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Completed Phase 2 Interventional Results available

Prevention Study in Adult Patients Suffering From Migraine Headaches

ClinicalTrials.gov ID: NCT00742209

Public ClinicalTrials.gov record NCT00742209. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 1:07 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Study MPX111381: A Dose-ranging Study Evaluating the Efficacy, Safety and Tolerability of GSK1838262 (XP13512) in the Prophylactic Treatment of Migraine Headache

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Purpose of the study is to evaluate dose response relationship, efficacy, safety and tolerability of target doses of GSK1838262 compared to placebo in the prophylactic treatment of migraine headache. Once subjects complete the baseline and meet the randomization criteria, they will complete a 5-wk flexible titration period and then enter the 12 week maintenance period.

Study identification

NCT ID
NCT00742209
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
XenoPort, Inc.
Industry
Enrollment
526 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 2008 (Type not available)
Primary completion
Jun 2010 (Actual)
Completion
Jun 2010 (Actual)
Last update posted
Jul 22, 2013

2008 – 2010

United States locations

U.S. sites
45
U.S. states
22
U.S. cities
40
Facility City State ZIP Site status
GSK Investigational Site Birmingham Alabama 35233 —
GSK Investigational Site Phoenix Arizona 85016 —
GSK Investigational Site Phoenix Arizona 85023 —
GSK Investigational Site Anaheim California 92801 —
GSK Investigational Site Newport Beach California 92660 —
GSK Investigational Site Redlands California 92374 —
GSK Investigational Site San Francisco California 94109 —
GSK Investigational Site Santa Monica California 90404 —
GSK Investigational Site Westlake Village California 91361 —
GSK Investigational Site Colorado Springs Colorado 80904 —
GSK Investigational Site Colorado Springs Colorado 80909 —
GSK Investigational Site Denver Colorado 80239 —
GSK Investigational Site DeLand Florida 32720 —
GSK Investigational Site Sunrise Florida 33351 —
GSK Investigational Site West Palm Beach Florida 33407 —
GSK Investigational Site Atlanta Georgia 30308 —
GSK Investigational Site Stockbridge Georgia 30281 —
GSK Investigational Site Chicago Illinois 60642 —
GSK Investigational Site Wichita Kansas 67207 —
GSK Investigational Site Kalamazoo Michigan 49009 —
GSK Investigational Site Golden Valley Minnesota 55422 —
GSK Investigational Site Kansas City Missouri 64111 —
GSK Investigational Site Springfield Missouri 65807 —
GSK Investigational Site St Louis Missouri 63141 —
GSK Investigational Site Las Vegas Nevada 89119 —
GSK Investigational Site Albany New York 12206 —
GSK Investigational Site Greensboro North Carolina 27405 —
GSK Investigational Site Raleigh North Carolina 27607 —
GSK Investigational Site Raleigh North Carolina 27609 —
GSK Investigational Site Cleveland Ohio 44195 —
GSK Investigational Site West Chester Ohio 45069 —
GSK Investigational Site Westerville Ohio 43081 —
GSK Investigational Site Philadelphia Pennsylvania 19107 —
GSK Investigational Site Philadelphia Pennsylvania 19139 —
GSK Investigational Site Pittsburgh Pennsylvania 15236 —
GSK Investigational Site Charleston South Carolina 29412 —
GSK Investigational Site Memphis Tennessee 38018 —
GSK Investigational Site Nashville Tennessee 37203 —
GSK Investigational Site Houston Texas 77004 —
GSK Investigational Site San Antonio Texas 78205 —
GSK Investigational Site Salt Lake City Utah 84109 —
GSK Investigational Site Salt Lake City Utah 84121 —
GSK Investigational Site Alexandria Virginia 22311 —
GSK Investigational Site Seattle Washington 98195 —
GSK Investigational Site Wenatchee Washington 98801 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00742209, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 22, 2013 · Synced Oct 21, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00742209 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →