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Completed Phase 1 Interventional

Safety Study of Oral MGCD265 Administered Without Interruption to Subjects With Advanced Malignancies

ClinicalTrials.gov ID: NCT00697632

Public ClinicalTrials.gov record NCT00697632. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 9, 2026, 11:26 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Open-Label Dose-Escalation Trial to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Daily Oral MGCD265 Administered Without Interruption to Subjects With Advanced Malignancies

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

In this study, MGCD265, a new anticancer drug under investigation, is given daily to patients with advanced malignancies to study its safety profile.

Study identification

NCT ID
NCT00697632
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Mirati Therapeutics Inc.
Industry
Enrollment
180 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 31, 2008
Primary completion
Aug 31, 2018
Completion
Dec 31, 2018
Last update posted
Feb 11, 2019

2008 – 2019

United States locations

U.S. sites
12
U.S. states
10
U.S. cities
12
Facility City State ZIP Site status
City of Hope Duarte California 91010
UC Irvine Medical Center Orange California 92868
UC San Diego San Diego California 92093
University of Chicago Chicago Illinois 60637
Dana-Farber Cancer Institute Boston Massachusetts 02115
Washington University, Alvin J. Siteman Cancer Center St Louis Missouri 63110
Columbia University, Herbert Irving Comprehensive Cancer Center New York New York 10032
Duke University Medical Center Durham North Carolina 27710
Fox Chase Cancer Center Philadelphia Pennsylvania 19111
University of Texas, MD Anderson Cancer Center Houston Texas 77030
Huntsman Cancer Institute Salt Lake City Utah 84112
Seattle Cancer Care Alliance Seattle Washington 98109

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00697632, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 11, 2019 · Synced Sep 9, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00697632 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →