A Study of IMC-A12 or Ramucirumab Plus Mitoxantrone and Prednisone in Prostate Cancer
Public ClinicalTrials.gov record NCT00683475. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Randomized Study of IMC-A12 or IMC-1121B Plus Mitoxantrone and Prednisone in Metastatic Androgen-Independent Prostate Cancer (AIPC) Following Disease Progression on Docetaxel-Based Chemotherapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether IMC-A12 or IMC-1121B (ramucirumab) with Mitoxantrone and Prednisone is effective in the treatment of metastatic androgen- independent prostate cancer (APIC).
Study identification
- NCT ID
- NCT00683475
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 138 participants
Conditions and interventions
Conditions
Interventions
- IMC-A12 Biological
- Mitoxantrone Drug
- Prednisone Drug
- IMC-1121B (ramucirumab) Biological
Biological · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2008 (Type not available)
- Primary completion
- Sep 2011 (Actual)
- Completion
- Sep 2011 (Actual)
- Last update posted
- Oct 16, 2014
2008 – 2011
United States locations
- U.S. sites
- 36
- U.S. states
- 21
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| ImClone Investigational Site | La Jolla | California | 92093 | — |
| ImClone Investigational Site | New Haven | Connecticut | 06520 | — |
| ImClone Investigational Site | Boca Raton | Florida | 33486 | — |
| ImClone Investigational Site | Port Saint Lucie | Florida | 34952 | — |
| ImClone Investigational Site | Atlanta | Georgia | 30318 | — |
| ImClone Investigational Site | Chicago | Illinois | 60611 | — |
| ImClone Investigational Site | Chlcago | Illinois | 60637 | — |
| ImClone Investigational Site | Evanston | Illinois | 60201 | — |
| ImClone Investigational Site | Maryville | Illinois | 62062 | — |
| ImClone Investigational Site | Cedar Rapids | Iowa | 52402 | — |
| ImClone Investigational Site | Metairie | Louisiana | 70006 | — |
| ImClone Investigational Site | Ann Arbor | Michigan | 48109 | — |
| ImClone Investigational Site | Rochester | Minnesota | 55905 | — |
| ImClone Investigational Site | St Louis | Missouri | 63110 | — |
| ImClone Investigational Site | Billings | Montana | 59101 | — |
| ImClone Investigational Site | Roseland | New Jersey | 07068 | — |
| ImClone Investigational Site | Buffalo | New York | 14263 | — |
| ImClone Investigational Site | East Setauket | New York | 11733 | — |
| ImClone Investigational Site | New York | New York | 10016 | — |
| ImClone Investigational Site | New York | New York | 10019 | — |
| ImClone Investigational Site | New York | New York | 10021 | — |
| ImClone Investigational Site | New York | New York | 10032 | — |
| ImClone Investigational Site | Durham | North Carolina | 27710 | — |
| ImClone Investigational Site | Cleveland | Ohio | 44195 | — |
| ImClone Investigational Site | Philadelphia | Pennsylvania | 19111 | — |
| ImClone Investigational Site | Pittsburgh | Pennsylvania | 15232 | — |
| ImClone Investigational Site | Greenville | South Carolina | 29605 | — |
| ImClone Investigational Site | Knoxville | Tennessee | 37920 | — |
| ImClone Investigational Site | Nashville | Tennessee | 37203 | — |
| ImClone Investigational Site | Abilene | Texas | 79606 | — |
| ImClone Investigational Site | Dallas | Texas | 75246 | — |
| ImClone Investigational Site | Houston | Texas | 77030-4009 | — |
| ImClone Investigational Site | Houston | Texas | 77030 | — |
| ImClone Investigational Site | Seattle | Washington | 98104 | — |
| ImClone Investigational Site | Seattle | Washington | 98109 | — |
| ImClone Investigational Site | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00683475, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 16, 2014 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00683475 live on ClinicalTrials.gov.