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Completed Phase 3 Interventional

Study to Assess the Safety and Tolerability of IV Tonapofylline in Subjects With Acute Decompensated Heart Failure (ADHF) and Renal Insufficiency

ClinicalTrials.gov ID: NCT00709865

Public ClinicalTrials.gov record NCT00709865. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 11, 2026, 12:18 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Assess the Safety and Tolerability of Intravenous Tonapofylline in Subjects With Acute Decompensated Heart Failure and Renal Insufficiency

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of the current study is to assess the safety and tolerability of intravenous tonapofylline.

Study identification

NCT ID
NCT00709865
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Biogen
Industry
Enrollment
420 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 30, 2008
Primary completion
Oct 29, 2009
Completion
Dec 30, 2009
Last update posted
Sep 10, 2023

2008 – 2009

United States locations

U.S. sites
68
U.S. states
29
U.S. cities
67
Facility City State ZIP Site status
Not listed Huntsville Alabama 35801
Not listed Mobile Alabama 36608
Not listed Fort Smith Arkansas 72917
Not listed Beverly Hills California 90210
Not listed Chula Vista California 91911
Not listed Mission Viejo California 92691
Not listed Monterey Park California 91754
Not listed Oceanside California 92056
Not listed Redondo Beach California 90277
Not listed San Diego California 92103
Not listed Sylmar California 91342
Not listed Torrance California 90502
Not listed Yuba City California 95991
Not listed Hartford Connecticut 06102
Not listed Jacksonville Florida 32216
Not listed Sarasota Florida 34239
Not listed Tampa Florida 33613
Not listed Lombard Illinois 60148
Not listed Indianapolis Indiana 46202
Not listed Muncie Indiana 47303
Not listed Iowa City Iowa 52242
Not listed Kansas City Kansas 64132
Not listed Wichita Kansas 67220
Not listed Baltimore Maryland 21201
Not listed Ayer Massachusetts 01432
Not listed Boston Massachusetts 02114
Not listed Hyannis Massachusetts 02601
Not listed Springfield Massachusetts 01107
Not listed West Springfield Massachusetts 01089
Not listed Traverse City Michigan 49684
Not listed Minneapolis Minnesota 55404
Not listed Kansas City Missouri 64132
Not listed Lee's Summit Missouri 64063
Not listed St Louis Missouri 63128
Not listed Omaha Nebraska 68131
Not listed Ridgewood New Jersey 07450
Not listed Johnson City New York 13790
Not listed Mineola New York 11501
Not listed New York New York 10021
Not listed Stony Brook New York 11794
Not listed The Bronx New York 10461
Not listed Concord North Carolina 28025
Not listed Cincinnati Ohio 45267
Not listed Cleveland Ohio 44195
Not listed Columbus Ohio 43210
Not listed Franklin Ohio 45005
Not listed Oklahoma City Oklahoma 73109
Not listed Oklahoma City Oklahoma 73120
Not listed Tulsa Oklahoma 74104
Not listed Portland Oregon 97213
Not listed Camp Hill Pennsylvania 17011
Not listed Danville Pennsylvania 17822
Not listed Doylestown Pennsylvania 18901
Not listed Lancaster Pennsylvania 17603
Not listed Philadelphia Pennsylvania 19140
Not listed Providence Rhode Island 02908
Not listed Orangeburg South Carolina 29118
Not listed Nashville Tennessee 37208
Not listed Oak Ridge Tennessee 37830
Not listed Tullahoma Tennessee 37388
Not listed Dallas Texas 75216
Not listed Houston Texas 77030
Not listed San Antonio Texas 78215
Not listed Whitney Texas 76692
Not listed Danville Virginia 24541
Not listed Olympia Washington 98506
Not listed Tacoma Washington 98405
Not listed Charleston West Virginia 25304

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 121 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00709865, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 10, 2023 · Synced Sep 11, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00709865 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →