Safety and Efficacy Study to Evaluate the Effect of SLV320 on Renal Function in Patients With Worsening Heart Failure
Public ClinicalTrials.gov record NCT00744341. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-Blind, Placebo-Controlled, Randomized, Multi-Center, Dose-Finding Study of SLV320, a Selective A1 Adenosine Receptor Antagonist, to Evaluate the Effect on Renal Function and Safety in Subjects Hospitalized With Acute Decompensated Heart Failure and Renal Dysfunction (Reno-Defend 1)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the efficacy and safety of IV SLV320 in acute heart failure patients with renal dysfunction.
Study identification
- NCT ID
- NCT00744341
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 46 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 2009 (Type not available)
- Primary completion
- Jan 2010 (Actual)
- Completion
- Jan 2010 (Actual)
- Last update posted
- Sep 17, 2010
2009 – 2010
United States locations
- U.S. sites
- 28
- U.S. states
- 18
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| S320.2.011 Site # 548 | Alameda | California | — | — |
| S320.2.011 Site # 566 | Banning | California | — | — |
| S320.2.011 Site # 551 | Inglewood | California | — | — |
| S320.2.011 Site # 564 | Bridgeport | Connecticut | — | — |
| S320.2.011 Site # 505 | Hollywood | Florida | — | — |
| S320.2.011 Site # 507 | Jacksonville | Florida | — | — |
| S320.2.011 Site # 532 | Riverdale | Georgia | — | — |
| S320.2.011 Site # 513 | Chicago | Illinois | — | — |
| S320.2.011 Site # 561 | Indianapolis | Indiana | — | — |
| S320.2.011 Site # 526 | Owensboro | Kentucky | — | — |
| S320.2.011 Site # 504 | Natchitoches | Louisiana | — | — |
| S320.2.011 Site # 546 | Biddeford | Maine | — | — |
| S320.2.011 Site # 523 | Dearborn | Michigan | — | — |
| S320.2.011 Site # 534 | Detroit | Michigan | — | — |
| S320.2.011 Site # 558 | Detroit | Michigan | — | — |
| S320.2.011 Site # 508 | St Louis | Missouri | — | — |
| S320.2.011 Site # 541 | Brooklyn | New York | — | — |
| S320.2.011 Site # 537 | New York | New York | — | — |
| S320.2.011 Site # 521 | Akron | Ohio | — | — |
| S320.2.011 Site # 527 | Toledo | Ohio | — | — |
| S320.2.011 Site # 528 | Philadelphia | Pennsylvania | — | — |
| S320.2.011 Site # 510 | Colombia | South Carolina | — | — |
| S320.2.011 Site # 545 | Nashville | Tennessee | — | — |
| S320.2.011 Site # 519 | Tullahoma | Tennessee | — | — |
| S320.2.011 Site # 511 | Houston | Texas | — | — |
| S320.2.011 Site # 518 | San Antonio | Texas | — | — |
| S320.2.011 Site # 556 | Manitowoc | Wisconsin | — | — |
| S320.2.011 Site # 565 | Milwaukee | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 77 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00744341, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 17, 2010 · Synced Nov 1, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00744341 live on ClinicalTrials.gov.