancer Institute | New Port Richey | Florida | 34655-1112 | — |
| H. Lee Moffitt Cancer Center | Tampa | Florida | 33612 | — |
| Northwest Georgia Oncology Centers | Marietta | Georgia | 30060 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Iowa Blood and Cancer Center, PLC | Cedar Rapids | Iowa | 52402 | — |
| Cancer Center of Kansas | Wichita | Kansas | 67214 | — |
| James Brown Cancer Center | Louisville | Kentucky | 40202 | — |
| Center for Cancer and Blood Disorders | Bethesda | Maryland | 20817 | — |
| Kalamazoo Hematology and Oncology | Kalamazoo | Michigan | 49048 | — |
| Mid Ohio Oncology/Hematology, Inc. | Columbus | Ohio | 43219 | — |
| Cancer Care Associates-Oklahoma City | Oklahoma City | Oklahoma | 73112 | — |
| Cancer Care Associates-Tulsa | Tulsa | Oklahoma | 74136 | — |
| University of Pennsylvania Abramson Cancer Center | Philadelphia | Pennsylvania | 19104 | — |
| Greater Philadelphia Cancer and Hematology Specialists | Philadelphia | Pennsylvania | 19114 | — |
| Cancer Centers of the Carolinas | Greenville | South Carolina | 29605 | — |
| McLeod Cancer & Blood Center | Johnson City | Tennessee | 37604 | — |
| The West Clinic | Memphis | Tennessee | 38120 | — |
| Baylor | Dallas | Texas | 75246 | — |
| UT Southwestern Medical Center at Dallas | Dallas | Texas | 75390-8852 | — |
| Tyler Cancer Center | Tyler | Texas | 75702 | — |
| Peninsula Cancer Institute | Newport News | Virginia | 23601 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
| Wheeling Hospital | Wheeling | West Virginia | 26003 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 43 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00682981, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 21, 2016 · Synced Nov 5, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00682981 live on ClinicalTrials.gov.