ClinicalTrials.gov record
Trial of Linaclotide in Patients With Chronic Constipation
ClinicalTrials.gov ID: NCT00730015
Public ClinicalTrials.gov record NCT00730015. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel-group Trial of Linaclotide Administered Orally for 12 Weeks Followed by a 4-Week Randomized Withdrawal Period in Patients With Chronic Constipation
Study identification
- NCT ID
- NCT00730015
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Ironwood Pharmaceuticals, Inc.
- Industry
- Enrollment
- 643 participants
Conditions and interventions
Conditions
Interventions
- Matching Placebo Drug
- Linaclotide Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 31, 2008
- Primary completion
- Jul 31, 2009
- Completion
- Sep 30, 2009
- Last update posted
- Jan 29, 2013
2008 – 2009
United States locations
- U.S. sites
- 105
- U.S. states
- 32
- U.S. cities
- 101
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Ironwood Investigational Site | Birmingham | Alabama | 35209 | — |
| Ironwood Investigational Site | Huntsville | Alabama | 35801 | — |
| Ironwood Investigational Site | Chandler | Arizona | 85224 | — |
| Ironwood Investigational Site | Phoenix | Arizona | 85020 | — |
| Ironwood Investigational Site | Tucson | Arizona | 85715 | — |
| Ironwood Investigational Site | Tuscon | Arizona | 85710 | — |
| Ironwood Investigational Site | Sherwood | Arkansas | 72120 | — |
| Ironwood Investigational Site | Anaheim | California | 92801 | — |
| Ironwood Investigational Site | Chula Vista | California | 91910 | — |
| Ironwood Investigational Site | Encinitas | California | 92024 | — |
| Ironwood Investigational Site | Garden Grove | California | 92840 | — |
| Ironwood Investigational Site | Laguna Hills | California | 92653 | — |
| Ironwood Investigational Site | Los Angeles | California | 90045 | — |
| Ironwood Investigational Site | Orange | California | 92868 | — |
| Ironwood Investigational Site | Sacramento | California | 95830 | — |
| Ironwood Investigational Site | San Carlos | California | 94070 | — |
| Ironwood Investigational Site | San Diego | California | 92103 | — |
| Ironwood Investigational Site | San Diego | California | 92108 | — |
| Ironwood Investigational Site | San Diego | California | 92123 | — |
| Ironwood Investigational Site | Colorado Springs | Colorado | 80904 | — |
| Ironwood Investigational Site | Bristol | Connecticut | 06010 | — |
| Ironwood Investigational Site | Boynton Beach | Florida | 33426 | — |
| Ironwood Investigational Site | Hollywood | Florida | 33021 | — |
| Ironwood Investigational Site | Inverness | Florida | 34452 | — |
| Ironwood Investigational Site | Jacksonville | Florida | 32256 | — |
| Ironwood Investigational Site | Port Orange | Florida | 32129 | — |
| Ironwood Investigational Site | Tampa | Florida | 33607 | — |
| Ironwood Investigational Site | Newnan | Georgia | 30263 | — |
| Ironwood Investigational Site | Peoria | Illinois | 61602 | — |
| Ironwood Investigational Site | Anderson | Indiana | 46011 | — |
| Ironwood Investigational Site | Clive | Iowa | 50325 | — |
| Ironwood Investigational Site | Davenport | Iowa | 52807 | — |
| Ironwood Investigational Site | Mission | Kansas | 66202 | — |
| Ironwood Investigational Site | Overland Park | Kansas | 66215 | — |
| Ironwood Investigational Site | Topeka | Kansas | 66606 | — |
| Ironwood Investigational Site | Baton Rouge | Louisiana | 70809 | — |
| Ironwood Investigational Site | Monroe | Louisiana | 71201 | — |
| Ironwood Investigational Site | Shreveport | Louisiana | 71103 | — |
| Ironwood Investigational Site | Annapolis | Maryland | 21401 | — |
| Ironwood Investigational Site | Baltimore | Maryland | 21215 | — |
| Ironwood Investigational Site | Hollywood | Maryland | 20636 | — |
| Ironwood Investigational Site | Laurel | Maryland | 20707 | — |
| Ironwood Investigational Site | Chesterfield | Michigan | 48047 | — |
| Ironwood Investigational Site | Traverse City | Michigan | 49684 | — |
| Ironwood Investigational Site | Troy | Michigan | 48098 | — |
| Ironwood Investigational Site | Jackson | Mississippi | 39202 | — |
| Ironwood Investigational Site | Tupelo | Mississippi | 38801 | — |
| Ironwood Investigational Site | Jefferson City | Missouri | 65109 | — |
