Independent directory Public ClinicalTrials.gov records United States
ClinicalTrials.gov record
Terminated Phase 2 Interventional Results available

Sorafenib, Cisplatin, and Etoposide in Treating Patients With Extensive-Stage Small Cell Lung Cancer

ClinicalTrials.gov ID: NCT00726986

Public ClinicalTrials.gov record NCT00726986. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 30, 2026, 11:34 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase II Trial of Sorafenib in Conjunction With Chemotherapy and as Maintenance Therapy in Extensive-Stage Small Cell Lung Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Sorafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Drugs used in chemotherapy, such as cisplatin and etoposide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving sorafenib together with combination chemotherapy may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving sorafenib together with cisplatin and etoposide works in treating patients with extensive-stage small cell lung cancer.

Study identification

NCT ID
NCT00726986
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Afshin Dowlati, MD
Other
Enrollment
18 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 2008 (Type not available)
Primary completion
Jul 2012 (Actual)
Completion
Jul 2012 (Actual)
Last update posted
Nov 19, 2014

2008 – 2012

United States locations

U.S. sites
11
U.S. states
2
U.S. cities
4
Facility City State ZIP Site status
Columbia Presbyterian New York New York 10032 —
Lake/University Ireland Cancer Center Cleveland Ohio 44060 —
Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center Cleveland Ohio 44106-5065 —
MetroHealth Medical Center Cleveland Ohio 44109 —
CCF-Fairview Hospital Cleveland Ohio 44111 —
UHHS Chagrin Highlands Medical Center Cleveland Ohio 44122 —
Southwest General Health Center Cleveland Ohio 44130 —
UHHS Westlake Medical Center Cleveland Ohio 44145 —
Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center Cleveland Ohio 44195 —
UH-Monarch Mayfield Heights Ohio 44124 —
UH-Firelands Sandusky Ohio 44870 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00726986, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 19, 2014 · Synced Sep 30, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00726986 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →