ClinicalTrials.gov record
Pemetrexed and/or Sunitinib as Second-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer
ClinicalTrials.gov ID: NCT00698815
Public ClinicalTrials.gov record NCT00698815. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Phase II Study to Assess the Efficacy of Pemetrexed or Sunitinib (NSC # 736511) or Pemetrexed Plus Sunitinib in the Second-Line Treatment of Advanced Non-small Cell Lung Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This randomized phase II trial studies pemetrexed disodium and sunitinib malate to compare how well they work when given alone or together as second-line therapy in treating patients with stage IIIB or stage IV non-small cell lung cancer. Drugs used in chemotherapy, such as pemetrexed disodium, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Sunitinib malate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. It is not yet known whether pemetrexed disodium and sunitinib malate are more effective when given alone or together in treating non-small cell lung cancer.
Study identification
- NCT ID
- NCT00698815
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 130 participants
Conditions and interventions
Conditions
Interventions
- Laboratory Biomarker Analysis Other
- Pemetrexed Disodium Drug
- Sunitinib Malate Drug
Other · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 15, 2008 (Actual)
- Primary completion
- Dec 1, 2011 (Actual)
- Completion
- Not listed
- Last update posted
- Feb 8, 2022
Started 2008
United States locations
- U.S. sites
- 129
- U.S. states
- 26
- U.S. cities
- 93
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Kaiser Permanente-Anaheim | Anaheim | California | 92807 | — |
| Arroyo Grande Community | Arroyo Grande | California | 93420 | — |
| Kaiser Permanente-Baldwin Park | Baldwin Park | California | 91706 | — |
| Kaiser Permanente-Bellflower | Bellflower | California | 90706 | — |
| East Bay Radiation Oncology Center | Castro Valley | California | 94546 | — |
| Eden Hospital Medical Center | Castro Valley | California | 94546 | — |
| Valley Medical Oncology Consultants-Castro Valley | Castro Valley | California | 94546 | — |
| Bay Area Breast Surgeons Inc | Emeryville | California | 94608 | — |
| Kaiser Permanente Hospital | Fontana | California | 92335 | — |
| Valley Medical Oncology Consultants-Fremont | Fremont | California | 94538 | — |
| Kaiser Permanente - Harbor City | Harbor City | California | 90710 | — |
| Kaiser Permanente-Irvine | Irvine | California | 92618 | — |
| Kaiser Permanente Los Angeles Medical Center | Los Angeles | California | 90027 | — |
| Kaiser Permanente-Cadillac | Los Angeles | California | 90034 | — |
| Contra Costa Regional Medical Center | Martinez | California | 94553-3156 | — |
| El Camino Hospital | Mountain View | California | 94040 | — |
| Highland General Hospital | Oakland | California | 94602 | — |
| Alta Bates Summit Medical Center - Summit Campus | Oakland | California | 94609 | — |
| Bay Area Tumor Institute | Oakland | California | 94609 | — |
| Hematology and Oncology Associates-Oakland | Oakland | California | 94609 | — |
| Tom K Lee Inc | Oakland | California | 94609 | — |
| Kaiser Permanente - Panorama City | Panorama City | California | 91402 | — |
| PCR Oncology | Pismo Beach | California | 93449 | — |
| Valley Care Health System - Pleasanton | Pleasanton | California | 94588 | — |
| Valley Medical Oncology Consultants | Pleasanton | California | 94588 | — |
| Kaiser Permanente-Riverside | Riverside | California | 92505 | — |
| University of California San Diego | San Diego | California | 92103 | — |
| Kaiser Permanente-San Diego Mission | San Diego | California | 92108 | — |
| Kaiser Permanente-San Diego Zion | San Diego | California | 92120 | — |
