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Completed Phase 1Phase 2 Interventional

A Phase I/II Study of Carboplatin and Etoposide With or Without Obatoclax in Extensive-stage Small Cell Lung Cancer (ES-SCLC)

ClinicalTrials.gov ID: NCT00682981

Public ClinicalTrials.gov record NCT00682981. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 20, 2026, 3:31 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase I Followed by a Randomized, Phase II Study of Carboplatin and Etoposide With or Without Obatoclax Administered Every 3 Weeks to Patients With Extensive- Stage Small Cell Lung Cancer (ES-SCLC)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The Phase I portion of this protocol will determine the best phase II dose and schedule of obatoclax with carboplatin and etoposide in patients with extensive-stage small cell lung cancer. The Phase II portion will evaluate the response rate to this regimen.

Study identification

NCT ID
NCT00682981
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Gemin X
Industry
Enrollment
218 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 30, 2008
Primary completion
Oct 31, 2011
Completion
Oct 31, 2011
Last update posted
Jul 20, 2016

2008 – 2011

United States locations

U.S. sites
32
U.S. states
20
U.S. cities
30
Facility City State ZIP Site status
Clearview Cancer Institute Huntsville Alabama 35805
Northwest Alabama Cancer Center Muscle Shoals Alabama 35661
Mayo Clinic-Arizona Scottsdale Arizona 85259
Arizona Clinical Research Center Tucson Arizona 85715
City of Hope and Beckman Research Institute Duarte California 91010
University of California-San Diego Moores Cancer Center La Jolla California 92093-0987
Georgetown University Hospital-Lombardi Comprehensive Cancer Center Washington D.C. District of Columbia 20007
Integrated Community Oncology Network Jacksonville Florida 32256
University of Miami-Sylvester Cancer Center Miami Florida 33136
Florida Cancer Institute New Port Richey Florida 34655-1112
H. Lee Moffitt Cancer Center Tampa Florida 33612
Northwest Georgia Oncology Centers Marietta Georgia 30060
University of Chicago Chicago Illinois 60637
Iowa Blood and Cancer Center, PLC Cedar Rapids Iowa 52402
Cancer Center of Kansas Wichita Kansas 67214
James Brown Cancer Center Louisville Kentucky 40202
Center for Cancer and Blood Disorders Bethesda Maryland 20817
Kalamazoo Hematology and Oncology Kalamazoo Michigan 49048
Mid Ohio Oncology/Hematology, Inc. Columbus Ohio 43219
Cancer Care Associates-Oklahoma City Oklahoma City Oklahoma 73112
Cancer Care Associates-Tulsa Tulsa Oklahoma 74136
University of Pennsylvania Abramson Cancer Center Philadelphia Pennsylvania 19104
Greater Philadelphia Cancer and Hematology Specialists Philadelphia Pennsylvania 19114
Cancer Centers of the Carolinas Greenville South Carolina 29605
McLeod Cancer & Blood Center Johnson City Tennessee 37604
The West Clinic Memphis Tennessee 38120
Baylor Dallas Texas 75246
UT Southwestern Medical Center at Dallas Dallas Texas 75390-8852
Tyler Cancer Center Tyler Texas 75702
Peninsula Cancer Institute Newport News Virginia 23601
Virginia Oncology Associates Norfolk Virginia 23502
Wheeling Hospital Wheeling West Virginia 26003

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 43 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00682981, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 20, 2016 · Synced Sep 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00682981 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →