Oral Cladribine in Early Multiple Sclerosis (MS)
Public ClinicalTrials.gov record NCT00725985. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Randomized, Double-blind, Placebo-controlled, Multi-center Clinical Trial of Oral Cladribine in Subjects With a First Clinical Event at High Risk of Converting to MS
Study identification
- NCT ID
- NCT00725985
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- EMD Serono Research & Development Institute, Inc.
- Industry
- Enrollment
- 617 participants
Conditions and interventions
Conditions
Interventions
- Cladribine Drug
- Placebo Drug
- Rebif® new formulation (RNF) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 55 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 30, 2008
- Primary completion
- Jul 30, 2011
- Completion
- Apr 29, 2012
- Last update posted
- Mar 21, 2021
2008 – 2012
United States locations
- U.S. sites
- 24
- U.S. states
- 17
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Hope Research Institute Medical Plaza LLC Desert Hills | Phoenix | Arizona | — | — |
| Multiple Sclerosis Center Drive, Neurology Suite 701 | Newport Beach | California | — | — |
| University of Colorado at Denver Health Sciences | Denver | Colorado | — | — |
| Fort Collins Neurology | Fort Collins | Colorado | — | — |
| MS Center of Brevard MIMA Centry Research Associates | Melbourne | Florida | — | — |
| University of South Florida | Tampa | Florida | — | — |
| MS Center of Atlanta | Atlanta | Georgia | — | — |
| Bruce Hughes West Building | Des Moines | Iowa | — | — |
| Michigan Neurology Associates | Clinton Township | Michigan | — | — |
| Henry Ford Hospital | Detroit | Michigan | — | — |
| University of Minnesota | Minneapolis | Minnesota | — | — |
| Dennis Dietrich | Great Falls | Montana | — | — |
| University of Medicine and Dentistry of New Jersey School of Neurology | Stratford | New Jersey | — | — |
| Upstate Clinical Research LLC 3 | Albany | New York | — | — |
| Neurological Specialists of Long Island | Great Neck | New York | — | — |
| Multiple Sclerosis Center of Northeastern NY | New York | New York | — | — |
| Comprehensive MS Care Clinic at South Shore Multiple Sclerosis | Patchogue | New York | — | — |
| Carolinas Medical Center | Charlotte | North Carolina | — | — |
| Meritcare Neuroscience Center Neurology | Fargo | North Dakota | — | — |
| University of Cincinnati | Cincinnati | Ohio | — | — |
| MS Center of Oklahoma | Oklahoma City | Oklahoma | — | — |
| Neurology and Sleep Medicine | Bethlehem | Pennsylvania | — | — |
| Swedish Medical Center Cherry Hill | Seattle | Washington | — | — |
| Neurology & Neurological Association of Tacoma | Tacoma | Washington | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 134 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00725985, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 21, 2021 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00725985 live on ClinicalTrials.gov.