| Kaiser Permanente-San Marcos | San Marcos | California | 92069 | — |
| Doctors Medical Center- JC Robinson Regional Cancer Center | San Pablo | California | 94806 | — |
| Kaiser Permanente | Woodland Hills | California | 91367 | — |
| Hartford Hospital | Hartford | Connecticut | 06102 | — |
| Middlesex Hospital | Middletown | Connecticut | 06457 | — |
| Norwalk Hospital | Norwalk | Connecticut | 06856 | — |
| Beebe Medical Center | Lewes | Delaware | 19958 | — |
| Christiana Care Health System-Christiana Hospital | Newark | Delaware | 19718 | — |
| MedStar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| MedStar Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| Holy Cross Hospital | Fort Lauderdale | Florida | 33308 | — |
| Jupiter Medical Center | Jupiter | Florida | 33458 | — |
| Mount Sinai Medical Center | Miami Beach | Florida | 33140 | — |
| Jesse Brown Veterans Affairs Medical Center | Chicago | Illinois | 60612 | — |
| University of Illinois | Chicago | Illinois | 60612 | — |
| University of Chicago Comprehensive Cancer Center | Chicago | Illinois | 60637 | — |
| Joliet Oncology-Hematology Associates Limited | Joliet | Illinois | 60435 | — |
| AMITA Health Adventist Medical Center | La Grange | Illinois | 60525 | — |
| Elkhart Clinic | Elkhart | Indiana | 46514-2098 | — |
| Michiana Hematology Oncology PC-Elkhart | Elkhart | Indiana | 46514 | — |
| Elkhart General Hospital | Elkhart | Indiana | 46515 | — |
| Community Howard Regional Health | Kokomo | Indiana | 46904 | — |
| IU Health La Porte Hospital | La Porte | Indiana | 46350 | — |
| Michiana Hematology Oncology PC-Mishawaka | Mishawaka | Indiana | 46545 | — |
| Saint Joseph Regional Medical Center-Mishawaka | Mishawaka | Indiana | 46545 | — |
| Michiana Hematology Oncology PC-Plymouth | Plymouth | Indiana | 46563 | — |
| Memorial Hospital of South Bend | South Bend | Indiana | 46601 | — |
| Michiana Hematology Oncology PC-South Bend | South Bend | Indiana | 46601 | — |
| Northern Indiana Cancer Research Consortium | South Bend | Indiana | 46628 | — |
| Michiana Hematology Oncology PC-Westville | Westville | Indiana | 46391 | — |
| University of Iowa Healthcare Cancer Services Quad Cities | Bettendorf | Iowa | 52722 | — |
| University of Iowa/Holden Comprehensive Cancer Center | Iowa City | Iowa | 52242 | — |
| Iowa City VA Healthcare System | Iowa City | Iowa | 52246 | — |
| Harold Alfond Center for Cancer Care | Augusta | Maine | 04330 | — |
| Eastern Maine Medical Center | Bangor | Maine | 04401 | — |
| Union Hospital of Cecil County | Elkton | Maryland | 21921 | — |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| Dana-Farber/Brigham and Women's Cancer Center at Milford Regional | Milford | Massachusetts | 01757 | — |
| Newton-Wellesley Hospital | Newton | Massachusetts | 02462 | — |
| Lakeland Community Hospital | Niles | Michigan | 49120 | — |
| Lakeland Hospital | Saint Joseph | Michigan | 49085 | — |
| Marie Yeager Cancer Center | Saint Joseph | Michigan | 49085 | — |
| University of Minnesota/Masonic Cancer Center | Minneapolis | Minnesota | 55455 | — |
| University of Missouri - Ellis Fischel | Columbia | Missouri | 65212 | — |
| Capital Region Medical Center-Goldschmidt Cancer Center | Jefferson City | Missouri | 65109 | — |
| Missouri Baptist Medical Center | St Louis | Missouri | 63131 | — |
| Center for Cancer Care and Research | St Louis | Missouri | 63141 | — |
| Comprehensive Cancer Care PC | St Louis | Missouri | 63141 | — |
| CHI Health Saint Francis | Grand Island | Nebraska | 68803 | — |
| Nebraska Cancer Research Center | Lincoln | Nebraska | 68510 | — |
| Great Plains Regional Medical Center | North Platte | Nebraska | 69103 | — |
| Nebraska Methodist Hospital | Omaha | Nebraska | 68114 | — |
| Alegent Health Immanuel Medical Center | Omaha | Nebraska | 68122 | — |
