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Terminated Phase 1 Interventional

A Phase 1 Dose Escalation Study of IPI-493

ClinicalTrials.gov ID: NCT00724425

Public ClinicalTrials.gov record NCT00724425. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 5, 2026, 10:23 AM EST

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Official title

A Phase 1 Dose Escalation Study of the Safety and Pharmacokinetics of IPI-493 Orally Administered to Patients With Advanced Malignancies

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

IPI-493 is a potent inhibitor of heat shock protein 90 (Hsp90) and is orally bioavailable via a novel formulation.

Study identification

NCT ID
NCT00724425
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
Infinity Pharmaceuticals, Inc.
Industry
Enrollment
53 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 2008 (Type not available)
Primary completion
Jul 2011 (Actual)
Completion
Jul 2011 (Actual)
Last update posted
Apr 15, 2015

2008 – 2011

United States locations

U.S. sites
5
U.S. states
4
U.S. cities
5
Facility City State ZIP Site status
Premiere Oncology, Arizona Scottsdale Arizona 85260 —
San Diego Pacific Oncology and Hematology Associates Encinitas California 92024 —
Premiere Oncology, California Santa Monica California 90404 —
Univeristy of Colorado Health Science Center Aurora Colorado 80045 —
Mary Crowley Cancer Research Center Dallas Texas 75201 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00724425, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 15, 2015 · Synced Nov 5, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00724425 live on ClinicalTrials.gov.

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