| Ironwood Investigational Site | Henderson | Nevada | 89104 | — |
| Ironwood Investigational Site | Las Vegas | Nevada | 89128 | — |
| Ironwood Investigational Site | Cedar Knolls | New Jersey | 07927 | — |
| Ironwood Investigational Site | Marlton | New Jersey | 08053 | — |
| Ironwood Investigational Site | Ocean City | New Jersey | 07712 | — |
| Ironwood Investigational Site | Albuquerque | New Mexico | 87108 | — |
| Ironwood Investigational Site | Mineola | New York | 11501 | — |
| Ironwood Investigational Site | Pittsford | New York | 14534 | — |
| Ironwood Investigational Site | Asheboro | North Carolina | 27203 | — |
| Ironwood Investigational Site | Asheville | North Carolina | 28801 | — |
| Ironwood Investigational Site | Chapel Hill | North Carolina | 27599 | — |
| Ironwood Investigational Site | Charlotte | North Carolina | 28211 | — |
| Ironwood Investigational Site | Greensboro | North Carolina | 27408 | — |
| Ironwood Investigational Site | Harrisburg | North Carolina | 28075 | — |
| Ironwood Investigational Site | Hickory | North Carolina | 28602 | — |
| Ironwood Investigational Site | Jacksonville | North Carolina | 28546 | — |
| Ironwood Investigational Site | New Bern | North Carolina | 28562 | — |
| Ironwood Investigational Site | Statesville | North Carolina | 28625 | — |
| Ironwood Investigational Site | Summerville | North Carolina | 29485 | — |
| Ironwood Investigational Site | Wilmington | North Carolina | 28401 | — |
| Ironwood Investigational Site | Winston-Salem | North Carolina | 27103 | — |
| Ironwood Investigational Site | Beachwood | Ohio | 44122 | — |
| Ironwood Investigational Site | Cincinnati | Ohio | 45224 | — |
| Ironwood Investigational Site | Cincinnati | Ohio | 45242 | — |
| Ironwood Investigational Site | Dayton | Ohio | 45440 | — |
| Ironwood Investigational Site | Sylvania | Ohio | 43560 | — |
| Ironwood Investigational Site | Wadsworth | Ohio | 44281 | — |
| Ironwood Investigational Site | Zanesville | Ohio | 43701 | — |
| Ironwood Investigational Site | Oklahoma City | Oklahoma | 73116 | — |
| Ironwood Investigational Site | Yukon | Oklahoma | 73099 | — |
| Ironwood Investigational Site | Lancaster | Pennsylvania | 17604 | — |
| Ironwood Investigational Site | Lancaster | Pennsylvania | 19606 | — |
| Ironwood Investigational Site | Levittown | Pennsylvania | 19056 | — |
| Ironwood Investigational Site | Pittsburgh | Pennsylvania | 15213 | — |
| Ironwood Investigational Site | Sellersville | Pennsylvania | 18960 | — |
| Ironwood Investigational Site | Anderson | South Carolina | 29621 | — |
| Ironwood Investigational Site | Charleston | South Carolina | 29414 | — |
| Ironwood Investigational Site | Simpsonville | South Carolina | 29681 | — |
| Ironwood Investigational Site | Bristol | Tennessee | 37620 | — |
| Ironwood Investigational Site | Chattanooga | Tennessee | 37421 | — |
| Ironwood Investigational Site | Germantown | Tennessee | 38138 | — |
| Ironwood Investigational Site | Kingsport | Tennessee | 37660 | — |
| Ironwood Investigational Site | Nashville | Tennessee | 37203 | — |
| Ironwood Investigational Site | Beaumont | Texas | 77701 | — |
| Ironwood Investigational Site | El Paso | Texas | 79905 | — |
| Ironwood Investigational Site | Houston | Texas | 77024 | — |
| Ironwood Investigational Site | Irving | Texas | 75061 | — |
| Ironwood Investigational Site | Longview | Texas | 75605 | — |
| Ironwood Investigational Site | San Antonio | Texas | 78229 | — |
| Ironwood Investigational Site | Ogden | Utah | 84405 | — |
| Ironwood Investigational Site | Salt Lake City | Utah | 84107 | — |
| Ironwood Investigational Site | Chesapeake | Virginia | 23320 | — |
| Ironwood Investigational Site | Lynchburg | Virginia | 24502 | — |
| Ironwood Investigational Site | Spokane | Washington | 99208 | — |
| Ironwood Investigational Site | Vancouver | Washington | 98664 | — |
| Ironwood Investigational Site | La Crosse | Wisconsin | 54601 | — |
| Ironwood Investigational Site | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00730015, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 29, 2013 · Synced Jun 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00730015 live on ClinicalTrials.gov.