Safety and Efficacy Study of Aztreonam for Inhalation Solution (AZLI) in Patients With Cystic Fibrosis, Mild Lung Disease, and P. Aeruginosa
Public ClinicalTrials.gov record NCT00712166. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-Blind, Multicenter, Multinational, Randomized, Placebo-Controlled Trial Evaluating Aztreonam Lysine For Inhalation in Patients With Cystic Fibrosis, Mild Lung Disease, and P. Aeruginosa (AIR-CF4)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study was to evaluate the safety and efficacy of a 28-day course of aztreonam for inhalation solution (AZLI) in patients with cystic fibrosis (CF), mild lung disease (forced expiratory volume in 1 second \[FEV1\] \>75% predicted, and Pseudomonas aeruginosa (PA) infection.
Study identification
- NCT ID
- NCT00712166
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 160 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 6 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2008 (Type not available)
- Primary completion
- Jun 2009 (Actual)
- Completion
- Aug 2009 (Actual)
- Last update posted
- Dec 20, 2010
2008 – 2009
United States locations
- U.S. sites
- 34
- U.S. states
- 19
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Phoenix Children's Hospital | Phoenix | Arizona | — | — |
| University Medical Center | Tucson | Arizona | — | — |
| Arkansas Children's Hospital | Little Rock | Arkansas | — | — |
| University of Arkansas for Medical Sciences, Division of Pulmonary and Critical Care Medicine | Little Rock | Arkansas | — | — |
| Kaiser Permanente | Oakland | California | — | — |
| Children's Hospital of Orange County | Orange | California | — | — |
| The Children's Hospital | Aurora | Colorado | — | — |
| Connecticut Children's Medical Center | Hartford | Connecticut | — | — |
| Nemours Children's Clinic | Jacksonville | Florida | — | — |
| Nemours Children's Clinic | Orlando | Florida | — | — |
| Children's Memorial Hospital | Chicago | Illinois | — | — |
| Indiana University, Outpatient Clinical Research Facility | Indianapolis | Indiana | — | — |
| James Whitcomb Riley Hospital for Children | Indianapolis | Indiana | — | — |
| Children's Hospital, Boston | Boston | Massachusetts | — | — |
| Tufts Medical Center, Pediatric Pulmonary Clinic | Boston | Massachusetts | — | — |
| University of Michigan Health System | Ann Arbor | Michigan | — | — |
| The Children's Hospital of Michigan, Detroit Medical Center | Detroit | Michigan | — | — |
| The Minnesota CF Center, University of Minnesota Medical Center | Minneapolis | Minnesota | — | — |
| Children's Lung Specialists | Las Vegas | Nevada | — | — |
| Albany Medical College | Albany | New York | — | — |
| The Lung & Cystic Fibrosis Center, University of Buffalo Pediatric Associates, Inc., Women & Children's Hospital of Buffalo | Buffalo | New York | — | — |
| Long Island Jewish Medical Center | New Hyde Park | New York | — | — |
| SUNY Upstate Medical University | Syracuse | New York | — | — |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | — | — |
| Nationwide Children's Hospital | Columbus | Ohio | — | — |
| Toledo Children's Hospital/Toledo Hospital, Cystic Fibrosis Research Center | Toledo | Ohio | — | — |
| Santiago Reyes, MD | Oklahoma City | Oklahoma | — | — |
| Penn State Milton S. Hershey Medical Center | Hershey | Pennsylvania | — | — |
| Drexel University College of Medicine, Pulmonary Associates | Philadelphia | Pennsylvania | — | — |
| Penn Presbyterian Medical Center | Philadelphia | Pennsylvania | — | — |
| St. Christopher's Hospital for Children | Philadelphia | Pennsylvania | — | — |
| Baylor College of Medicine | Houston | Texas | — | — |
| Primary Children's Medical Center | Salt Lake City | Utah | — | — |
| Children's Hospital and Regional Medical Center | Seattle | Washington | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00712166, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 20, 2010 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00712166 live on ClinicalTrials.gov.