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Completed Phase 3 Interventional

Efficacy and Safety of Fixed Combination Therapy of Vildagliptin and Metformin (25/1000 mg Bid) in Patients With Type 2 Diabetes Inadequately Controlled With Prior Metformin Monotherapy (HbA1c 7.0-9.5%)

ClinicalTrials.gov ID: NCT00728351

Public ClinicalTrials.gov record NCT00728351. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 24, 2026, 9:22 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Double-blind, Randomized Study to Compare the Efficacy of 24 Weeks Treatment With Fixed Combination Therapy of Vildagliptin and Metformin (25/1000 mg Bid) Versus Metformin Monotherapy (1000 mg Bid) in Patients With Type 2 Diabetes Inadequately Controlled With Metformin Monotherapy.

Study identification

NCT ID
NCT00728351
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
317 participants

Conditions and interventions

Interventions

  • vildagliptin + metformin Drug
  • metformin Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 78 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 31, 2008
Primary completion
Jan 31, 2010
Completion
Not listed
Last update posted
Dec 18, 2020

Started 2008

United States locations

U.S. sites
16
U.S. states
13
U.S. cities
14
Facility City State ZIP Site status
Not listed Pine Bluff Arkansas 71603
Not listed Long Beach California 90806
Not listed Denver Colorado 80209
Not listed Bangor Maine 04401
Not listed Billings Montana 59102
Novartis Investigative Site New Brunswick New Jersey 08903
Not listed Trenton New Jersey 08611
Not listed Wilmington North Carolina 28409
Not listed Oklahoma City Oklahoma 73104
Not listed Uniontown Pennsylvania
Not listed Taylors South Carolina 29687
Not listed Houston Texas 77023
Not listed Houston Texas 77074
Not listed Houston Texas 77081
Not listed Norfolk Virginia 23510
Not listed Wenatchee Washington 98801

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 47 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00728351, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 18, 2020 · Synced Jul 24, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00728351 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →