A Study to Evaluate the Safety, Tolerability, Immunogenicity and Vaccine-like Viral Shedding of MEDI-534, Against Respiratory Syncytial Virus (RSV) and Parainfluenza Virus Type 3 (PIV3), in Healthy 6 to <24 Month-old Children and in 2 Month-old Infants
Public ClinicalTrials.gov record NCT00686075. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2a, Randomized, Double-blind, Placebo-controlled, Dose-escalation Study to Evaluate the Safety, Tolerability, Immunogenicity and Vaccine-like Viral Shedding of MEDI-534, a Live, Attenuated Intranasal Vaccine Against Respiratory Syncytial Virus (RSV) and Parainfluenza Virus Type 3 (PIV3), in Healthy 6 to < 24 Month-old Children and in 2 Month-old Infants
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Primary objective of this study is to describe the safety and tolerability of multiple doses of MEDI-534 in children 6 to less than (\<) 24 months of age and in infants 2 months of age.
Study identification
- NCT ID
- NCT00686075
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 1,338 participants
Conditions and interventions
Conditions
Interventions
- MEDI-534, Cohort 1 Biological
- Placebo, Cohort 1 Other
- MEDI-534, Cohort 2 Biological
- Placebo, Cohort 2 Other
- MEDI-534, Cohort 3 Biological
- Placebo, Cohort 3 Other
- MEDI-534, Cohort 4 Biological
- Placebo, Cohort 4 Other
- MEDI-534, Cohort 5 Biological
- Placebo, Cohort 5 Other
Biological · Other
Eligibility (public fields only)
- Age range
- 2 Months to 23 Months
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2008 (Type not available)
- Primary completion
- Aug 2012 (Actual)
- Completion
- Aug 2012 (Actual)
- Last update posted
- Sep 26, 2014
2008 – 2012
United States locations
- U.S. sites
- 51
- U.S. states
- 24
- U.S. cities
- 47
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Mobile | Alabama | — | — |
| Research Site | Bentonville | Arkansas | 72712 | — |
| Research Site | Little Rock | Arkansas | 72202 | — |
| Research Site | Anaheim | California | 92801 | — |
| Research Site | Anaheim | California | — | — |
| Research Site | Bell Gardens | California | 90201 | — |
| Research Site | Downey | California | 90241 | — |
| Research Site | Lakewood | California | 90712 | — |
| Research Site | Long Beach | California | — | — |
| Research Site | Paramount | California | 90723 | — |
| Research Site | San Diego | California | 92103 | — |
| Research Site | West Covina | California | 91790 | — |
| Research Site | Thornton | Colorado | — | — |
| Research Site | Gainesville | Florida | 32607 | — |
| Research Site | Tampa | Florida | 33606 | — |
| Research Site | Dalton | Georgia | 30721 | — |
| Research Site | Chicago | Illinois | 60614 | — |
| Research Site | Kansas City | Kansas | — | — |
| Research Site | Topeka | Kansas | 66604 | — |
| Research Site | Lexington | Kentucky | 40503 | — |
| Research Site | Paducah | Kentucky | 42003 | — |
| Research Site | Shreveport | Louisiana | — | — |
| Research Site | Saint Paul | Minnesota | 55108 | — |
| Research Site | Bridgeton | Missouri | 63044 | — |
| Research Site | Omaha | Nebraska | 68131 | — |
| Research Site | Omaha | Nebraska | 68134 | — |
| Research Site | Las Vegas | Nevada | — | — |
| Research Site | Brooklyn | New York | — | — |
| Research Site | Johnson City | New York | — | — |
| Research Site | Lake Success | New York | 11042 | — |
| Research Site | Stony Brook | New York | 11794-8111 | — |
| Research Site | Syracuse | New York | 13210 | — |
| Research Site | New Bern | North Carolina | 28562 | — |
| Research Site | Cincinnati | Ohio | 45229 | — |
| Research Site | Gresham | Oregon | 97030 | — |
| Research Site | Pittsburgh | Pennsylvania | — | — |
| Research Site | Sellersville | Pennsylvania | 18960 | — |
| Research Site | Jackson | Tennessee | 38305 | — |
| Research Site | Amarillo | Texas | — | — |
| Research Site | Dallas | Texas | — | — |
| Research Site | Houston | Texas | 77030 | — |
| Research Site | Poteet | Texas | — | — |
| Research Site | San Antonio | Texas | 78229 | — |
| Research Site | San Antonio | Texas | 78258 | — |
| Research Site | San Antonio | Texas | — | — |
| Research Site | Tomball | Texas | 77070 | — |
| Research Site | Layton | Utah | 84041 | — |
| Research Site | Orem | Utah | 84058 | — |
| Research Site | St. George | Utah | 84790 | — |
| Research Site | Midlothian | Virginia | 23113 | — |
| Research Site | Huntington | West Virginia | 25701 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 49 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00686075, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 26, 2014 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00686075 live on ClinicalTrials.gov.