| Alegent Health Bergan Mercy Medical Center | Omaha | Nebraska | 68124 | — |
| Creighton University Medical Center | Omaha | Nebraska | 68131 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| University Medical Center of Southern Nevada | Las Vegas | Nevada | 89102 | — |
| Nevada Cancer Research Foundation CCOP | Las Vegas | Nevada | 89106 | — |
| Exeter Hospital | Exeter | New Hampshire | 03833 | — |
| LRGHealthcare-Lakes Region General Hospital | Laconia | New Hampshire | 03246 | — |
| Cooper Hospital University Medical Center | Camden | New Jersey | 08103 | — |
| Hematology Oncology Associates of Central New York-East Syracuse | East Syracuse | New York | 13057 | — |
| Glens Falls Hospital | Glens Falls | New York | 12801 | — |
| North Shore University Hospital | Manhasset | New York | 11030 | — |
| Long Island Jewish Medical Center | New Hyde Park | New York | 11040 | — |
| Northwell Health/Center for Advanced Medicine | New Hyde Park | New York | 11040 | — |
| State University of New York Upstate Medical University | Syracuse | New York | 13210 | — |
| Syracuse Veterans Administration Medical Center | Syracuse | New York | 13210 | — |
| Randolph Hospital | Asheboro | North Carolina | 27203 | — |
| UNC Lineberger Comprehensive Cancer Center | Chapel Hill | North Carolina | 27599 | — |
| Novant Health Presbyterian Medical Center | Charlotte | North Carolina | 28204 | — |
| Wayne Memorial Hospital | Goldsboro | North Carolina | 27534 | — |
| Cone Health Cancer Center | Greensboro | North Carolina | 27403 | — |
| Kinston Medical Specialists PA | Kinston | North Carolina | 28501 | — |
| Annie Penn Memorial Hospital | Reidsville | North Carolina | 27320 | — |
| Iredell Memorial Hospital | Statesville | North Carolina | 28677 | — |
| Marion L Shepard Cancer Center at Vidant Beaufort Hospital | Washington | North Carolina | 27889 | — |
| New Hanover Regional Medical Center/Zimmer Cancer Center | Wilmington | North Carolina | 28401 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210 | — |
| Memorial Hospital of Rhode Island | Pawtucket | Rhode Island | 02860 | — |
| Greenville Health System Cancer Institute-Easley | Easley | South Carolina | 29640 | — |
| McLeod Regional Medical Center | Florence | South Carolina | 29506 | — |
| Saint Francis Hospital | Greenville | South Carolina | 29601 | — |
| Greenville Health System Cancer Institute-Andrews | Greenville | South Carolina | 29605 | — |
| Greenville Health System Cancer Institute-Butternut | Greenville | South Carolina | 29605 | — |
| Greenville Health System Cancer Institute-Faris | Greenville | South Carolina | 29605 | — |
| Greenville Memorial Hospital | Greenville | South Carolina | 29605 | — |
| Greenville Health System Cancer Institute-Eastside | Greenville | South Carolina | 29615 | — |
| Self Regional Healthcare | Greenwood | South Carolina | 29646 | — |
| Greenville Health System Cancer Institute-Greer | Greer | South Carolina | 29650 | — |
| Greenville Health System Cancer Institute-Seneca | Seneca | South Carolina | 29672 | — |
| Greenville Health System Cancer Institute-Spartanburg | Spartanburg | South Carolina | 29307 | — |
| Central Vermont Medical Center/National Life Cancer Treatment | Berlin Corners | Vermont | 05602 | — |
| University of Vermont College of Medicine | Burlington | Vermont | 05405 | — |
| Danville Regional Medical Center | Danville | Virginia | 24541 | — |
| Memorial Hospital Of Martinsville | Martinsville | Virginia | 24115 | — |
| Saint Mary's Medical Center | Huntington | West Virginia | 25702 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00698815, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 8, 2022 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00698815 live on ClinicalTrials.gov.