A Study to Assess the Effect of RO4607381 in Patients With Relatively Low Levels of High Density Lipoprotein-Cholesterol (HDL-C)
Public ClinicalTrials.gov record NCT00697203. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind Study of the Effect of RO4607381 in Combination With Pravastatin on HDL-cholesterol (HDL-C) Levels in Patients With Low or Average HDL-C Levels
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This 4 arm study will evaluate the efficacy and safety of RO4607381 when co-administered with pravastatin in patients with low or relatively low HDL-C levels. Patients will be randomised to one of 4 groups to receive either RO4607381 300mg, 600mg or 900mg po daily, or placebo po daily, for 12 weeks.All patients will also receive pravastatin 40mg po daily for 12 weeks.The anticipated time on study treatment is 3 months and the target sample size is 100-500 individuals.
Study identification
- NCT ID
- NCT00697203
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 292 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 2005 (Type not available)
- Primary completion
- May 2006 (Actual)
- Completion
- May 2006 (Actual)
- Last update posted
- Jan 2, 2020
2005 – 2006
United States locations
- U.S. sites
- 33
- U.S. states
- 22
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Mobile | Alabama | 36608 | — |
| Not listed | Scottsdale | Arizona | 85251 | — |
| Not listed | Newark | Delaware | 19713 | — |
| Not listed | Miami | Florida | 33137 | — |
| Not listed | Chicago | Illinois | 60610-4319 | — |
| Not listed | Evansville | Indiana | 47714 | — |
| Not listed | Indianapolis | Indiana | 46260 | — |
| Not listed | Iowa City | Iowa | 52242 | — |
| Not listed | Overland Park | Kansas | 66215 | — |
| Not listed | Wichita | Kansas | 67207 | — |
| Not listed | Louisville | Kentucky | 40213 | — |
| Not listed | Chalmette | Louisiana | 70043 | — |
| Not listed | Slidell | Louisiana | 70458 | — |
| Not listed | Auburn | Maine | 04210 | — |
| Not listed | Scarborough | Maine | 04074 | — |
| Not listed | Baltimore | Maryland | 21201 | — |
| Not listed | Bethesda | Maryland | 20817 | — |
| Not listed | Towson | Maryland | 21204 | — |
| Not listed | St Louis | Missouri | 63110 | — |
| Not listed | Concord | New Hampshire | 03301 | — |
| Not listed | Charlotte | North Carolina | 28209 | — |
| Not listed | Statesville | North Carolina | 28677 | — |
| Not listed | Winston-Salem | North Carolina | 27103 | — |
| Not listed | Cincinnati | Ohio | 45212 | — |
| Not listed | Springdale | Ohio | 45246 | — |
| Not listed | Oklahoma City | Oklahoma | 73103 | — |
| Not listed | Philadelphia | Pennsylvania | 19107 | — |
| Not listed | Warminster | Pennsylvania | 18974 | — |
| Not listed | Fort Worth | Texas | 76107 | — |
| Not listed | Houston | Texas | 77030 | — |
| Not listed | Richmond | Virginia | 23294 | — |
| Not listed | Seattle | Washington | 98104 | — |
| Not listed | Madison | Wisconsin | 53719 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00697203, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 2, 2020 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00697203 live on ClinicalTrials.gov.