Efficacy and Safety of Pioglitazone and Metformin Combination Therapy in Treating Type 2 Diabetes Mellitus.
Public ClinicalTrials.gov record NCT00727857. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3b, Double-Blind, Randomized Study to Determine the Efficacy and Safety of Pioglitazone HCl and Metformin HCl Fixed-Dose Combination Therapy Compared to Pioglitazone HCl Monotherapy and to Metformin HCl Monotherapy in the Treatment of Subjects With Type 2 Diabetes
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the efficacy of pioglitazone, twice daily (BID), combined with metformin versus pioglitazone taken alone and metformin taken alone in treating Type 2 Diabetes Mellitus.
Study identification
- NCT ID
- NCT00727857
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 600 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2007 (Type not available)
- Primary completion
- Aug 2008 (Actual)
- Completion
- Aug 2008 (Actual)
- Last update posted
- Jul 29, 2011
2007 – 2008
United States locations
- U.S. sites
- 66
- U.S. states
- 27
- U.S. cities
- 66
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Birmingham | Alabama | — | — |
| Not listed | Haleyville | Alabama | — | — |
| Not listed | Montgomery | Alabama | — | — |
| Not listed | Pell City | Alabama | — | — |
| Not listed | Phoenix | Arizona | — | — |
| Not listed | Tucson | Arizona | — | — |
| Not listed | Anaheim | California | — | — |
| Not listed | Artesia | California | — | — |
| Not listed | Dinuba | California | — | — |
| Not listed | Long Beach | California | — | — |
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| Not listed | Norwalk | California | — | — |
| Not listed | Orange | California | — | — |
| Not listed | Santa Ana | California | — | — |
| Not listed | Santa Monica | California | — | — |
| Not listed | Pueblo | Colorado | — | — |
| Not listed | Altamonte Springs | Florida | — | — |
| Not listed | Coral Gables | Florida | — | — |
| Not listed | Hialeah | Florida | — | — |
| Not listed | Miami | Florida | — | — |
| Not listed | Panama City | Florida | — | — |
| Not listed | Plantation | Florida | — | — |
| Not listed | Saint Cloud | Florida | — | — |
| Not listed | St. Petersburg | Florida | — | — |
| Not listed | Tampa | Florida | — | — |
| Not listed | Columbus | Georgia | — | — |
| Not listed | Boise | Idaho | — | — |
| Not listed | Coeur d'Alene | Idaho | — | — |
| Not listed | Chicago | Illinois | — | — |
| Not listed | Flossmoor | Illinois | — | — |
| Not listed | Peoria | Illinois | — | — |
| Not listed | Elkhart | Indiana | — | — |
| Not listed | Shawnee | Kansas | — | — |
| Not listed | Southfield | Michigan | — | — |
| Not listed | Chesterfield | Missouri | — | — |
| Not listed | Billings | Montana | — | — |
| Not listed | Elizabeth | New Jersey | — | — |
| Not listed | Fayetteville | New York | — | — |
| Not listed | New York | New York | — | — |
| Not listed | Durham | North Carolina | — | — |
| Not listed | Pinehurst | North Carolina | — | — |
| Not listed | Cincinnati | Ohio | — | — |
| Not listed | Perrysburg | Ohio | — | — |
| Not listed | Zanesville | Ohio | — | — |
| Not listed | Oklahoma City | Oklahoma | — | — |
| Not listed | Eugene | Oregon | — | — |
| Not listed | Fleetwood | Pennsylvania | — | — |
| Not listed | Norristown | Pennsylvania | — | — |
| Not listed | Cranston | Rhode Island | — | — |
| Not listed | Simpsonville | South Carolina | — | — |
| Not listed | Varnville | South Carolina | — | — |
| Not listed | Fayetteville | Tennessee | — | — |
| Not listed | Corpus Christi | Texas | — | — |
| Not listed | Dallas | Texas | — | — |
| Not listed | El Paso | Texas | — | — |
| Not listed | Houston | Texas | — | — |
| Not listed | McAllen | Texas | — | — |
| Not listed | Mission | Texas | — | — |
| Not listed | New Braunfels | Texas | — | — |
| Not listed | North Richland Hills | Texas | — | — |
| Not listed | San Antonio | Texas | — | — |
| Not listed | Bountiful | Utah | — | — |
| Not listed | Salt Lake City | Utah | — | — |
| Not listed | Petersburg | Virginia | — | — |
| Not listed | Port Orchard | Washington | — | — |
| Not listed | Spokane | Washington | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00727857, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 29, 2011 · Synced Oct 28, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00727857 live on ClinicalTrials.gov.