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Completed Phase 3 Interventional Results available

Safety Study Extension of Iloprost Power 15 in Pulmonary Arterial Hypertension

ClinicalTrials.gov ID: NCT00709098

Public ClinicalTrials.gov record NCT00709098. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 7:26 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Double-blind, Randomized Study Comparing the Safety and Tolerability of Iloprost Inhalation Solution Delivered by I-neb Utilizing Power Disc-15 and Power Disc-6 in Patients With Symptomatic Pulmonary Arterial Hypertension

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Patients with symptomatic idiopathic (IPAH) or familial (FPAH) pulmonary arterial hypertension in New York Heart Association (NYHA) class II to IV , naive to PAH treatment or currently being treated with a stable dose of either bosentan or sildenafil and who complete PROWESS 15 will be enrolled in the PROWESS 15 Extension study. This is a double-blind (12 week), randomized study to compare the safety and tolerability of inhaled iloprost power disc-15 and power disc-6 in patients with symptomatic pulmonary arterial hypertension (PAH). After completion of the double blind period, patients will be entered in the open label period using iloprost power disc-15.

Study identification

NCT ID
NCT00709098
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Actelion
Industry
Enrollment
49 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 31, 2008
Primary completion
May 31, 2010
Completion
May 31, 2010
Last update posted
Sep 27, 2015

2008 – 2010

United States locations

U.S. sites
32
U.S. states
22
U.S. cities
31
Facility City State ZIP Site status
UCSD Medical Center La Jolla California 92037
UC Davis Medical Center Sacramento California 95817
Liu Center for Pulmonary Hypertension - LA Biomedical Research Institute at Harbor-UCLA Torrance California 90502
Lung Health & Sleep Enhancement Center, LLC Newark Delaware 19713
University of Florida Gainesville Florida 32610
Pulmonary & Critical Care of Atlanta Atlanta Georgia 30342
Atlanta Institute for Medical Research Decatur Georgia 30033
University of Iowa Hospitals and Clinics Iowa City Iowa 52242
Mercy Hospital Iowa City Iowa 52245
Kentuckiana Pulmonary Associates Louisville Kentucky 40202
LSU Health Sciences Center New Orleans Louisiana 70112
University of Maryland Medical Center Baltimore Maryland 21201
University of Nebraska Medical Center Omaha Nebraska 68198
Newark Beth Israel Medical Center Newark New Jersey 07112
Winthrop University Hospital Mineola New York 11501
University of North Carolina Chapel Hill North Carolina 27599-7020
The Lindner Clinical Trial Center Cincinnati Ohio 45219
The Ohio State University Medical Center Columbus Ohio 43221
Legacy Health System Portland Oregon 97210
Temple University Hospital Philadelphia Pennsylvania 19140
Allegheny General Hospital Pittsburgh Pennsylvania 15212
Rhode Island Hospital Providence Rhode Island 02903
Lexington Pulmonary & Critical Care Lexington South Carolina 29072
UT Southwestern Medical Center Heart Lung and Vacular Center Dallas Texas 75390-8550
University of Texas Medical School Houston Texas 77030
Central Utah Clinic, P.C. American Fork Utah 84003
Intermountain Medical Center Murray Utah 84157
University of Virginia Charlottesville Virginia 22908
Sentara Hospitals T/A Sentara Cardiovascular Research Institute Norfolk Virginia 23507
Spokane Respiratory Consultants Spokane Washington 99204
UW Hospital & Clinics Madison Wisconsin 53792
Comprehensive Cardiovascular Care LLP Milwaukee Wisconsin 53215

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00709098, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 27, 2015 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00709098 live on ClinicalTrials.gov.

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