Safety and Efficacy of Gadobutrol 1.0 Molar (Gadavist) in Patients for Central Nervous System (CNS) Imaging
Public ClinicalTrials.gov record NCT00709852. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-blind, Crossover, Phase 3 Study to Determine the Safety and Efficacy of Gadobutrol 1.0 Molar (Gadavist) in Patients Referred for Contrast-enhanced MRI of the Central Nervous System (CNS)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study involves the use of Magnetic Resonance Imaging (MRI) contrast agents called gadobutrol (Gadavist) Injection and ProHance Injection. The purpose of this study is to look at the safety (what are the side effects) and efficacy (how well does it work) of gadobutrol when used for taking MR images of the brain and spine. The results of the MRI with gadobutrol Injection will be compared to the results of MR images taken without contrast and with the results of the MR images taken with ProHance.
Study identification
- NCT ID
- NCT00709852
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 402 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2008 (Type not available)
- Primary completion
- Apr 2009 (Actual)
- Completion
- Apr 2009 (Actual)
- Last update posted
- Dec 30, 2014
2008 – 2009
United States locations
- U.S. sites
- 24
- U.S. states
- 17
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| West Alabama Research, Inc. | Birmingham | Alabama | 35209 | — |
| Achieve Clinical Research, LLC | Tuscaloosa | Alabama | 35406 | — |
| Los Gatos MRI | Los Gatos | California | 95032 | — |
| Hoag Memorial Hospital Presbyterian | Newport Beach | California | 92658-6100 | — |
| Redwood Regional Medical Group, Inc. | Santa Rosa | California | 95403 | — |
| University of Florida - Jacksonville | Jacksonville | Florida | 32209 | — |
| NorthShore University HealthSystem-Evanston Hospital | Evanston | Illinois | 60201 | — |
| Atchison Hospital | Atchison | Kansas | 66002 | — |
| University of Maryland Hospital System | Baltimore | Maryland | 21201 | — |
| Johns Hopkins Hospital/Health System | Baltimore | Maryland | 21287 | — |
| Shields MRI - Brockton | Brockton | Massachusetts | 02301 | — |
| VA Boston Healthcare System-West Roxbury Division | West Roxbury | Massachusetts | 02132 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| University of New Mexico School of Medicine | Albuquerque | New Mexico | 87131 | — |
| Kingston Neurological Associates, PC | Kingston | New York | 12401 | — |
| NYU Hospital for Joint Diseases | New York | New York | 10003 | — |
| Duke University Medical Center | Durham | North Carolina | 27707 | — |
| The Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
| Aurora Saint Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 55 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00709852, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 30, 2014 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00709852 live on ClinicalTrials.gov.