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Completed Phase 2 Interventional Results available

A Study of SB-742457, Added to Donepezil for the Treatment of Mild-to-moderate Alzheimer's Disease

ClinicalTrials.gov ID: NCT00710684

Public ClinicalTrials.gov record NCT00710684. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 5:27 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Study AZ3110866, a Fixed Dose Study of SB-742457 Versus Placebo When Added to Existing Donepezil Treatment in Subjects With Mild-to-moderate Alzheimer's Disease

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The study is designed to investigate the safety and efficacy of SB-742457 when added to stable donepezil treatment in subjects with mild-to-moderate Alzheimer's disease.

Study identification

NCT ID
NCT00710684
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
GlaxoSmithKline
Industry
Enrollment
682 participants

Conditions and interventions

Eligibility (public fields only)

Age range
50 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 1, 2008 (Actual)
Primary completion
May 21, 2010 (Actual)
Completion
Nov 16, 2010 (Actual)
Last update posted
Dec 7, 2017

2008 – 2010

United States locations

U.S. sites
14
U.S. states
11
U.S. cities
14
Facility City State ZIP Site status
GSK Investigational Site Litchfield Park Arizona 85340 —
GSK Investigational Site Fresno California 93720 —
GSK Investigational Site Rancho Mirage California 92270 —
GSK Investigational Site San Francisco California 94109 —
GSK Investigational Site Hallandale Florida 33009 —
GSK Investigational Site Hialeah Florida 33016 —
GSK Investigational Site Paterson New Jersey 08759 —
GSK Investigational Site Syracuse New York 13210 —
GSK Investigational Site Winston-Salem North Carolina 27103 —
GSK Investigational Site Columbus Ohio 43210 —
GSK Investigational Site Tulsa Oklahoma 74104 —
GSK Investigational Site Memphis Tennessee 38119 —
GSK Investigational Site Austin Texas 78757 —
GSK Investigational Site Bennington Vermont 05201 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 88 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00710684, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 7, 2017 · Synced Oct 19, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00710684 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →